https://m2.mtmt.hu/ eng 2026-09-21 19:58 JournalArticle 32639417 VALIDATED true ELKH Hereditary Cancer Research Group, Budapest, 1052, Hungary Department of Molecular Genetics, National Institute of Oncology, Budapest, 1122, Hungary Department of Laboratory Medicine, Semmelweis University, Budapest, 1085, Hungary Cited By :10 Export Date: 13 December 2023 Correspondence Address: Patocs, A.; ELKH Hereditary Cancer Research GroupHungary; email: patocs.attila@med.semmelweis-univ.hu Chemicals/CAS: axitinib, 319460-85-0; cabozantinib, 942407-59-2, 1140909-48-3, 849217-68-1; dovitinib, 804551-71-1, 915769-50-5; ethanolamine, 141-43-5; fumarate hydratase, 9032-88-6; hypoxia inducible factor proline dioxygenase; malate dehydrogenase, 9001-64-3; pazopanib, 444731-52-6, 635702-64-6; phenylethanolamine n methyltransferase, 9037-68-7; succinate dehydrogenase, 9002-02-2, 9028-10-8; sunitinib, 341031-54-7, 557795-19-4 0 false 2026-07-17T00:11:56.374+0000 2024-04-11T08:10:50.042+0000 2022-02-02T07:58:42.059+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2025-07-30T12:50:36.899+0000 2023-03-20T11:28:29.035+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 2024-04-11T08:10:50.327+0000 true 10003134 Wolf György /api/admin/10003134 Admin true 10003134 Admin 10003134 /api/admin/10003134 Wolf György true 10003134 true 2024-04-11T07:19:53.187+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Sarkadi, B. Genetics of Pheochromocytomas and Paragangliomas Determine the Therapeutical Approach true true /api/journal/10003252 REVIEWED true false 10003252 false 10003252 true 1661-6596 1422-0067 Journal FOREIGN 23 3 1450 1450 17 2022 Pheochromocytomas and paragangliomas are the most heritable endocrine tumors. In addition to the inherited mutation other driver mutations have also been identified in tumor tissues. All these genetic alterations are clustered in distinct groups which determine the pathomechanisms. Most of these tumors are benign and their surgical removal will resolve patient management. However, 5-15% of them are malignant and therapeutical possibilities for them are limited. This review provides a brief insight about the tumorigenesis associated with pheochromocytomas/paragangliomas in order to present them as potential therapeutical targets. 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(<span class="authorship-author-name">Butz Henriett</span> <span class="authorAux-mtmt"> orvostudomány</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Laboratory Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10001006"><a href="/gui2/?type=authors&mode=browse&sel=10001006" target="_blank">Patocs A. ✉ (<span class="authorship-author-name">Patócs Attila Balázs</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil">National Institute of Oncology; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Laboratory Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32639417" target="_blank">Genetics of Pheochromocytomas and Paragangliomas Determine the Therapeutical Approach</a></div> <div> <span class="journal-title">INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1661-6596">1661-6596</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1422-0067">1422-0067</a>)</span>: <span class="journal-volume">23</span> <span class="journal-issue">3</span> <span class="page"> Paper 1450. 17 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/ijms23031450" target="_blank" href="https://doi.org/10.3390/ijms23031450"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000759882300001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000759882300001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85123352602" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85123352602"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35163370" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35163370&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Inorganic Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Spectroscopy&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Computer Science Applications&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Organic Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Physical and Theoretical Chemistry&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Catalysis&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Molecular Biology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 33</span> | Independent citation: 33 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 27 | Number of citations in Scopus:&nbsp;29 | WoS/Scopus assigned:&nbsp;30 | Number of citations with DOI:&nbsp;30 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32639417&sort=publishedYear,desc&sort=title"> Number of cited publications: 5 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32639417</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="funder"> (National Tumor Biology Laboratory, NLP-17) Funder: The Hungarian National Laboratories Excellence program </div> <div class="lastModified">Last Modified: 2024.04.11. 10:10 György Wolf (MTMT Központi admin) </div> <div class="lockedBy">Centrally managed 2024.04.11. 09:19 György Wolf (MTMT Központi admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: ELKH Hereditary Cancer Research Group, Budapest, 1052, Hungary Department of Molecular Genetics, National Institute of Oncology, Budapest, 1122, Hungary Department of Laboratory Medicine, Semmelweis University, Budapest, 1085, Hungary Cited By :10 Export Date: 13 December 2023 ...</pre> </div></div>