https://m2.mtmt.hu/ hun 2026-10-25 07:03 JournalArticle 32552784 VALIDATED true Funding Agency and Grant Number: IBSA International (Lugano, Switzerland) Funding text: The publication of this article was supported by a nonconditioning grant from IBSA International (Lugano, Switzerland). 0 false 2026-10-22T00:45:41.456+0000 2022-01-05T10:46:13.423+0000 2021-12-29T09:38:06.072+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2024-03-01T02:45:26.150+0000 2021-12-29T09:42:07.673+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Migliore, Alberto Systematic Literature Review and Expert Opinion for the Use of Viscosupplementation with Hyaluronic Acid in Different Localizations of Osteoarthritis true true /api/journal/10081265 REVIEWED true false 10081265 false 10081265 true 1179-1462 1179-1462 Journal 13 255 273 255 19 2021 Osteoarthritis (OA) is a significant cause of disability. Considering the increasing diffusion of the viscosupplementation (VS) with hyaluronic acid (HA), the International Symposium Intra Articular Treatment (ISIAT) appointed a Technical Expert Panel (TEP) to identify the criteria for successful VS with a specific HA in OA; this through a systematic literature review (SLR), performed following the PRISMA guidelines interrogating Medline, Embase, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Grey Matters and American College of Rheumatology (ACR/EULAR) databases and the opinion of international experts. The research included only studies on adults and humans without limitations of language or time of publication. Researchers extracted both quantitative and qualitative data from each study. Mixed Methods Appraisal Tool (MMAT) was used to perform quality analysis for the level of evidence. The SLR retrieved 385 papers, 25 of which were suitable for the analysis. The TEP focused on the different formulations of the product Sinovial (R) [HA 0.8%, HA 1.6%, HA 2%, 800-1200 kDa, HA 3.2% (1400-2100 kDa/65-110 kDa)]. The choice was due to the vast amount of evidence available. The TEP weighed the evidence in two rounds of a Delphi survey; the results, and any disagreement, were discussed in a final session. Three domains were considered: 1) the patients' characteristics associated with the best results; 2) the contraindications and the conditions linked to increased risk of failure; 3) the clinical conditions in which VS is considered appropriate. The TEP concluded that VS with HA is safe and effective in the treatment of knee and hip OA of grades I to III and that it is possible to undertake VS in other situations (eg grade IV Kellgren-Lawrence - KL); a comprehensive examination of the patient should be performed before the procedure. 2021 true true true false false NONE 2026-10-22 false 22 0 22 19 0 22 20 22 5 22 22 19 19 19 3 0 22 19 22 19 0 0 0 Folyóiratcikk Journal Article 24 22 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció 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Raveendhara R. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99777754 /api/authorship/99777754 5 0.071428575 false false false Blicharski Tomasz true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99777755 /api/authorship/99777755 6 0.071428575 false false false Diracoglu Demirhan true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99777756 /api/authorship/99777756 7 0.071428575 false false false Georgiadis Athanasios true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99777757 /api/authorship/99777757 8 0.071428575 false false false Hamoud Hesham true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99777758 /api/authorship/99777758 9 0.071428575 false false false Martusevich Natalia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true 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true Keyword 1203193 /api/keyword/1203193 true 1203193 true Keyword 2088643 /api/keyword/2088643 true true Keyword 2549921 /api/keyword/2549921 true true SjrRating 11232198 /api/sjrrating/11232198 100 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2732 /api/classificationexternal/2732 true 2732 true Q2 DIRECT true true /api/publication/32552784 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Migliore Alberto ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gigliucci Gianfranco </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Alekseeva Lyudmila </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bannuru Raveendhara R. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Blicharski Tomasz </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Diracoglu Demirhan </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Georgiadis Athanasios </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hamoud Hesham </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Martusevich Natalia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Cerinic Marco Matucci </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Perduk Jan </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10036891"><a href="/gui2/?type=authors&mode=browse&sel=10036891" target="_blank">Szerb Imre (<span class="authorship-author-name">Szerb Imre</span> <span class="authorAux-mtmt"> ortopédia-traumatológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Traumatológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Trc Tomag </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Chevalier Xavier </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32552784" target="_blank">Systematic Literature Review and Expert Opinion for the Use of Viscosupplementation with Hyaluronic Acid in Different Localizations of Osteoarthritis</a></div> <div> <span class="journal-title">ORTHOPEDIC RESEARCH AND REVIEWS</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1179-1462">1179-1462</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1179-1462">1179-1462</a>)</span>: <span class="journal-volume">13</span> <span class="page"> pp 255-273 </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.2147/ORR.S336185" target="_blank" href="https://doi.org/10.2147/ORR.S336185"> DOI </a> </span> <span class="id identifier 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class="citingPub-count">Nyilvános idéző összesen: 22</span> | Független: 19 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 22 | Scopus jelölt:&nbsp;5 | WoS/Scopus jelölt:&nbsp;22 | DOI jelölt:&nbsp;20 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32552784</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Összefoglaló cikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2022.01.05. 11:46 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: IBSA International (Lugano, Switzerland) Funding text: The publication of this article was supported by a nonconditioning grant from IBSA International (Lugano, Switzerland).</pre> </div></div>