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W J Guan 2020: Clinical characteristics of coronavirus disease 2019 in China., N Engl J Med, 382, p. 1708, DOI: 10.1056/NEJMoa2002032 1 10.1056/NEJMoa2002032 false true Reference 26977989 /api/reference/26977989 2. F Zhou 2020: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study., Lancet, 395, p. 1054, DOI: 10.1016/S0140-6736(20)30566-3 2 10.1016/S0140-6736(20)30566-3 false true Reference 26977990 /api/reference/26977990 3. G Chen 2020: Clinical and immunological features of severe and moderate coronavirus disease 2019., J Clin Invest, 130, p. 2620, DOI: 10.1172/JCI137244 3 10.1172/JCI137244 false true Reference 26977991 /api/reference/26977991 4. J B Moore 2020: Cytokine release syndrome in severe COVID-19., Science, 368, p. 473, DOI: 10.1126/science.abb8925 4 10.1126/science.abb8925 false true Reference 26977992 /api/reference/26977992 5. J Helms 2020: High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study., Intensive Care Med, 46, p. 1089, DOI: 10.1007/s00134-020-06062-x 5 10.1007/s00134-020-06062-x false true Reference 26977993 /api/reference/26977993 6. M Levi 2020: Coagulation abnormalities and thrombosis in patients with COVID-19., Lancet Haematol, 7, p. e438, DOI: 10.1016/S2352-3026(20)30145-9 6 10.1016/S2352-3026(20)30145-9 false true Reference 26977994 /api/reference/26977994 7. R Escher 2020: Severe COVID-19 infection associated with endothelial activation., Thromb Res, 190, p. 62, DOI: 10.1016/j.thromres.2020.04.014 7 10.1016/j.thromres.2020.04.014 false true Reference 26977995 /api/reference/26977995 8. G Goshua 2020: Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study., Lancet Haematol, 7, p. e575, DOI: 10.1016/S2352-3026(20)30216-7 8 10.1016/S2352-3026(20)30216-7 false true Reference 26977996 /api/reference/26977996 9. A Rauch 2020: Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19., J Thromb Haemost, 18, p. 2942, DOI: 10.1111/jth.15067 9 10.1111/jth.15067 false true Reference 26977997 /api/reference/26977997 10. R Escher 2020: ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients., Thromb Res, 192, p. 174, DOI: 10.1016/j.thromres.2020.05.032 10 10.1016/j.thromres.2020.05.032 false true Reference 26977998 /api/reference/26977998 11. M Bazzan 2020: Low ADAMTS 13 plasma levels are predictors of mortality in COVID-19 patients., Intern Emerg Med, 15, p. 861, DOI: 10.1007/s11739-020-02394-0 11 10.1007/s11739-020-02394-0 false true Reference 26977999 /api/reference/26977999 12. A Huisman 2020: Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS-CoV-2., Int J Lab Hematol, 42, p. e211, DOI: 10.1111/ijlh.13244 12 10.1111/ijlh.13244 false true Reference 26978000 /api/reference/26978000 13. N Martinelli 2020: A relative ADAMTS13 deficiency supports the presence of a secondary microangiopathy in COVID 19., Thromb Res, 193, p. 170, DOI: 10.1016/j.thromres.2020.07.034 13 10.1016/j.thromres.2020.07.034 false true Reference 26978001 /api/reference/26978001 14. G L Tiscia 2020: Reduction of ADAMTS13 levels predicts mortality in SARS-CoV-2 patients., TH Open, 4, p. e203, DOI: 10.1055/s-0040-1716379 14 10.1055/s-0040-1716379 false true Reference 26978002 /api/reference/26978002 15. M Delrue 2021: von Willebrand factor/ADAMTS13 axis and venous thromboembolism in moderate-to-severe COVID-19 patients., Br J Haematol, 192, p. 1097, DOI: 10.1111/bjh.17216 15 10.1111/bjh.17216 false true Reference 26978003 /api/reference/26978003 16. I Mancini 2021: The ADAMTS13-von Willebrand factor axis in COVID-19 patients., J Thromb Haemost, 19, p. 513, DOI: 10.1111/jth.15191 16 10.1111/jth.15191 false true Reference 26978004 /api/reference/26978004 17. E J Favaloro 2021: Increased VWF and decreased ADAMTS-13 in COVID-19: creating a milieu for (micro)thrombosis., Semin Thromb Hemost, 47, p. 400, DOI: 10.1055/s-0041-1727282 17 10.1055/s-0041-1727282 false true Reference 26978005 /api/reference/26978005 18. A Philippe 2021: Circulating Von Willebrand factor and high molecular weight multimers as markers of endothelial injury predict COVID-19 in-hospital mortality., Angiogenesis, 24, p. 505, DOI: 10.1007/s10456-020-09762-6 18 10.1007/s10456-020-09762-6 false true Reference 26978006 /api/reference/26978006 19. M Rodríguez Rodríguez 2021: Increased von Willebrand factor antigen and low ADAMTS13 activity are related to poor prognosis in covid-19 patients., Int J Lab Hematol, 43, p. O152, DOI: 10.1111/ijlh.13476 19 10.1111/ijlh.13476 false true Reference 26978007 /api/reference/26978007 20. J M Sweeney 2020: Evidence for secondary thrombotic microangiopathy in COVID-19., medRxiv, DOI: 10.1101/2020.10.20.20215608 20 10.1101/2020.10.20.20215608 false true Reference 26978008 /api/reference/26978008 21. F A von Meijenfeldt 2020: Prothrombotic changes in patients with COVID-19 are associated with disease severity and mortality., Res Pract Thromb Haemost, 5, p. 132, DOI: 10.1002/rth2.12462 21 10.1002/rth2.12462 false true Reference 26978009 /api/reference/26978009 22. M Cugno 2021: Complement activation and endothelial perturbation parallel COVID-19 severity and activity., J Autoimmun, 116, p. 102560, DOI: 10.1016/j.jaut.2020.102560 22 10.1016/j.jaut.2020.102560 false true Reference 26978010 /api/reference/26978010 23. S E Ward 2021: Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation., Br J Haematol, 192, p. 714, DOI: 10.1111/bjh.17273 23 10.1111/bjh.17273 false true Reference 26978011 /api/reference/26978011 24. Z Varga 2020: Endothelial cell infection and endotheliitis in COVID-19., Lancet, 395, p. 1417, DOI: 10.1016/S0140-6736(20)30937-5 24 10.1016/S0140-6736(20)30937-5 false true Reference 26978012 /api/reference/26978012 25. K Neubauer 2021: Endothelial cells and coagulation., Cell Tissue Res, DOI: 10.1007/s00441-021-03471-2 25 10.1007/s00441-021-03471-2 false true Reference 26978013 /api/reference/26978013 26. K N Ekdahl 2016: Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation., Immunol Rev, 274, p. 245, DOI: 10.1111/imr.12471 26 10.1111/imr.12471 false true Reference 26978014 /api/reference/26978014 27. A H de Nooijer 2021: Complement activation in the disease course of coronavirus disease 2019 and its effects on clinical outcomes., J Infect Dis, 223, p. 214, DOI: 10.1093/infdis/jiaa646 27 10.1093/infdis/jiaa646 false true Reference 26978015 /api/reference/26978015 28. J C Holter 2020: Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients., Proc Natl Acad Sci U S A, 117, p. 25018, DOI: 10.1073/pnas.2010540117 28 10.1073/pnas.2010540117 false true Reference 26978016 /api/reference/26978016 29. G Sinkovits 2021: Complement overactivation and consumption predicts in-hospital mortality in SARS-CoV-2 infection., Front Immunol, 12, p. 663187, DOI: 10.3389/fimmu.2021.663187 29 10.3389/fimmu.2021.663187 false true Reference 26978017 /api/reference/26978017 30. P A Ward 2010: The harmful role of c5a on innate immunity in sepsis., J Innate Immun, 2, p. 439, DOI: 10.1159/000317194 30 10.1159/000317194 false true Reference 26978018 /api/reference/26978018 31. T Gombos 2009: Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure., Thromb Haemost, 102, p. 573, DOI: 10.1160/TH09-01-0036 31 10.1160/TH09-01-0036 false true Reference 26978019 /api/reference/26978019 32. J Czúcz 2012: Endothelial cell function in patients with hereditary angioedema: elevated soluble E-selectin level during inter-attack periods., J Clin Immunol, 32, p. 61, DOI: 10.1007/s10875-011-9606-7 32 10.1007/s10875-011-9606-7 false true Reference 26978020 /api/reference/26978020 33. S Maharaj 2021: Thrombotic thrombocytopenic purpura (TTP) response following COVID-19 infection: Implications for the ADAMTS-13-von Willebrand factor axis., J Thromb Haemost, 19, p. 1130, DOI: 10.1111/jth.15230 33 10.1111/jth.15230 false true Reference 26978021 /api/reference/26978021 34. A Blasi 2020: In vitro hypercoagulability and ongoing in vivo activation of coagulation and fibrinolysis in COVID-19 patients on anticoagulation., J Thromb Haemost, 18, p. 2646, DOI: 10.1111/jth.15043 34 10.1111/jth.15043 false true Reference 26978022 /api/reference/26978022 35. B M Henry 2021: ADAMTS13 activity to von Willebrand factor antigen ratio predicts acute kidney injury in patients with COVID-19: evidence of SARS-CoV-2 induced secondary thrombotic microangiopathy., Int J Lab Hematol, 43, p. 129, DOI: 10.1111/ijlh.13415 35 10.1111/ijlh.13415 false true Reference 26978023 /api/reference/26978023 36. R De Cristofaro 2021: Marked von Willebrand factor and factor VIII elevations in severe acute respiratory syndrome coronavirus-2-positive, but not severe acute respiratory syndrome coronavirus-2-negative, pneumonia: a case-control study., Blood Coagul Fibrinolysis, 32, p. 285, DOI: 10.1097/MBC.0000000000000998 36 10.1097/MBC.0000000000000998 false true Reference 26978024 /api/reference/26978024 37. B S Joly 2021: Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients., J Thromb Haemost, 19, p. 2193, DOI: 10.1111/jth.15445 37 10.1111/jth.15445 false true Reference 26978025 /api/reference/26978025 38. A AN Doevelaar 2021: von Willebrand factor multimer formation contributes to immunothrombosis in coronavirus disease 2019., Crit Care Med, 49, p. e512, DOI: 10.1097/CCM.0000000000004918 38 10.1097/CCM.0000000000004918 false true Reference 26978026 /api/reference/26978026 39. T Pascreau 2021: ADAMTS 13 deficiency is associated with abnormal distribution of von Willebrand factor multimers in patients with COVID-19., Thromb Res, 204, p. 138, DOI: 10.1016/j.thromres.2021.02.008 39 10.1016/j.thromres.2021.02.008 false true Reference 26978027 /api/reference/26978027 40. D J Pinsky 1996: Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation., J Clin Invest, 97, p. 493, DOI: 10.1172/JCI118440 40 10.1172/JCI118440 false true Reference 26978028 /api/reference/26978028 41. D A Bashir 2021: Secretion of von Willebrand factor and suppression of ADAMTS-13 activity by markedly high concentration of ferritin., Clin Appl Thromb Hemost, 27, p. 1076029621992128, DOI: 10.1177/1076029621992128 41 10.1177/1076029621992128 false true Reference 26978029 /api/reference/26978029 42. B Tomar 2020: Neutrophils and neutrophil extracellular traps drive necroinflammation in COVID-19., Cells, 9, p. E1383, DOI: 10.3390/cells9061383 42 10.3390/cells9061383 false true Reference 26978030 /api/reference/26978030 43. Y Zuo 2020: Neutrophil extracellular traps in COVID-19., JCI Insight, 5, p. 138999 43 false true Reference 26978031 /api/reference/26978031 44. J Yang 2020: Insights into immunothrombosis: the interplay among neutrophil extracellular trap, von Willebrand factor, and ADAMTS13., Front Immunol, 11, p. 610696, DOI: 10.3389/fimmu.2020.610696 44 10.3389/fimmu.2020.610696 false true Reference 26978032 /api/reference/26978032 45. N Sorvillo 2019: Plasma peptidylarginine deiminase IV promotes VWF-platelet string formation and accelerates thrombosis after vessel injury., Circ Res, 125, p. 507, DOI: 10.1161/CIRCRESAHA.118.314571 45 10.1161/CIRCRESAHA.118.314571 false true Reference 26978033 /api/reference/26978033 46. Y Wang 2015: Hypochlorous acid generated by neutrophils inactivates ADAMTS13: an oxidative mechanism for regulating ADAMTS13 proteolytic activity during inflammation., J Biol Chem, 290, p. 1422, DOI: 10.1074/jbc.M114.599084 46 10.1074/jbc.M114.599084 false true Reference 26978034 /api/reference/26978034 47. V G Pillai 2016: Human neutrophil peptides inhibit cleavage of von Willebrand factor by ADAMTS13: a potential link of inflammation to TTP., Blood, 128, p. 110, DOI: 10.1182/blood-2015-12-688747 47 10.1182/blood-2015-12-688747 false true Reference 26978035 /api/reference/26978035 48. S E Ward 2021: ADAMTS13 regulation of VWF multimer distribution in severe COVID-19., J Thromb Haemost, 19, p. 1914, DOI: 10.1111/jth.15409 48 10.1111/jth.15409 false true Reference 26978036 /api/reference/26978036 49. J F Dong 2002: ADAMTS-13 rapidly cleaves newly secreted ultralarge von Willebrand factor multimers on the endothelial surface under flowing conditions., Blood, 100, p. 4033, DOI: 10.1182/blood-2002-05-1401 49 10.1182/blood-2002-05-1401 false true Reference 26978037 /api/reference/26978037 50. S Bettoni 2017: Interaction between multimeric von Willebrand factor and complement: a fresh look to the pathophysiology of microvascular thrombosis., J Immunol, 199, p. 1021, DOI: 10.4049/jimmunol.1601121 50 10.4049/jimmunol.1601121 false true Reference 26978038 /api/reference/26978038 51. C Magro 2020: Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases., Transl Res, 220, p. 1, DOI: 10.1016/j.trsl.2020.04.007 51 10.1016/j.trsl.2020.04.007 false true Reference 26978039 /api/reference/26978039 52. M Cugno 2020: Complement activation in patients with COVID-19: a novel therapeutic target., J Allergy Clin Immunol, 146, p. 215, DOI: 10.1016/j.jaci.2020.05.006 52 10.1016/j.jaci.2020.05.006 false true Reference 26978040 /api/reference/26978040 53. M Morigi 2011: Alternative pathway activation of complement by Shiga toxin promotes exuberant C3a formation that triggers microvascular thrombosis., J Immunol, 187, p. 172, DOI: 10.4049/jimmunol.1100491 53 10.4049/jimmunol.1100491 false true Reference 26978041 /api/reference/26978041 54. K Ikeda 1997: C5a induces tissue factor activity on endothelial cells., Thromb Haemost, 77, p. 394, DOI: 10.1055/s-0038-1655974 54 10.1055/s-0038-1655974 false true Reference 26978042 /api/reference/26978042 55. F Tedesco 1997: The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity., J Exp Med, 185, p. 1619, DOI: 10.1084/jem.185.9.1619 55 10.1084/jem.185.9.1619 false true Reference 26978043 /api/reference/26978043 56. E M Conway 2012: Thrombomodulin and its role in inflammation., Semin Immunopathol, 34, p. 107, DOI: 10.1007/s00281-011-0282-8 56 10.1007/s00281-011-0282-8 false true Reference 26978044 /api/reference/26978044 57. A Klos 2009: The role of the anaphylatoxins in health and disease., Mol Immunol, 46, p. 2753, DOI: 10.1016/j.molimm.2009.04.027 57 10.1016/j.molimm.2009.04.027 false true Reference 26978045 /api/reference/26978045 58. C Kawecki 2017: von Willebrand factor and inflammation., J Thromb Haemost, 15, p. 1285, DOI: 10.1111/jth.13696 58 10.1111/jth.13696 false true Reference 26978046 /api/reference/26978046 59. P Skendros 2020: Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis., J Clin Invest, 130, p. 6151, DOI: 10.1172/JCI141374 59 10.1172/JCI141374 false true Reference 26978047 /api/reference/26978047 60. A Bonaventura 2021: Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19., Nat Rev Immunol, 21, p. 319, DOI: 10.1038/s41577-021-00536-9 60 10.1038/s41577-021-00536-9 false true /api/publication/32616895 Sinkovits György et al. Associations between the von Willebrand Factor—ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality. (2022) THROMBOSIS AND HAEMOSTASIS 0340-6245 2567-689X 122 2 240-256<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10060721"><a href="/gui2/?type=authors&mode=browse&sel=10060721" target="_blank">Sinkovits György ✉ (<span class="authorship-author-name">Sinkovits György</span> <span class="authorAux-mtmt"> orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10059803"><a href="/gui2/?type=authors&mode=browse&sel=10059803" target="_blank">Réti Marienn (<span class="authorship-author-name">Réti Marienn Györgyi</span> <span class="authorAux-mtmt"> Hematológia, transzfuziológia, belgyógyászat</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012282"><a href="/gui2/?type=authors&mode=browse&sel=10012282" target="_blank">Müller Veronika (<span class="authorship-author-name">Müller Veronika</span> <span class="authorAux-mtmt"> Pulmonológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pulmonológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024639"><a href="/gui2/?type=authors&mode=browse&sel=10024639" target="_blank">Iványi Zsolt (<span class="authorship-author-name">Iványi Zsolt</span> <span class="authorAux-mtmt"> Aneszteziológia intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Aneszteziológiai és Intenzív Terápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024202"><a href="/gui2/?type=authors&mode=browse&sel=10024202" target="_blank">Gál János (<span class="authorship-author-name">Gál János</span> <span class="authorAux-mtmt"> Aneszteziológia és intenzív terápia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Aneszteziológiai és Intenzív Terápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10066903"><a href="/gui2/?type=authors&mode=browse&sel=10066903" target="_blank">Gopcsa László (<span class="authorship-author-name">Gopcsa László</span> <span class="authorAux-mtmt"> Belgyógyászat, hematológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10059885"><a href="/gui2/?type=authors&mode=browse&sel=10059885" target="_blank">Reményi Péter (<span class="authorship-author-name">Reményi Péter</span> <span class="authorAux-mtmt"> Belgyógyászat, hematológia, infektológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szathmáry Beáta </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10036670"><a href="/gui2/?type=authors&mode=browse&sel=10036670" target="_blank">Lakatos Botond (<span class="authorship-author-name">Lakatos Botond</span> <span class="authorAux-mtmt"> Orvostudomány, infektologia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Szlávik János </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bobek Ilona </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10083743"><a href="/gui2/?type=authors&mode=browse&sel=10083743" target="_blank">Prohászka Zita Z. (<span class="authorship-author-name">Prohászka Z. Zita</span> <span class="authorAux-mtmt"> klinikai orvostudományok</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023872"><a href="/gui2/?type=authors&mode=browse&sel=10023872" target="_blank">Förhécz Zsolt (<span class="authorship-author-name">Förhécz Zsolt</span> <span class="authorAux-mtmt"> Kardiológia, belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10048389"><a href="/gui2/?type=authors&mode=browse&sel=10048389" target="_blank">Mező Blanka (<span class="authorship-author-name">Mező Blanka</span> <span class="authorAux-mtmt"> Immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Belgyógyászati és Hematológiai Klinika">BHK</span>/MTA-SE Immunológiai és Hematológiai Kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023983"><a href="/gui2/?type=authors&mode=browse&sel=10023983" target="_blank">Csuka Dorottya (<span class="authorship-author-name">Csuka Dorottya</span> <span class="authorAux-mtmt"> Humán molekuláris genetika és immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10077893"><a href="/gui2/?type=authors&mode=browse&sel=10077893" target="_blank">Hurler Lisa (<span class="authorship-author-name">Hurler Lisa</span> <span class="authorAux-mtmt"> Medical Biology</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040542"><a href="/gui2/?type=authors&mode=browse&sel=10040542" target="_blank">Kajdácsi Erika (<span class="authorship-author-name">Kajdácsi Erika</span> <span class="authorAux-mtmt"> immunológia, sejtbiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000203"><a href="/gui2/?type=authors&mode=browse&sel=10000203" target="_blank">Cervenak László (<span class="authorship-author-name">Cervenak László</span> <span class="authorAux-mtmt"> Immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10076443"><a href="/gui2/?type=authors&mode=browse&sel=10076443" target="_blank">Kiszel Petra (<span class="authorship-author-name">Kiszel Petra</span> <span class="authorAux-mtmt"> biológus</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Belgyógyászati és Hematológiai Klinika">BHK</span>/MTA-SE Immunológiai és Hematológiai Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10015319"><a href="/gui2/?type=authors&mode=browse&sel=10015319" target="_blank">Masszi Tamás (<span class="authorship-author-name">Masszi Tamás</span> <span class="authorAux-mtmt"> belgyógyászat, hematológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10034838"><a href="/gui2/?type=authors&mode=browse&sel=10034838" target="_blank">Vályi-Nagy István^** (<span class="authorship-author-name">Vályi-Nagy István</span> <span class="authorAux-mtmt"> Hematológia, belgyógyászat, onkológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000530"><a href="/gui2/?type=authors&mode=browse&sel=10000530" target="_blank">Prohászka Zoltán (<span class="authorship-author-name">Prohászka Zoltán</span> <span class="authorAux-mtmt"> Immunológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Belgyógyászati és Hematológiai Klinika">BHK</span>/MTA-SE Immunológiai és Hematológiai Kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Belgyógyászati és Hematológiai Klinika</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32616895" target="_blank">Associations between the von Willebrand Factor—ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality</a></div> <div> <span class="journal-title">THROMBOSIS AND HAEMOSTASIS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0340-6245">0340-6245</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2567-689X">2567-689X</a>)</span>: <span class="journal-volume">122</span> <span class="journal-issue">2</span> <span class="page"> pp 240-256 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1055/s-0041-1740182" target="_blank" href="https://doi.org/10.1055/s-0041-1740182"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000745314100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000745314100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85123945409" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85123945409"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="35062036" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35062036&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="https://www.scopus.com/pages/publications/85123945409?origin=resultslist" target="_blank" href="https://www.scopus.com/pages/publications/85123945409?origin=resultslist"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Hematology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 20</span> | Független: 18 | Függő: 2 | Nem jelölt: 0 | WoS jelölt: 18 | Scopus jelölt:&nbsp;20 | WoS/Scopus jelölt:&nbsp;20 | DOI jelölt:&nbsp;20 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32616895&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32616895</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (KH130355), (2020-1.1.6-JOVO-2021-00013), (PPD2018-016/2018) </div> <div class="lastModified">Utolsó módosítás: 2023.09.02. 15:49 Milánkovics Róbert (PTE ÁOK admin 4) </div> <div class="lockedBy">Központi kezelésű 2024.10.17. 18:18 Ladányi Gusztáv (MTMT API user, admin) Kériné Tornyi Katalin (MTMT ellenőrzés admin5) </div> <pre class="comment" style="margin-top: 0; 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