https://m2.mtmt.hu/ hun 2026-10-23 18:48 JournalArticle 32627488 VALIDATED true Heart and Vascular Center, Semmelweis University, Városmajor utca 68, Budapest, 1122, Hungary Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest, 1089, Hungary Institute of Digital Health Sciences, Semmelweis University, Ferenc tér 15, Budapest, 1094, Hungary Cited By :8 Export Date: 29 July 2024 CODEN: BCDMB Correspondence Address: Takács, A.; Department of Genetics, Nagyvárad tér 4, Hungary; email: takacs.angela@med.semmelweis-univ.hu Chemicals/CAS: uric acid, 69-93-2; Advanced Oxidation Protein Products; Biomarkers Funding text 1: Open Access funding provided by Semmelweis University. This work was supported by the National Research, Development and Innovation Office of Hungary [NVKP-16-1-2016-0017] and by the Development of scientific workshops of medical-, health- and pharmaceutical sciences educations [EFOP-3.6.3-VEKOP-16-2017-00009]. The research was financed by the Higher Education Institutional Excellence Program of the Ministry of Human Capacities in Hungary, within the framework of the Therapeutic Development thematic program of Semmelweis University. The funder had no role in the design of this study; in the collection, analysis, and interpretation of data; or in writing the manuscript. 0 false 2026-10-22T03:07:18.663+0000 2025-12-04T11:55:28.186+0000 2022-01-27T12:54:41.946+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2025-07-14T12:43:19.044+0000 2024-02-20T09:55:23.009+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin true 10062062 2025-12-04T11:55:29.158+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Bagyura, Zsolt Level of advanced oxidation protein products is associated with subclinical atherosclerosis true true /api/journal/10014313 REVIEWED true false 10014313 false 10014313 true 1471-2261 1471-2261 Journal FOREIGN 22 1 5 5 9 2022 Background Oxidative stress is an important factor in the pathomechanism of atherosclerosis. Advanced oxidation protein products (AOPPs) are considered markers of oxidative stress. Thickening of the carotid intima-media layers indicates subclinical atherosclerosis and can be detected by carotid ultrasound. Objective Our aim was to examine the association between carotid intima-media thickness (CIMT) and the level of AOPPs. Methods Carotid duplex scans and measurements of AOPPs were performed on 476 participants of a cardiovascular population study. The presence of conventional cardiovascular risk factors was investigated with a questionnaire, physical examination, and laboratory tests. Results There was a positive correlation between maximum CIMT and the level of AOPPs only in the male population (r = 0.219, p = 0.033). Multivariate analysis has revealed that the association between AOPPs and mean or maximum CIMT was independent of cardiovascular risk factors (OR = 1.458, p = 0.004, and OR = 2.038, p < 0.001). Conclusions Among males, the elevated level of AOPPs as a marker of oxidative stress may signal the existence of early atherosclerotic alterations. 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10009579 /api/author/10009579 Dinya Elek true 10009579 true Dinya Elek true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100303878 /api/authorship/100303878 8 0.083 false false false Author 10012750 /api/author/10012750 Soós Pál true 10012750 true Soos Pal true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100303879 /api/authorship/100303879 9 0.083 false false false Author 10002997 /api/author/10002997 Szelid Zsolt László true 10002997 true Szelid Zsolt true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100303880 /api/authorship/100303880 10 0.083 false false false Author 10027592 /api/author/10027592 Láng Orsolya true 10027592 true Lang Orsolya true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100303881 /api/authorship/100303881 11 0.083 false false false Author 10015589 /api/author/10015589 Pállinger Éva true 10015589 true Pallinger Eva true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100304146 /api/authorship/100304146 12 0.0 false true Author 10000509 /api/author/10000509 Kőhidai László true 10000509 true Kohidai L true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 100303882 /api/authorship/100303882 13 0.083 false true false Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely Bela true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 20486871 /api/publicationidentifier/20486871 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1186/s12872-021-02451-2 https://doi.org/10.1186/s12872-021-02451-2 false true PublicationIdentifier 20486872 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<img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10022908"><a href="/gui2/?type=authors&mode=browse&sel=10022908" target="_blank">Bagyura Zsolt (<span class="authorship-author-name">Bagyura Zsolt</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10062490"><a href="/gui2/?type=authors&mode=browse&sel=10062490" target="_blank">Takacs Angela<sup>*</sup> ✉ (<span class="authorship-author-name">Takács Angéla</span> <span class="authorAux-mtmt"> gyógyszerésztudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10066754"><a href="/gui2/?type=authors&mode=browse&sel=10066754" target="_blank">Kiss Loretta (<span class="authorship-author-name">Kiss Loretta Zsuzsa</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10026900"><a href="/gui2/?type=authors&mode=browse&sel=10026900" target="_blank">Dosa Edit (<span class="authorship-author-name">Dósa Edit</span> <span class="authorAux-mtmt"> radiológus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10072714"><a href="/gui2/?type=authors&mode=browse&sel=10072714" target="_blank">Vadas Reka (<span class="authorship-author-name">Vadas Réka</span> <span class="authorAux-mtmt"> Gyermekgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065592"><a href="/gui2/?type=authors&mode=browse&sel=10065592" target="_blank">Nguyen Tin Dat (<span class="authorship-author-name">Nguyen Tin Dat</span> <span class="authorAux-mtmt"> Szív és érbetegségek</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009579"><a href="/gui2/?type=authors&mode=browse&sel=10009579" target="_blank">Dinya Elek (<span class="authorship-author-name">Dinya Elek</span> <span class="authorAux-mtmt"> Orvosi biometria</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Egészségügyi Közszolgálati Kar">EKK</span>/Digitális Egészségtudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012750"><a href="/gui2/?type=authors&mode=browse&sel=10012750" target="_blank">Soos Pal (<span class="authorship-author-name">Soós Pál</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002997"><a href="/gui2/?type=authors&mode=browse&sel=10002997" target="_blank">Szelid Zsolt (<span class="authorship-author-name">Szelid Zsolt László</span> <span class="authorAux-mtmt"> kardiológia, sportkardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Kardiológia Központ - Kardiológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10027592"><a href="/gui2/?type=authors&mode=browse&sel=10027592" target="_blank">Lang Orsolya (<span class="authorship-author-name">Láng Orsolya</span> <span class="authorAux-mtmt"> sejtbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10015589"><a href="/gui2/?type=authors&mode=browse&sel=10015589" target="_blank">Pallinger Eva (<span class="authorship-author-name">Pállinger Éva</span> <span class="authorAux-mtmt"> Immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000509"><a href="/gui2/?type=authors&mode=browse&sel=10000509" target="_blank">Kohidai L<sup>**</sup> (<span class="authorship-author-name">Kőhidai László</span> <span class="authorAux-mtmt"> Elméleti orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Intézet">I</span>/Genetikai, Sejt- és Immunbiológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Bela (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Sportorvostan Tanszék</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32627488" target="_blank">Level of advanced oxidation protein products is associated with subclinical atherosclerosis</a></div> <div> <span class="journal-title">BMC CARDIOVASCULAR DISORDERS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1471-2261">1471-2261</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1471-2261">1471-2261</a>)</span>: <span class="journal-volume">22</span> <span class="journal-issue">1</span> <span class="page"> Paper 5. 9 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1186/s12872-021-02451-2" target="_blank" href="https://doi.org/10.1186/s12872-021-02451-2"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000740235400001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000740235400001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85122709688" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85122709688"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34996369" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34996369&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 27</span> | Független: 27 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 24 | Scopus jelölt:&nbsp;25 | WoS/Scopus jelölt:&nbsp;27 | DOI jelölt:&nbsp;26 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32627488&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32627488</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="funder"> National Heart Program(NVKP-16-1-2016-0017) Támogató: NKFIH, (Open access funding of Semmelweis University), Az orvos-, egészségtudományi- és gyógyszerészképzés tudományos műhelyeinek fejlesztése(EFOP-3.6.3-VEKOP-16-2017-00009) Támogató: EFOP-VEKOP </div> <div class="lastModified">Utolsó módosítás: 2025.12.04. 12:55 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Heart and Vascular Center, Semmelweis University, Városmajor utca 68, Budapest, 1122, Hungary Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad tér 4, Budapest, 1089, Hungary Institute of Digital Health Sciences, Semmelweis University, Ferenc tér 15, Budapest, 1094, Hungary Cited By :8 ...</pre> </div></div>