Key developmental processes of cell fate decisions and morphogenetic transformations
take place during the periimplantation and early postimplantation stages of mouse
embryogenesis. However analysing these fundamental events relies on direct observations
of cultured embryos, which are challenging to obtain. To address this challenge, here
we provide a detailed protocol describing a workflow for isolating early implanted
embryos, removing of redundant extraembryonic tissues and describing the culture conditions
that support further embryo development in vitro.
