Peptidergic neurons of the Edinger–Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in humans who died by suicide

Kormos, Viktória ✉ [Kormos, Viktória (Farmakológia), author] Department of Pharmacology and Pharmacotherapy (UP / UPMS); Molecular Pharmacology Research Group (UP / SZRC); Kecskés, Angéla [Kecskés, Angéla (Molekuláris bioló...), author] Department of Pharmacology and Pharmacotherapy (UP / UPMS); Molecular Pharmacology Research Group (UP / SZRC); Farkas, József [Farkas, József (Anatómia), author] Department of Anatomy (UP / UPMS); Szentágothai Research Centre (UP); Gaszner, Tamás [Gaszner, Tamás (Idegtudomány), author] Department of Anatomy (UP / UPMS); Szentágothai Research Centre (UP); Csernus, Valér [Csernus, Valér (Neuroendokrinológia), author] Department of Anatomy (UP / UPMS); Szentágothai Research Centre (UP); Alomari, Ammar [Al-omari, Ammar (Pharmacology), author] Department of Pharmacology and Pharmacotherapy (UP / UPMS); Szentágothai Research Centre (UP); Hegedüs, Dániel [Hegedüs, Dániel (Neurobiológia, St...), author] Department of Anatomy (UP / UPMS); Department of Pharmacology and Pharmacotherapy (UP / UPMS); Molecular Pharmacology Research Group (UP / SZRC); Renner, Éva [Dobolyiné Renner, Éva (neurobiológia), author] Human Brain Tissue Bank (SU / FM / I / ASZFI_2016); Palkovits, Miklós [Palkovits, Miklós (Neuroanatómia), author] Human Brain Tissue Bank (SU / FM / I / ASZFI_2016); Zelena, Dóra [Zelena, Dóra (Neuroendokrinológia), author] Institute of Physiology (UP / UPMS); Szentágothai Research Centre (UP); Helyes, Zsuzsanna [Helyes, Zsuzsanna (Neurofarmakológia), author] Department of Pharmacology and Pharmacotherapy (UP / UPMS); Molecular Pharmacology Research Group (UP / SZRC); Pintér, Erika [Pintér, Erika (Farmakológia), author] Department of Pharmacology and Pharmacotherapy (UP / UPMS); Molecular Pharmacology Research Group (UP / SZRC); Gaszner, Balázs ✉ [Gaszner, Balázs (Neuroanatómia), author] Department of Anatomy (UP / UPMS); Szentágothai Research Centre (UP)

Fundings:

• (KA-2019-12)
• (ÚNKP-20-4- II-PTE-874)
• (KA-2021-23)
• (2017-1.2.1-NKP-2017-00002.)
• Felsőoktatási Intézményi Kiválósági Program(20765-3/2018/FEKUTSTRAT)
• “The role of neuro-inflammation in neurodegeneration: from molecules to clinics”(EFOP-3.6.2-16-2017-00008)
• (KTIA NAP 20017-1.2.1- NKP-2017-00002)
• (FK124188)
• (TKP2021-EGA-16)