Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

Schwartz, Gregory G; Steg, P Gabriel; Szarek, Michael; Bhatt, Deepak L; Bittner, Vera A; Diaz, Rafael; Edelberg, Jay M; Goodman, Shaun G; Hanotin, Corinne; Harrington, Robert A; Jukema, J Wouter; Lecorps, Guillaume; Mahaffey, Kenneth W; Moryusef, Angèle; Pordy, Robert; Quintero, Kirby; Roe, Matthew T; Sasiela, William J; Tamby, Jean-François; Tricoci, Pierluigi; White, Harvey D; Zeiher, Andreas M; Diaz, Rafael [Collaborator]; ODYSSEY OUTCOMES Committees and Investigators [Collaborative Organization]; Aylward, Philip E [Collaborator]; Drexel, Heinz [Collaborator]; Sinnaeve, Peter [Collaborator]; Dilic, Mirza [Collaborator]; Lopes, Renato D [Collaborator]; Gotcheva, Nina N [Collaborator]; Goodman, Shaun G [Collaborator]; Prieto, Juan-Carlos [Collaborator]; Yong, Huo [Collaborator]; López-Jaramillo, Patricio [Collaborator]; Pećin, Ivan [Collaborator]; Reiner, Zeljko [Collaborator]; Ostadal, Petr [Collaborator]; Poulsen, Steen Hvitfeldt [Collaborator]; Viigimaa, Margus [Collaborator]; Nieminen, Markku S [Collaborator]; Danchin, Nicolas [Collaborator]; Chumburidze, Vakhtang [Collaborator]; Marx, Nikolaus [Collaborator]; Liberopoulos, Evangelos [Collaborator]; Montenegro Valdovinos, Pablo Carlos [Collaborator]; Tse, Hung-Fat [Collaborator]; Kiss, Robert Gabor [Collaborator]; Xavier, Denis [Collaborator]; Zahger, Doron [Collaborator]; Valgimigli, Marco [Collaborator]; Kimura, Takeshi [Collaborator]; Kim, Hyo Soo [Collaborator]; Kim, Sang-Hyun [Collaborator]; Erglis, Andrejs [Collaborator]; Laucevicius, Aleksandras [Collaborator]; Kedev, Sasko [Collaborator]; Yusoff, Khalid [Collaborator]; Ramos López, Gabriel Arturo [Collaborator]; Alings, Marco [Collaborator]; White, Harvey D [Collaborator]; Halvorsen, Sigrun [Collaborator]; Correa Flores, Roger M [Collaborator]; Sy, Rody G [Collaborator]; Budaj, Andrzej [Collaborator]; Morais, Joao [Collaborator]; Dorobantu, Maria [Collaborator]; Karpov, Yuri [Collaborator]; Ristic, Arsen D [Collaborator]; Chua, Terrance [Collaborator]; Murin, Jan [Collaborator]; Fras, Zlatko [Collaborator]; Dalby, Anthony J [Collaborator]; Tuñón, José [Collaborator]; de Silva, H Asita [Collaborator]; Hagström, Emil [Collaborator]; Müller, Christian [Collaborator]; Chiang, Chern-En [Collaborator]; Sritara, Piyamitr [Collaborator]; Guneri, Sema [Collaborator]; Parkhomenko, Alexander [Collaborator]; Ray, Kausik K [Collaborator]; Moriarty, Patrick M [Collaborator]; Roe, Matthew T [Collaborator]; Vogel, Robert [Collaborator]; Schiavi, Lilia B [Collaborator]; Garrido, Marcelo [Collaborator]; Alvarisqueta, Andrés F [Collaborator]; Sassone, Sonia A [Collaborator]; Bordonava, Anselmo P [Collaborator]; Alves De Lima, Alberto E [Collaborator]; Schmidberg, Jorge M [Collaborator]; Duronto, Ernesto A [Collaborator]; Caruso, Orlando C [Collaborator]; Novaretto, Leonardo P [Collaborator]; Hominal, Miguel Angel [Collaborator]; Montaña, Oscar R [Collaborator]; Caccavo, Alberto [Collaborator]; Gomez Vilamajo, Oscar A [Collaborator]; Lorenzatti, Alberto J [Collaborator]; Cartasegna, Luis R [Collaborator]; Paterlini, Gustavo A [Collaborator]; Mackinnon, Ignacio J [Collaborator]; Caime, Guillermo D [Collaborator]; Amuchastegui, Marcos [Collaborator]; Codutti, Oscar R [Collaborator]; Jure, Horacio O [Collaborator]; Bono, Julio O E [Collaborator]; Hrabar, Adrian D [Collaborator]; Vallejos, Julio A [Collaborator]; Ahuad Guerrero, Rodolfo A [Collaborator]; Novoa, Federico [Collaborator]; Patocchi, Cristian A [Collaborator]; Zaidman, Cesar J [Collaborator]; Giuliano, Maria E [Collaborator]; Dran, Ricardo D [Collaborator]; Vico, Marisa L [Collaborator]; Carnero, Gabriela S [Collaborator]; Guzman, Pablo N [Collaborator]; Medrano Allende, Juan C [Collaborator]; Garcia Brasca, Daniela F [Collaborator]; Bustamante Labarta, Miguel H [Collaborator]; Nani, Sebastian [Collaborator]; Blumberg, Eduardo D S [Collaborator]; Colombo, Hugo R [Collaborator]; Liberman, Alberto [Collaborator]; Luciardi, Hector L [Collaborator]; Waisman, Gabriel D [Collaborator]; Berli, Mario A [Collaborator]; Garcia Duran, Ruben O [Collaborator]; Cestari, Horacio G [Collaborator]; Luquez, Hugo A [Collaborator]; Giordano, Jorge A [Collaborator]; Saavedra, Silvia S [Collaborator]; Waites, Jonathon H [Collaborator]; Collins, Nicholas [Collaborator]; Soward, Allan [Collaborator]; Hii, Chris L S [Collaborator]; Shaw, James [Collaborator]; Arstall, Margaret A [Collaborator]; Horowitz, John [Collaborator]; Rogers, James F [Collaborator]; Colquhoun, David [Collaborator]; Oqueli Flores, Romulo E [Collaborator]; Roberts-Thomson, Philip [Collaborator]; Raffel, Owen [Collaborator]; Lehman, Sam J [Collaborator]; Coverdale, Steven G M [Collaborator]; Garrahy, Paul J [Collaborator]; Starmer, Gregory [Collaborator]; Sader, Mark [Collaborator]; Carroll, Patrick A [Collaborator]; Zweiker, Robert [Collaborator]; Hoppe, Uta [Collaborator]; Huber, Kurt [Collaborator]; Berger, Rudolf [Collaborator]; Weidinger, Franz [Collaborator]; Faes, Dirk [Collaborator]; Hermans, Kurt [Collaborator]; Pirenne, Bruno [Collaborator]; Leone, Attilio [Collaborator]; Hoffer, Etienne [Collaborator]; Vrolix, Mathias C M [Collaborator]; De Wolf, Luc [Collaborator]; Wollaert, Bart [Collaborator]; Castadot, Marc [Collaborator]; Dujardin, Karl [Collaborator]; Beauloye, Christophe [Collaborator]; Vervoort, Geert [Collaborator]; Striekwold, Harry [Collaborator]; Convens, Carl [Collaborator]; Roosen, John [Collaborator]; Barbato, Emanuele [Collaborator]; Claeys, Marc [Collaborator]; Cools, Frank [Collaborator]; Terzic, Ibrahim [Collaborator]; Barakovic, Fahir [Collaborator]; Midzic, Zlatko [Collaborator]; Pojskic, Belma [Collaborator]; Fazlibegovic, Emir [Collaborator]; Durak-Nalbantic, Azra [Collaborator]; Vulic, Dusko [Collaborator]; Muslibegovic, Adis [Collaborator]; Reis, Gilmar [Collaborator]; Sousa, Luciano [Collaborator]; Nicolau, Jose C [Collaborator]; Giorgeto, Flavio E [Collaborator]; Silva, Ricardo P [Collaborator]; Nigro Maia, Lilia [Collaborator]; Rech, Rafael [Collaborator]; Rossi, Paulo R F [Collaborator]; Cerqueira, Maria José A G [Collaborator]; Duda, Norberto [Collaborator]; Kalil, Renato [Collaborator]; Kormann, Adrian [Collaborator]; Abrantes, José Antonio M [Collaborator]; Pimentel Filho, Pedro [Collaborator]; Soggia, Ana Priscila [Collaborator]; de Santos, Mayler O N [Collaborator]; Neuenschwander, Fernando [Collaborator]; Bodanese, Luiz C [Collaborator]; Michalaros, Yorghos L [Collaborator]; Eliaschewitz, Freddy G [Collaborator]; Vidotti, Maria H [Collaborator]; Leaes, Paulo E [Collaborator]; Botelho, Roberto V [Collaborator]; Kaiser, Sergio [Collaborator]; Fernandes Manenti, Euler Roberto F [Collaborator]; Precoma, Dalton B [Collaborator]; Moura Jorge, Jose C [Collaborator]; de B Silva, Pedro G M [Collaborator]; Silveira, Jose A [Collaborator]; Saporito, Wladmir [Collaborator]; Marin Neto, Jose A [Collaborator]; Feitosa, Gilson S [Collaborator]; F Ritt, Luiz Eduardo [Collaborator]; de Souza, Juliana A [Collaborator]; Costa, Fernando [Collaborator]; Souza, Weimar K S B [Collaborator]; Reis, Helder J L [Collaborator]; Saporito, Wladimir [Collaborator]; Machado, Leandro [Collaborator]; Aidar Ayoub, José Carlos [Collaborator]; Todorov, Georgi V [Collaborator]; Nikolov, Fedya P [Collaborator]; Velcheva, Elena S [Collaborator]; Tzekova, Maria L [Collaborator]; Benov, Haralambi O [Collaborator]; Petranov, Stanislav L [Collaborator]; Tumbev, Haralin S [Collaborator]; Shehova-Yankova, Nina S [Collaborator]; Markov, Dimitar T [Collaborator]; Raev, Dimitar H [Collaborator]; Mollov, Mihail N [Collaborator]; Kichukov, Kostadin N [Collaborator]; Ilieva-Pandeva, Katya A [Collaborator]; Ivanova, Raya [Collaborator]; Mincheva, Valentina M [Collaborator]; Lazov, Petar V [Collaborator]; Dimov, Bojidar I [Collaborator]; Senaratne, Manohara [Collaborator]; Stone, James [Collaborator]; Kornder, Jan [Collaborator]; Pearce, Stephen [Collaborator]; Dion, Danielle [Collaborator]; Savard, Daniel [Collaborator]; Pesant, Yves [Collaborator]; Pandey, Amritanshu [Collaborator]; Robinson, Simon [Collaborator]; Gosselin, Gilbert [Collaborator]; Vizel, Saul [Collaborator]; Hoag, Gordon [Collaborator]; Bourgeois, Ronald [Collaborator]; Morisset, Anne [Collaborator]; Sabbah, Eric [Collaborator]; Sussex, Bruce [Collaborator]; Kouz, Simon [Collaborator]; MacDonald, Paul [Collaborator]; Diaz, Ariel [Collaborator]; Michaud, Nicolas [Collaborator]; Fell, David [Collaborator]; Leung, Raymond [Collaborator]; Vuurmans, Tycho [Collaborator]; Lai, Christopher [Collaborator]; Nigro, Frank [Collaborator]; Davies, Richard [Collaborator]; Nogareda, Gustavo [Collaborator]; Vijayaraghavan, Ram [Collaborator]; Ducas, John [Collaborator]; Lepage, Serge [Collaborator]; Mehta, Shamir [Collaborator]; Cha, James [Collaborator]; Dupuis, Robert [Collaborator]; Fong, Peter [Collaborator]; Rodes-Cabau, Josep [Collaborator]; Fadlallah, Hussein [Collaborator]; Cleveland, David [Collaborator]; Huynh, Thao [Collaborator]; Bata, Iqbal [Collaborator]; Hameed, Adnan [Collaborator]; Pincetti, Cristian [Collaborator]; Potthoff, Sergio [Collaborator]; Prieto, Juan C [Collaborator]; Acevedo, Monica [Collaborator]; Aguirre, Arnoldo [Collaborator]; Vejar, Margarita [Collaborator]; Yañez, Mario [Collaborator]; Araneda, Guillermo [Collaborator]; Fernandez, Mauricio [Collaborator]; Perez, Luis [Collaborator]; Varleta, Paola [Collaborator]; Florenzano, Fernando [Collaborator]; Huidobro, Laura [Collaborator]; Raffo, Carlos A [Collaborator]; Olivares, Claudia [Collaborator]; Chen, Jiyan [Collaborator]; Dong, Yugang [Collaborator]; Huang, Weijian [Collaborator]; Wang, Jianzhong [Collaborator]; Huang, Shi'An [Collaborator]; Yao, Zhuhua [Collaborator]; Cui, Lan [Collaborator]; Lin, Wenhua [Collaborator]; Sun, Yuemin [Collaborator]; Wang, Jingfeng [Collaborator]; Li, Jianping [Collaborator]; Zhang, Xuelian [Collaborator]; Zhu, Hong [Collaborator]; Chen, Dandan [Collaborator]; Huang, Lan [Collaborator]; Dong, Shaohong [Collaborator]; Su, Guohai [Collaborator]; Xu, Biao [Collaborator]; Su, Xi [Collaborator]; Cheng, Xiaoshu [Collaborator]; Lin, Jinxiu [Collaborator]; Zong, Wenxia [Collaborator]; Li, Huanming [Collaborator]; Feng, Yi [Collaborator]; Xu, Dingli [Collaborator]; Yang, Xinchun [Collaborator]; Ke, Yuannan [Collaborator]; Lin, Xuefeng [Collaborator]; Zhang, Zheng [Collaborator]; Zheng, Zeqi [Collaborator]; Luo, Zhurong [Collaborator]; Chen, Yundai [Collaborator]; Ding, Chunhua [Collaborator]; Zheng, Yang [Collaborator]; Li, Xiaodong [Collaborator]; Peng, Daoquan [Collaborator]; Li, Ying [Collaborator]; Wei, Meng [Collaborator]; Liu, Shaowen [Collaborator]; Yu, Yihua [Collaborator]; Qu, Baiming [Collaborator]; Jiang, Weihong [Collaborator]; Zhou, Yujie [Collaborator]; Zhao, Xingsheng [Collaborator]; Yuan, Zuyi [Collaborator]; Guo, Ying [Collaborator]; Xu, Xiping [Collaborator]; Shi, Xubo [Collaborator]; Ge, Junbo [Collaborator]; Fu, Guosheng [Collaborator]; Bai, Feng [Collaborator]; Fang, Weiyi [Collaborator]; Shou, Xiling [Collaborator]; Yang, Xiangjun [Collaborator]; Wang, Jian'An [Collaborator]; Jaramillo, Nicolas [Collaborator]; Sanchez Vallejo, Gregorio [Collaborator]; Luna Botia, Diana C [Collaborator]; Botero Lopez, Rodrigo [Collaborator]; Molina De Salazar, Dora I [Collaborator]; Cadena Bonfanti, Alberto J [Collaborator]; Diego Higuera, Juan [Collaborator]; Barrera Silva, Sandra I [Collaborator]; Garcia Lozada, Henry J [Collaborator]; Coronel Arroyo, Julian A [Collaborator]; Accini Mendoza, Jose L [Collaborator]; Fernandez Ruiz, Ricardo L [Collaborator]; Fernandez, Angela M [Collaborator]; Manzur Jatin, Fernando G [Collaborator]; Sotomayor Herazo, Aristides [Collaborator]; Castellanos Parada, Jeffrey [Collaborator]; Urina Triana, Miguel A [Collaborator]; Strozzi, Maja [Collaborator]; Car, Siniša [Collaborator]; Miličić, Davor [Collaborator]; Benčić, Martina Lovrić [Collaborator]; Pintarić, Hrvoje [Collaborator]; Prvulović, Đeiti [Collaborator]; Šikić, Jozica [Collaborator]; Peršić, Viktor [Collaborator]; Mileta, Dean [Collaborator]; Štambuk, Kresimir [Collaborator]; Babić, Zdravko [Collaborator]; Spinar, Jindrich [Collaborator]; Horak, David [Collaborator]; Stasek, Josef [Collaborator]; Alan, David [Collaborator]; Machova, Vilma [Collaborator]; Linhart, Ales [Collaborator]; Novotny, Vojtech [Collaborator]; Kaucak, Vladimir [Collaborator]; Rokyta, Richard [Collaborator]; Naplava, Robert [Collaborator]; Coufal, Zdenek [Collaborator]; Adamkova, Vera [Collaborator]; Podpera, Ivo [Collaborator]; Zizka, Jiri [Collaborator]; Motovska, Zuzana [Collaborator]; Marusincova, Ivana [Collaborator]; Svab, Premysl [Collaborator]; Heinc, Petr [Collaborator]; Kuchar, Jiri [Collaborator]; Povolny, Petr [Collaborator]; Poulsen, Steen H [Collaborator]; Raungaard, Bent [Collaborator]; Clemmensen, Peter [Collaborator]; Bang, Lia E [Collaborator]; May, Ole [Collaborator]; Bøttcher, Morten [Collaborator]; Hove, Jens D [Collaborator]; Frost, Lars [Collaborator]; Gislason, Gunnar [Collaborator]; Larsen, John [Collaborator]; Johansen, Peter Betton [Collaborator]; Hald, Flemming [Collaborator]; Jeppesen, Jørgen [Collaborator]; Nielsen, Tonny [Collaborator]; Kristensen, Kjeld S [Collaborator]; Walichiewicz, Piotr Maria [Collaborator]; Lomholdt, Jens D [Collaborator]; Klausen, Ib C [Collaborator]; Nielsen, Peter Kaiser [Collaborator]; Davidsen, Flemming [Collaborator]; Videbaek, Lars [Collaborator]; Soots, Mai [Collaborator]; Vahula, Veiko [Collaborator]; Hedman, Anu [Collaborator]; Soopõld, Üllar [Collaborator]; Märtsin, Kaja [Collaborator]; Taskinen, Marja-Riitta [Collaborator]; Porthan, Kimmo [Collaborator]; Airaksinen, Juhani K [Collaborator]; Juonala, Markus [Collaborator]; Kiviniemi, Tuomas [Collaborator]; Vikman, Saila [Collaborator]; Posio, Pirjo [Collaborator]; Taurio, Jyrki [Collaborator]; Huikuri, Heikki [Collaborator]; Kaikkonen, Kari [Collaborator]; Coste, Pierre [Collaborator]; Ferrari, Emile [Collaborator]; Morel, Olivier [Collaborator]; Montalescot, Gilles [Collaborator]; Barone-Rochette, Gilles [Collaborator]; Mansourati, Jacques [Collaborator]; Cottin, Yves [Collaborator]; Steg, Philippe Gabriel [Collaborator]; Leclercq, Florence [Collaborator]; Belhassane, Abdelkader [Collaborator]; Delarche, Nicolas [Collaborator]; Boccara, Franck [Collaborator]; Paganelli, Franck [Collaborator]; Clerc, Jérôme [Collaborator]; Schiele, Francois [Collaborator]; Aboyans, Victor [Collaborator]; Probst, Vincent [Collaborator]; Berland, Jacques [Collaborator]; Lefèvre, Thierry [Collaborator]; Khintibidze, Irakli [Collaborator]; Shaburishvili, Tamaz [Collaborator]; Pagava, Zurab [Collaborator]; Ghlonti, Ramaz [Collaborator]; Lominadze, Zaza [Collaborator]; Khabeishvili, George [Collaborator]; Hemetsberger, Rayyan [Collaborator]; Rauch-Kröhnert, Ursula [Collaborator]; Stratmann, Matthias [Collaborator]; Appel, Karl-Friedrich [Collaborator]; Schmidt, Ekkehard [Collaborator]; Omran, Heyder [Collaborator]; Stellbrink, Christoph [Collaborator]; Dorsel, Thomas [Collaborator]; Lianopoulos, Emmanouil [Collaborator]; Marx, Roger [Collaborator]; Zirlik, Andreas [Collaborator]; Schellenberg, Detlev [Collaborator]; Heitzer, Thomas [Collaborator]; Laufs, Ulrich [Collaborator]; Gielen, Stephan [Collaborator]; Winkelmann, Bernhard [Collaborator]; Behrens, Steffen [Collaborator]; Sydow, Karsten [Collaborator]; Simonis, Gregor [Collaborator]; Muenzel, Thomas [Collaborator]; Werner, Nikos [Collaborator]; Leggewie, Stefan [Collaborator]; Böcker, Dirk [Collaborator]; Braun-Dullaeus, Rüdiger [Collaborator]; Toursarkissian, Nicole [Collaborator]; Jeserich, Michael [Collaborator]; Weißbrodt, Matthias [Collaborator]; Schaeufele, Tim [Collaborator]; Weil, Joachim [Collaborator]; Völler, Heinz [Collaborator]; Waltenberger, Johannes [Collaborator]; Natour, Mohammed [Collaborator]; Steiner, Stephan [Collaborator]; Heidenreich, Lothar [Collaborator]; Gremmler, Uwe [Collaborator]; Killat, Holger [Collaborator]; Patsilinakos, Sotiris [Collaborator]; Kartalis, Athanasios [Collaborator]; Manolis, Athanassios [Collaborator]; Sionis, Dimitrios [Collaborator]; Skoumas, Ioannis [Collaborator]; Athyros, Vasilios [Collaborator]; Vardas, Panagiotis [Collaborator]; Parthenakis, Frangkiskos [Collaborator]; Alexopoulos, Dimitrios [Collaborator]; Hahalis, Georgios [Collaborator]; Lekakis, John [Collaborator]; Xatzitolios, Apostolos [Collaborator]; Fausto Ovando, Sergio R [Collaborator]; Arango Benecke, Juan L [Collaborator]; Rodriguez De Leon, Edgar R [Collaborator]; Yan, Bryan P Y [Collaborator]; Siu, David C W [Collaborator]; Turi, Tibor [Collaborator]; Merkely, Bela [Merkely, Béla Péter (Kardiológia), Collaborator] Cardiovascular Center (SU / FM / C); Ungi, Imre [Ungi, Imre (Kardiológia), Collaborator] Second Department of Internal Medicine and Card... (SZTE / ASZMS / DIMedicine); Lupkovics, Geza [Collaborator]; Nagy, Lajos [Collaborator]; Katona, András [Collaborator]; Édes, István [Collaborator]; Müller, Gábor [Collaborator]; Horvath, Iván [Horváth, Iván (Kardiológia), Collaborator]; Kapin, Tibor [Collaborator]; Faluközy, József [Collaborator]; Kumbla, Mukund [Collaborator]; Sandhu, Manjinder [Collaborator]; Annam, Sharath [Collaborator]; Proddutur, Naveen Reddy [Collaborator]; Premchand, Rajendra K [Collaborator]; Mahajan, Ajaykumar [Collaborator]; Abhyanakar, Atul D [Collaborator]; Kerkar, Prafulla [Collaborator]; Govinda, Ravishankar A [Collaborator]; Oomman, Abraham [Collaborator]; Sinha, Dhurjati [Collaborator]; Patil, Sachin N [Collaborator]; Kahali, Dhiman [Collaborator]; Sawhney, Jitendra [Collaborator]; Joshi, Abhijeet B [Collaborator]; Chaudhary, Sanjeev [Collaborator]; Harkut, Pankaj [Collaborator]; Guha, Santanu [Collaborator]; Porwal, Sanjay [Collaborator]; Jujjuru, Srimannarayana [Collaborator]; Pothineni, Ramesh B [Collaborator]; Monteiro, Minguel R [Collaborator]; Khan, Aziz [Collaborator]; Iyengar, Shamanna S [Collaborator]; Grewal, Jasprakash Singh [Collaborator]; Chopda, Manoj [Collaborator]; Fulwani, Mahesh C [Collaborator]; Patange, Aparna [Collaborator]; Chopra, Vijay K [Collaborator]; Goyal, Naresh K [Collaborator]; Shinde, Rituparna [Collaborator]; Manakshe, Gajendra V [Collaborator]; Patki, Nitin [Collaborator]; Sethi, Sumeet [Collaborator]; Munusamy, Vengatesh [Collaborator]; Karna, Sunil [Collaborator]; Adhyapak, Srilakshmi [Collaborator]; Pandurangi, Ulhas [Collaborator]; Mathur, Rishabh [Collaborator]; Kalashetti, Suhas [Collaborator]; Bhagwat, Ajit [Collaborator]; Raghuraman, Bagirath [Collaborator]; Yerra, Shiv Kumar [Collaborator]; Bhansali, Prasant [Collaborator]; Borse, Rohidas [Collaborator]; Das, Srihari [Collaborator]; Abdullakutty, Jabir [Collaborator]; Saathe, Shireesh [Collaborator]; Palimkar, Priya [Collaborator]; Atar, Shaul [Collaborator]; Shechter, Michael [Collaborator]; Mosseri, Morris [Collaborator]; Arbel, Yaron [Collaborator]; Lotan, Chaim [Collaborator]; Rosenschein, Uri [Collaborator]; Katz, Amos [Collaborator]; Henkin, Yaakov [Collaborator]; Francis, Adi [Collaborator]; Klutstein, Marc [Collaborator]; Nikolsky, Eugenia [Collaborator]; Turgeman, Yoav [Collaborator]; Halabi, Majdi [Collaborator]; Kornowski, Ran [Collaborator]; Jonas, Michael [Collaborator]; Amir, Offer [Collaborator]; Rozenman, Yoseph [Collaborator]; Fuchs, Shmuel [Collaborator]; Hussein, Osamah [Collaborator]; Gavish, Dov [Collaborator]; Vered, Zvi [Collaborator]; Caraco, Yoseph [Collaborator]; Elias, Mazen [Collaborator]; Tov, Naveh [Collaborator]; Piovaccari, Giancarlo [Collaborator]; De Pellegrin, Annamaria [Collaborator]; Guardigli, Gabriele [Collaborator]; Licciardello, Giovanni [Collaborator]; Auguadro, Carla [Collaborator]; Cuccia, Claudio [Collaborator]; Salvioni, Alessandro [Collaborator]; Musumeci, Giuseppe [Collaborator]; Calabrò, Paolo [Collaborator]; Novo, Salvatore [Collaborator]; Faggiano, Pompilio [Collaborator]; De Cesare, Nicoletta B [Collaborator]; Berti, Sergio [Collaborator]; Cavallini, Claudio [Collaborator]; Puccioni, Enrico [Collaborator]; Galvani, Marcello [Collaborator]; Tespili, Maurizio [Collaborator]; Piatti, Piermarco [Collaborator]; Palvarini, Michela [Collaborator]; De Luca, Giuseppe [Collaborator]; Violini, Roberto [Collaborator]; De Leo, Alessandro [Collaborator]; Perrone Filardi, Pasquale [Collaborator]; Ferratini, Maurizio [Collaborator]; Dai, Kazuoki [Collaborator]; Kamiya, Haruo [Collaborator]; Ando, Kenji [Collaborator]; Takeda, Yoshihiro [Collaborator]; Morino, Yoshihiro [Collaborator]; Hata, Yoshiki [Collaborator]; Kimura, Kazuo [Collaborator]; Kishi, Koichi [Collaborator]; Michishita, Ichiro [Collaborator]; Uehara, Hiroki [Collaborator]; Higashikata, Toshinori [Collaborator]; Hirayama, Atsushi [Collaborator]; Hirooka, Keiji [Collaborator]; Sakagami, Satoru [Collaborator]; Taguchi, Shuichi [Collaborator]; Koike, Akihiro [Collaborator]; Fujinaga, Hiroyuki [Collaborator]; Koba, Shinji [Collaborator]; Kozuma, Ken [Collaborator]; Kawasaki, Tomohiro [Collaborator]; Ono, Yujiro [Collaborator]; Shimizu, Masatoshi [Collaborator]; Katsuda, Yousuke [Collaborator]; Wada, Atsuyuki [Collaborator]; Shinke, Toshiro [Collaborator]; Ako, Junya [Collaborator]; Fujii, Kenshi [Collaborator]; Takahashi, Toshiyuki [Collaborator]; Sakamoto, Tomohiro [Collaborator]; Furukawa, Yutaka [Collaborator]; Sugino, Hiroshi [Collaborator]; Mano, Toshiaki [Collaborator]; Utsu, Noriaki [Collaborator]; Ito, Kashima [Collaborator]; Haraguchi, Takuya [Collaborator]; Ueda, Yasunori [Collaborator]; Nishibe, Akira [Collaborator]; Fujimoto, Kazuteru [Collaborator]; Yoon, Jung Han [Collaborator]; Park, Hun Sik [Collaborator]; Chae, In-Ho [Collaborator]; Kim, Moo Hyun [Collaborator]; Jeong, Myung Ho [Collaborator]; Rha, Seungwoon [Collaborator]; Kim, Chongjin [Collaborator]; Kim, Hyo-Soo [Collaborator]; Hong, Taekjong [Collaborator]; Busmane, Arija [Collaborator]; Pontaga, Natalija [Collaborator]; Strelnieks, Aldis [Collaborator]; Mintale, Iveta [Collaborator]; Sime, Iveta [Collaborator]; Petrulioniene, Zaneta [Collaborator]; Kavaliauskiene, Roma [Collaborator]; Jurgaitiene, Ruta [Collaborator]; Sakalyte, Gintare [Collaborator]; Slapikas, Rimvydas [Collaborator]; Norkiene, Sigute [Collaborator]; Misonis, Nerijus [Collaborator]; Kibarskis, Aleksandras [Collaborator]; Kubilius, Raimondas [Collaborator]; Bojovski, Stojko [Collaborator]; Lozance, Nensi [Collaborator]; Kjovkaroski, Aleksandar [Collaborator]; Doncovska, Snezana [Collaborator]; Ong, Tiong Kiam [Collaborator]; Kasim, Sazzli [Collaborator]; Maskon, Oteh [Collaborator]; Kandasamy, Balachandran [Collaborator]; Liew, Houng B [Collaborator]; Wan Mohamed, Wan Mohd Izani [Collaborator]; García Castillo, Armando [Collaborator]; Carrillo Calvillo, Jorge [Collaborator]; Fajardo Campos, Pedro [Collaborator]; Núñez Fragoso, Juan Carlos [Collaborator]; Bayram Llamas, Edmundo Alfredo [Collaborator]; Alcocer Gamba, Marco Antonio [Collaborator]; Carranza Madrigal, Jaime [Collaborator]; González Salas, Luis Gerardo [Collaborator]; López Rosas, Enrique [Collaborator]; González Díaz, Belinda [Collaborator]; Salcido Vázquez, Eduardo [Collaborator]; Nacoud Ackar, Alfredo [Collaborator]; Llamas Esperón, Guillermo Antonio [Collaborator]; Martínez Sánchez, Carlos Rodolfo [Collaborator]; Guerrero De Leon, María [Collaborator]; Suarez Otero, Rodrigo [Collaborator]; Fanghänel Salmón, Guillermo [Collaborator]; Pérez Ríos, Jesús Antonio [Collaborator]; Garza Ruíz, José Angel [Collaborator]; Breedveld, Robert W [Collaborator]; Hoogslag, Pieter A M [Collaborator]; Suryapranata, Harry [Collaborator]; Oomen, Antonius [Collaborator]; Wiersma, Jacobijne J [Collaborator]; Van Der Wal, Ruud M A [Collaborator]; Hooft Van Huysduynen-Monraats, Pascalle S [Collaborator]; Karalis, Ioannis [Collaborator]; Verdel, Gerardus J E [Collaborator]; Brueren, Bart R G [Collaborator]; Troquay, Roland P Th [Collaborator]; Viergever, Eric P [Collaborator]; Al-Windy, Nadea Y Y [Collaborator]; Bartels, Gerard L [Collaborator]; Cornel, Jan H [Collaborator]; Hermans, Walter R M [Collaborator]; Herrman, Johannes P R [Collaborator]; Bos, Robert J [Collaborator]; Groutars, Reginald G E J [Collaborator]; Van Der Zwaan, Coenraad C [Collaborator]; Kaplan, Refik [Collaborator]; Ronner, Eelko [Collaborator]; Groenemeijer, Bjorn E [Collaborator]; Bronzwaer, Patrick N A [Collaborator]; Liem, Anho A H [Collaborator]; Rensing, Bernard J W M [Collaborator]; Bokern, Marcel J J A [Collaborator]; Nijmeijer, Remco [Collaborator]; Hersbach, Ferry M R J [Collaborator]; Willems, Frank F [Collaborator]; Gosselink, Antonius T M [Collaborator]; Elliott, John [Collaborator]; Wilkins, Gerard [Collaborator]; Fisher, Raewyn [Collaborator]; Scott, Douglas [Collaborator]; Hart, Hamish [Collaborator]; Stewart, Ralph [Collaborator]; Harding, Scott [Collaborator]; Ternouth, Ian [Collaborator]; Fisher, Nicholas [Collaborator]; Aitken, Denise [Collaborator]; Anscombe, Russell [Collaborator]; Tomala, Tadeusz [Collaborator]; Nygård, Ottar [Collaborator]; Sparby, Jon Arne [Collaborator]; Andersen, Kjell [Collaborator]; Gullestad, Lars [Collaborator]; Jortveit, Jarle [Collaborator]; Munk, Peter S [Collaborator]; Hurtig, Ulf [Collaborator]; Calderon Ticona, Jorge R [Collaborator]; Durand Velasquez, Julio R [Collaborator]; Negron Miguel, Sandra A [Collaborator]; Sanabria Perez, Enrique S [Collaborator]; Carrion Chambilla, Jesus M [Collaborator]; Chavez Ayala, Carlos A [Collaborator]; Castillo Leon, Reynaldo P [Collaborator]; Vargas Gonzales, Rolando J [Collaborator]; Hernandez Zuniga, Jose D [Collaborator]; Camacho Cosavalente, Luis A [Collaborator]; Bravo Mannucci, Jorge E [Collaborator]; Llerena Navarro, Nassip C [Collaborator]; Roldan Concha, Yudy M [Collaborator]; Rodriguez Chavez, Víctor E [Collaborator]; Anchante Hernandez, Henry A [Collaborator]; Zea Nunez, Carlos A [Collaborator]; Ferrolino, Arthur [Collaborator]; Sy, Rosa Allyn G [Collaborator]; Tirador, Louie [Collaborator]; Matiga, Generoso [Collaborator]; Coching, Raul Martin [Collaborator]; Bernan, Alisa [Collaborator]; Rogelio, Gregorio [Collaborator]; Morales, Dante D [Collaborator]; Tan, Edgar [Collaborator]; Wlodarczak, Adrian [Collaborator]; Jaworska, Krystyna [Collaborator]; Skonieczny, Grzegorz [Collaborator]; Pawlowicz, Lidia [Collaborator]; Wojewoda, Pawel [Collaborator]; Busz-Papiez, Benita [Collaborator]; Bednarski, Janusz [Collaborator]; Goch, Aleksander [Collaborator]; Staneta, Pawel [Collaborator]; Dulak, Elzbieta [Collaborator]; Saminski, Krzysztof [Collaborator]; Krasowski, Wlodzimierz [Collaborator]; Sudnik, Wanda [Collaborator]; Zurakowski, Aleksander [Collaborator]; Skorski, Marcin [Collaborator]; Lysek, Roman [Collaborator]; Miklaszewicz, Beata [Collaborator]; Kubica, Jacek [Collaborator]; Lipko, Jan Andrzej [Collaborator]; Kostarska-Srokosz, Edyta [Collaborator]; Piepiorka, Marek [Collaborator]; Drzewiecka, Anna [Collaborator]; Sciborski, Ryszard [Collaborator]; Stasiewski, Arkadiusz [Collaborator]; Blicharski, Tomasz [Collaborator]; Bystryk, Leszek [Collaborator]; Szpajer, Michal [Collaborator]; Korol, Marek [Collaborator]; Czerski, Tomasz [Collaborator]; Mirek-Bryniarska, Ewa [Collaborator]; Gniot, Jacek [Collaborator]; Lubinski, Andrzej [Collaborator]; Gorny, Jerzy [Collaborator]; Franek, Edward [Collaborator]; Monteiro, Pedro [Collaborator]; Mesquita Bastos, Jose [Collaborator]; Pereira, Helder H [Collaborator]; Martins, Dinis [Collaborator]; Seixo, Filipe [Collaborator]; Mendonça, Carlos [Collaborator]; Botelho, Ana [Collaborator]; Minescu, Bogdan [Collaborator]; Istratoaie, Octavian [Collaborator]; Tesloianu, Dan N [Collaborator]; Cristian, Gabriel [Collaborator]; Podoleanu, Cristian G C [Collaborator]; Constantinescu, Mircea C A [Collaborator]; Bengus, Cristina M [Collaborator]; Militaru, Constantin [Collaborator]; Rosu, Doina [Collaborator]; Parepa, Irinel R [Collaborator]; Matei, Adrian V [Collaborator]; Alexandru, Tom M [Collaborator]; Shvarts, Yury [Collaborator]; Orlikova, Olga [Collaborator]; Kobalava, Zhanna [Collaborator]; Barbarash, Olga L [Collaborator]; Markov, Valentin [Collaborator]; Lyamina, Nadezhda [Collaborator]; Gordienko, Alexander [Collaborator]; Zrazhevsky, Konstantin [Collaborator]; Vishnevsky, Alexander Y [Collaborator]; Gurevich, Victor [Collaborator]; Stryuk, Raisa [Collaborator]; Lomakin, Nikita V [Collaborator]; Bokarev, Igor [Collaborator]; Shalaev, Sergey [Collaborator]; Khaisheva, Larisa [Collaborator]; Chizhov, Petr [Collaborator]; Viktorova, Inna [Collaborator]; Osokina, Natalya [Collaborator]; Akatova, Evgenia [Collaborator]; Chumakova, Galina [Collaborator]; Libov, Igor [Collaborator]; Voevoda, Mikhail I [Collaborator]; Tretyakova, Tatyana V [Collaborator]; Baranov, Evgeny [Collaborator]; Shustov, Sergey [Collaborator]; Yakushin, Sergey [Collaborator]; Gordeev, Ivan [Collaborator]; Khasanov, Niiaz [Collaborator]; Reshetko, Olga [Collaborator]; Sotnikova, Tatiana [Collaborator]; Molchanova, Olga [Collaborator]; Nikolaev, Konstantin [Collaborator]; Gapon, Liudmila [Collaborator]; Baranova, Elena [Collaborator]; Shogenov, Zaur [Collaborator]; Kosmachova, Elena [Collaborator]; Karpov, Yuriy [Collaborator]; Povzun, Anton [Collaborator]; Egorova, Liudmila [Collaborator]; Tyrenko, Vadim V [Collaborator]; Ivanov, Igor G [Collaborator]; Simic, Dragan [Collaborator]; Ivanovic, Nikola [Collaborator]; Davidovic, Goran [Collaborator]; Tasic, Nebojsa [Collaborator]; Asanin, Milika R [Collaborator]; Stojic, Stevo [Collaborator]; Apostolovic, Svetlana R [Collaborator]; Ilic, Stevan [Collaborator]; Putnikovic, Biljana [Collaborator]; Stankovic, Aleksandar [Collaborator]; Arandjelovic, Aleksandra [Collaborator]; Radovanovic, Slavica [Collaborator]; Balinovac, Jovan [Collaborator]; Dincic, Dragan V [Collaborator]; Seferovic, Petar [Collaborator]; Dodic, Slobodan [Collaborator]; Dimkovic, Sinisa [Collaborator]; Poh, Kian-Keong [Collaborator]; Ong, Hean Yee [Collaborator]; Micko, Karol [Collaborator]; Nociar, Jan [Collaborator]; Pella, Daniel [Collaborator]; Fulop, Peter [Collaborator]; Hranai, Marian [Collaborator]; Palka, Juraj [Collaborator]; Mazur, Juraj [Collaborator]; Majercák, Ivan [Collaborator]; Dzupina, Andrej [Collaborator]; Fazekas, František [Collaborator]; Gonsorcik, Jozef [Collaborator]; Bugan, Viliam [Collaborator]; Selecky, Juraj [Collaborator]; Kamensky, Gabriel [Collaborator]; Strbova, Jaroslava [Collaborator]; Smik, Rudolf [Collaborator]; Dukat, Andrej [Collaborator]; Žuran, Ivan [Collaborator]; Oklukar, Janez [Collaborator]; Šuligoj, Nataša Černič [Collaborator]; Cevc, Matija [Collaborator]; Lipar, Luka [Collaborator]; Cyster, Henry P [Collaborator]; Ranjith, Naresh [Collaborator]; Corbett, Clive [Collaborator]; Bayat, Junaid [Collaborator]; Makotoko, Ellen Makoali [Collaborator]; Kapp, Ilse E [Collaborator]; de V Basson, Matthys M [Collaborator]; Lottering, Hanlie [Collaborator]; Van Zyl, Louis J [Collaborator]; Sebastian, Peter J [Collaborator]; Pillay, Thayabran [Collaborator]; Saaiman, Jan A [Collaborator]; Commerford, Patrick J [Collaborator]; Cassimjee, Soraya [Collaborator]; Ebrahim, Iftikhar O [Collaborator]; Sarvan, Mahomed [Collaborator]; Mynhardt, Joseph H [Collaborator]; Reuter, Helmuth [Collaborator]; Moodley, Rajendran [Collaborator]; Vida, Manuel [Collaborator]; Cequier Fillat, Angel R [Collaborator]; Bodí Peris, Vicente [Collaborator]; Fuentes Jimenez, Francisco [Collaborator]; Marín, Francisco [Collaborator]; Cruz Fernández, Jose M [Collaborator]; Gil-Extremera, Blas [Collaborator]; Diz, Fernando Worner [Collaborator]; Garcia-Dorado, David [Collaborator]; Iñiguez, Andres [Collaborator]; Tuñón Fernández, José [Collaborator]; Gonzalez-Juanatey, Jose R [Collaborator]; Fernandez Portales, Javier [Collaborator]; Civeira Murillo, Fernando [Collaborator]; Matas Pericas, Laia [Collaborator]; Zamorano, Jose Luis [Collaborator]; De Mora Martin, Manuel [Collaborator]; Bruguera Cortada, Jordi [Collaborator]; Alonso Martin, Joaquin J [Collaborator]; De Berrazueta Fernández, José R [Collaborator]; Díaz Fernández, Jose Francisco [Collaborator]; García Lledó, José Alberto [Collaborator]; Cosín Sales, Juan [Collaborator]; Botas Rodriguez, Javier [Collaborator]; Gusi Tragant, Gabriel [Collaborator]; Benedicto, Amparo [Collaborator]; Gonzalez-Juanatey, Carlos [Collaborator]; Camprubí Potau, Mercedes [Collaborator]; Plaza Perez, Ignacio [Collaborator]; De La Tassa, César Morís [Collaborator]; Loma-Osorio Rincon, Pablo [Collaborator]; Balaguer Recena, Javier [Collaborator]; Escudier, Juan M [Collaborator]; Constantine, Godwin [Collaborator]; Haniffa, Ruvaiz [Collaborator]; Tissera, Nirmali [Collaborator]; Amarasekera, Stanley [Collaborator]; Fernando, Nimali [Collaborator]; Jayawardena, Jayanthimala [Collaborator]; Santharaj, Wijeyasingam [Collaborator]; Ekanayaka, Ruvan [Collaborator]; Mendis, Sepalika [Collaborator]; Senaratne, Vajira [Collaborator]; Mayurathan, Gnanamoorthy [Collaborator]; Sirisena, Thilak [Collaborator]; Rajapaksha, Ajantha [Collaborator]; Herath, Jagath I [Collaborator]; Amarasena, Naomali [Collaborator]; Berglund, Stefan [Collaborator]; Rasmanis, Gundars [Collaborator]; Witt, Nils [Collaborator]; Mourtzinis, Georgios [Collaborator]; Nicol, Peter [Collaborator]; Hansen, Ole [Collaborator]; Romeo, Stefano [Collaborator]; Jensen, Steen Agergaard [Collaborator]; Torstensson, Ingemar [Collaborator]; Ahremark, Ulf [Collaborator]; Sundelin, Torbjörn [Collaborator]; Moccetti, Tiziano [Collaborator]; Mach, Francois [Collaborator]; Binder, Ronald [Collaborator]; Tsai, Wei-Chuan [Collaborator]; Ueng, Kwo-Chang [Collaborator]; Lai, Wen-Ter [Collaborator]; Liu, Ming-En [Collaborator]; Hwang, Juey-Jen [Collaborator]; Yin, Wei-Hsian [Collaborator]; Hsieh, I-Chang [Collaborator]; Lin, Wei Hsiang [Collaborator]; Kuo, Jen-Yuan [Collaborator]; Huang, Tsuei-Yuan [Collaborator]; Fang, Chih-Yuan [Collaborator]; Kaewsuwanna, Pinij [Collaborator]; Soonfuang, Wasant [Collaborator]; Jintapakorn, Woravut [Collaborator]; Sukonthasarn, Apichard [Collaborator]; Wongpraparut, Nattawut [Collaborator]; Sastravaha, Krisada [Collaborator]; Sansanayudh, Nakarin [Collaborator]; Kehasukcharoen, Wirash [Collaborator]; Piyayotai, Dilok [Collaborator]; Camsari, Ahmet [Collaborator]; Kultursay, Hakan [Collaborator]; Mutlu, Bulent [Collaborator]; Ersanli, Murat [Collaborator]; Demirtas, Mustafa [Collaborator]; Kirma, Cevat [Collaborator]; Ural, Ertan [Collaborator]; Koldas, Lale [Collaborator]; Karpenko, Oleksandr [Collaborator]; Prokhorov, Alexander [Collaborator]; Vakaluyk, Ihor [Collaborator]; Myshanych, Halyna [Collaborator]; Reshotko, Dmytro [Collaborator]; Batushkin, Valeriy [Collaborator]; Rudenko, Leonid [Collaborator]; Kovalskyi, Ihor [Collaborator]; Kushnir, Mykola [Collaborator]; Tseluyko, Vira [Collaborator]; Mostovoy, Yuriy [Collaborator]; Stanislavchuk, Mykola [Collaborator]; Kyiak, Yulian [Collaborator]; Karpenko, Yuriy [Collaborator]; Malynovsky, Yaroslav [Collaborator]; Klantsa, Andriy [Collaborator]; Kutniy, Oles [Collaborator]; Amosova, Ekaterina [Collaborator]; Tashchuk, Viktor [Collaborator]; Leshchuk, Oleh [Collaborator]; Rishko, Mykola [Collaborator]; Kopytsya, Mykola [Collaborator]; Yagensky, Andriy [Collaborator]; Vatutin, Mykola [Collaborator]; Bagriy, Andriy [Collaborator]; Barna, Olga M [Collaborator]; Ushakov, Olexiy [Collaborator]; Dzyak, Georgiy [Collaborator]; Goloborodko, Borys [Collaborator]; Rudenko, Anatolii [Collaborator]; Trevelyan, Jasper [Collaborator]; Zaman, Azfar [Collaborator]; Lee, Kaeng [Collaborator]; Moriarty, Andrew [Collaborator]; Aggarwal, Rajesh K [Collaborator]; Clifford, Piers [Collaborator]; Wong, Yuk-Ki [Collaborator]; Iqbal, Syed M R [Collaborator]; Subkovas, Eduardas [Collaborator]; Braganza, Denise [Collaborator]; Sarkar, David [Collaborator]; Storey, Robert [Collaborator]; Griffiths, Huw [Collaborator]; Mcclure, Sam [Collaborator]; Muthusamy, Rangasamy [Collaborator]; Kurian, John [Collaborator]; Levy, Terry [Collaborator]; Barr, Craig [Collaborator]; Kadr, Honer [Collaborator]; Gerber, Robert [Collaborator]; Simaitis, Audrius [Collaborator]; Soran, Handrean [Collaborator]; Mathur, Anthony [Collaborator]; Brodison, Adrian [Collaborator]; Oliver, Richard [Collaborator]; Mudawi, Telal [Collaborator]; Reynolds, Timothy [Collaborator]; Sharman, David [Collaborator]; Butler, Rob [Collaborator]; Wilkinson, Peter [Collaborator]; Lip, Gregory Y H [Collaborator]; Halcox, Julian [Collaborator]; Vardi, Gil [Collaborator]; Baldari, Duccio [Collaborator]; Brabham, David [Collaborator]; Treasure, Charles [Collaborator]; Dahl, Charles [Collaborator]; Palmer, Bruce [Collaborator]; Wiseman, Alan [Collaborator]; Khan, Abul [Collaborator]; Puri, Sanjeev [Collaborator]; Mohart, Ann Elizabeth [Collaborator]; Ince, Carlos [Collaborator]; Flores, Enrique [Collaborator]; Wright, Scott [Collaborator]; Cheng, Shi-Chi [Collaborator]; Rosenberg, Michael [Collaborator]; Rogers, William [Collaborator]; Kosinski, Edward [Collaborator]; Forgosh, Les [Collaborator]; Waltman, Jonathan [Collaborator]; Khan, Misal [Collaborator]; Shoukfeh, Mohammad [Collaborator]; Dagher, Georges [Collaborator]; Lieber, Ira [Collaborator]; Kumar, Priya [Collaborator]; East, Cara [Collaborator]; Krichmar, Perry [Collaborator]; White, Lindsey [Collaborator]; Knickelbine, Thomas [Collaborator]; Haldis, Thomas [Collaborator]; Gillespie, Eve [Collaborator]; Suh, David [Collaborator]; Arif, Imran [Collaborator]; Akhter, Faiq [Collaborator]; Carlson, Eric [Collaborator]; D'Urso, Michael [Collaborator]; El-Ahdab, Fadi [Collaborator]; Nelson, William [Collaborator]; Harris, Barry [Collaborator]; Cohen, Steven [Collaborator]; Carter, Luther [Collaborator]; Sabatino, Kenneth [Collaborator]; Haddad, Tariq [Collaborator]; Malik, Amir [Collaborator]; Rao, Sunder [Collaborator]; Mulkay, Angel [Collaborator]; Jovin, Ion [Collaborator]; Klancke, Kim [Collaborator]; Malhotra, Vinay [Collaborator]; Devarapalli, Sai K [Collaborator]; Koren, Michael [Collaborator]; Chandna, Harish [Collaborator]; Dodds, George [Collaborator]; Janik, Matthew [Collaborator]; Moran, Joseph [Collaborator]; Sumner, Andrew [Collaborator]; Kobayashi, John [Collaborator]; Davis, William [Collaborator]; Yazdani, Shahram [Collaborator]; Pasquini, John [Collaborator]; Thakkar, Maitreya [Collaborator]; Vedere, Amarnath [Collaborator]; Leimbach, Wayne [Collaborator]; Rider, James [Collaborator]; Singh, Narendra [Collaborator]; Shah, Anil V [Collaborator]; Janosik, Denise [Collaborator]; Pepine, Carl [Collaborator]; Berman, Brett [Collaborator]; Gelormini, Joseph [Collaborator]; Daniels, Christopher [Collaborator]; Keating, Friederike [Collaborator]; Kondo, Nicholas I [Collaborator]; Shetty, Sanjay [Collaborator]; Waider, Winfried [Collaborator]; Takata, Theodore [Collaborator]; Abu-Fadel, Mazen [Collaborator]; Shah, Vipul [Collaborator]; Aggarwal, Rahul [Collaborator]; Izzo, Mark [Collaborator]; Kumar, Anil [Collaborator]; Hattler, Brack [Collaborator]; Link, Chad [Collaborator]; Bortnick, Anna [Collaborator]; Kinzfogl, George [Collaborator]; Ghitis, Arnold [Collaborator]; Larry, John [Collaborator]; Teufel, Edward [Collaborator]; Kuhlman, Peter [Collaborator]; Mclaurin, Brent [Collaborator]; Zhang, Wenwu [Collaborator]; Thew, Stephen [Collaborator]; Abbas, Jalal [Collaborator]; White, Matthew [Collaborator]; Ranadive, Nandkishore [Collaborator]; Gring, Christian [Collaborator]; Henderson, David [Collaborator]; Schuchard, Timothy [Collaborator]; Farhat, Naim [Collaborator]; Kline, Geoffrey [Collaborator]; Mahal, Sharan [Collaborator]; Whitaker, Jack [Collaborator]; Speirs, Shawn [Collaborator]; Andersen, Rolf [Collaborator]; Daboul, Nizar [Collaborator]; Horwitz, Phillip [Collaborator]; Jafar, Zubair [Collaborator]; Mcgarvey, Joseph [Collaborator]; Panchal, Vipul [Collaborator]; Voyce, Stephen [Collaborator]; Blok, Thomas [Collaborator]; Sheldon, William [Collaborator]; Azizad, Masoud M [Collaborator]; Schmalfuss, Carsten [Collaborator]; Picone, Mark [Collaborator]; Herzog, William [Collaborator]; Lindsey, Jason [Collaborator]; Nowins, Rosemary [Collaborator]; Lepor, Norman [Collaborator]; El Shahawy, Mahfouz [Collaborator]; Weintraub, Howard [Collaborator]; Irimpen, Anand [Collaborator]; May, Wade [Collaborator]; Galski, Thomas [Collaborator]; Chu, Alan [Collaborator]; Mody, Freny [Collaborator]; Hodes, Zachary [Collaborator]; Fairlamb, James [Collaborator]; Lambert, Charles [Collaborator]; Raisinghani, Ajit [Collaborator]; Abbate, Antonio [Collaborator]; King, Marilyn [Collaborator]; Carey, Charles [Collaborator]; Gerber, Jaime [Collaborator]; Younis, Liwa [Collaborator]; Park, Hyeun Tom [Collaborator]; Vidovich, Mladen [Collaborator]; Knutson, Thomas [Collaborator]; Friedman, Dennis [Collaborator]; Chaleff, Fred [Collaborator]; Loussararian, Arthur [Collaborator]; Kimmelstiel, Carey [Collaborator]; Silver, Kevin [Collaborator]; Foster, Malcolm [Collaborator]; Tonnessen, Glen [Collaborator]; Amlani, Mohamadali [Collaborator]; Wali, Andreas [Collaborator]; Malozzi, Christopher [Collaborator]; Wattanakit, Keattiyoat [Collaborator]; O'Donnell, Philip J [Collaborator]; Singal, Dinesh [Collaborator]; Jaffrani, Naseem [Collaborator]; Banuru, Sridhar [Collaborator]; Fisher, Daniel [Collaborator]; Xenakis, Mark [Collaborator]; Perlmutter, Neal [Collaborator]; Bhagwat, Ravi [Collaborator]; Strader, James [Collaborator]; Akyea-Djamson, Ayim [Collaborator]; Labroo, Ajay [Collaborator]; Lee, Kwan [Collaborator]; Marais, H John [Collaborator]; Claxton, Edmund [Collaborator]; Berk, Martin [Collaborator]; Rossi, Peter [Collaborator]; Joshi, Parag [Collaborator]; Khaira, Ajit S [Collaborator]; Kumkumian, Greg [Collaborator]; Lupovitch, Steven [Collaborator]; Purow, Joshua [Collaborator]; Welka, Stephen [Collaborator]; Hoffman, David [Collaborator]; Fischer, Stuart [Collaborator]; Soroka, Eugene [Collaborator]; Eagerton, Donald [Collaborator]; Pancholy, Samir [Collaborator]; Ray, Michael [Collaborator]; Farrar, Michael [Collaborator]; Pollock, Stewart [Collaborator]; French, William J [Collaborator]; Diamantis, Steve [Collaborator]; Gimple, Lawrence [Collaborator]; Schwartz, Steven [Collaborator]; Pereira, Edward [Collaborator]; Spriggs, Douglas [Collaborator]; Strain, Janet [Collaborator]; Vo, Anthony [Collaborator]; Chane, Majed [Collaborator]; Hall, Jason [Collaborator]; Vijay, Nampalli [Collaborator]; Lotun, Kapildeo [Collaborator]; Lester, F Martin [Collaborator]; Nahhas, Ahed [Collaborator]; Pope, Theodore [Collaborator]; Nager, Paul [Collaborator]; Vohra, Rakesh [Collaborator]; Bashir, Riyaz [Collaborator]; Ahmed, Hinan [Collaborator]; Berlowitz, Michael [Collaborator]; Fishberg, Robert [Collaborator]; Barrucco, Robert [Collaborator]; Yang, Eric [Collaborator]; Radin, Michael [Collaborator]; Sporn, Daniel [Collaborator]; Eisenberg, Steven [Collaborator]; Landzberg, Joel [Collaborator]; Mcgough, Martin [Collaborator]; Turk, Samir [Collaborator]; Schwartz, Michael [Collaborator]; Sundram, P Sandy [Collaborator]; Jain, Diwakar [Collaborator]; Zainea, Mark [Collaborator]; Bayron, Carlos [Collaborator]; Karlsberg, Ronald [Collaborator]; Lui, Henry [Collaborator]; Keen, William [Collaborator]; Westerhausen, Donald [Collaborator]; Khurana, Sandeep [Collaborator]; Agarwal, Himanshu [Collaborator]; Birchem, Jessica [Collaborator]; Penny, William [Collaborator]; Chang, Mark [Collaborator]; Gilbert, John M [Collaborator]; Chalavarya, Gopal [Collaborator]; Eaton, Charles [Collaborator]; Schmedtje, John F [Collaborator]; Christenson, Stuart [Collaborator]; Denham, Douglas [Collaborator]; Macdonell, Alexander [Collaborator]; Gibson, Paul [Collaborator]; Rahman, Aref [Collaborator]; Al Joundi, Tammam [Collaborator]; Conrad, Gary [Collaborator]; Kotha, Purushotham [Collaborator]; Love, Michael [Collaborator]; Giesler, Gregory [Collaborator]; Rubenstein, Howard [Collaborator]; Akright, Laura [Collaborator]; Schifferdecker, Branislav [Collaborator]; Krawczyk, Justine [Collaborator]; Wells, Terry [Collaborator]; Welker, James [Collaborator]; Foster, Robert [Collaborator]; Gilmore, Richard [Collaborator]; Anderson, Jay [Collaborator]; Jacoby, Douglas [Collaborator]; Harris, Bill [Collaborator]; Gardner, Geraldine [Collaborator]; Dandillaya, Ramprasad [Collaborator]; Vora, Kishor [Collaborator]; Kostis, John [Collaborator]; Hunter, John [Collaborator]; Laxson, David [Collaborator]; Ball, Eric [Collaborator]

English Study Group (Journal Article) Scientific
Published: NEW ENGLAND JOURNAL OF MEDICINE 0028-4793 1533-4406 379 (22) pp. 2097-2107 2018
  • SJR Scopus - Medicine (miscellaneous): D1
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Patients who have had an acute coronary syndrome are at high risk for recurrent ischemic cardiovascular events. We sought to determine whether alirocumab, a human monoclonal antibody to proprotein convertase subtilisin-kexin type 9 (PCSK9), would improve cardiovascular outcomes after an acute coronary syndrome in patients receiving high-intensity statin therapy.We conducted a multicenter, randomized, double-blind, placebo-controlled trial involving 18,924 patients who had an acute coronary syndrome 1 to 12 months earlier, had a low-density lipoprotein (LDL) cholesterol level of at least 70 mg per deciliter (1.8 mmol per liter), a non-high-density lipoprotein cholesterol level of at least 100 mg per deciliter (2.6 mmol per liter), or an apolipoprotein B level of at least 80 mg per deciliter, and were receiving statin therapy at a high-intensity dose or at the maximum tolerated dose. Patients were randomly assigned to receive alirocumab subcutaneously at a dose of 75 mg (9462 patients) or matching placebo (9462 patients) every 2 weeks. The dose of alirocumab was adjusted under blinded conditions to target an LDL cholesterol level of 25 to 50 mg per deciliter (0.6 to 1.3 mmol per liter). The primary end point was a composite of death from coronary heart disease, nonfatal myocardial infarction, fatal or nonfatal ischemic stroke, or unstable angina requiring hospitalization.The median duration of follow-up was 2.8 years. A composite primary end-point event occurred in 903 patients (9.5%) in the alirocumab group and in 1052 patients (11.1%) in the placebo group (hazard ratio, 0.85; 95% confidence interval [CI], 0.78 to 0.93; P<0.001). A total of 334 patients (3.5%) in the alirocumab group and 392 patients (4.1%) in the placebo group died (hazard ratio, 0.85; 95% CI, 0.73 to 0.98). The absolute benefit of alirocumab with respect to the composite primary end point was greater among patients who had a baseline LDL cholesterol level of 100 mg or more per deciliter than among patients who had a lower baseline level. The incidence of adverse events was similar in the two groups, with the exception of local injection-site reactions (3.8% in the alirocumab group vs. 2.1% in the placebo group).Among patients who had a previous acute coronary syndrome and who were receiving high-intensity statin therapy, the risk of recurrent ischemic cardiovascular events was lower among those who received alirocumab than among those who received placebo. (Funded by Sanofi and Regeneron Pharmaceuticals; ODYSSEY OUTCOMES ClinicalTrials.gov number, NCT01663402 .).
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2024-10-10 00:57