Safety and efficacy of avalglucosidase alfa versus alglucosidase alfa in patients with late-onset Pompe disease (COMET): a phase 3, randomised, multicentre trial

Diaz-Manera, Jordi ✉; S Kishnani, Priya*; Kushlaf, Hani; Ladha, Shafeeq; Mozaffar, Tahseen; Straub, Volker; Toscano, Antonio; T van der Ploeg, Ans; I Berger, Kenneth; R Clemens, Paula; Chien, Yin-Hsiu; W Day, John; Illarioshkin, Sergey; Roberts, Mark; Attarian, Shahram; Lindolfo Borges, Joao; Bouhour, Francoise; Chul Choi, Young; Erdem-Ozdamar, Sevim; Goker-Alpan, Ozlem; Kostera-Pruszczyk, Anna; An Haack, Kristina; Hug, Christopher; Huynh-Ba, Olivier; Johnson, Judith; Thibault, Nathan; Zhou, Tianyue; M Dimachkie, Mazen**; Schoser, Benedikt; Investigator Group, COMET [Collaborative Organization]; Behin, Anthony [Collaborator]; Boentert, Matthias [Collaborator]; Carvalho, Gerson [Collaborator]; Chahin, Nizar [Collaborator]; Charrow, Joel [Collaborator]; Deegan, Patrick [Collaborator]; Durmus Tekce, Hacer [Collaborator]; Duval, Fanny [Collaborator]; Genge, Angela [Collaborator]; Gutmann, Ludwig [Collaborator]; D Henderson, Robert [Collaborator]; B Hennermann, Julia [Collaborator]; Hiwot, Tarekegn [Collaborator]; Hughes, Derralynn [Collaborator]; Karaa, Amel [Collaborator]; Karam, Chafic [Collaborator]; Kautzky-Willer, Alexandra [Collaborator]; Komaki, Hirofumi [Collaborator]; Laforet, Pascal [Collaborator]; Longo, Nicola [Collaborator]; Malinova, Vera [Collaborator]; Maré, Ricardo [Collaborator]; Maxit, Clarisa [Collaborator]; Mengel, Eugen [Collaborator]; Gualtiero Moggio, Maurizio [Collaborator]; Molnár, Mária Judit [Molnár, Mária Judit (Neurológia), Collaborator] Genomic Medicine and the Institute of Rare Dise... (SU / FM / I); Enrica Mongini, Tiziana [Collaborator]; Nadaj-Pakleza, Aleksandra [Collaborator]; Nascimento Osorio, Andres [Collaborator]; Noury, Jean-Baptiste [Collaborator]; Souza Bulle Oliveira, Acary [Collaborator]; Parman, Yesim [Collaborator]; Pena, Loren [Collaborator]; Remiche, Gauthier [Collaborator]; Sciacco, Monica [Collaborator]; B Shieh, Perry [Collaborator]; Smith, Cheryl [Collaborator]; Stulnig, Thomas [Collaborator]; Taithe, Frederic [Collaborator]; Tard, Céline [Collaborator]; Tarnopolsky, Mark [Collaborator]; Vorgerd, Matthias [Collaborator]; Whitley, Chester [Collaborator]; Young, Peter [Collaborator]; Alonso-Pérez, Jorge [Collaborator]; Altemus, Patricia [Collaborator]; Aubé-Nathier, Anne-Catherine [Collaborator]; B Avelar, Jennifer [Collaborator]; Bailey, Carrie [Collaborator]; Ebru Bekircan-Kurt, Can [Collaborator]; Billy, Jenny [Collaborator]; Boschi, Silvia [Collaborator]; E Brown, Kathryn [Collaborator]; Carrera Garcia, Laura [Collaborator]; Chase, Lauren [Collaborator]; Cirne, Hamilton [Collaborator]; Danjoux, Loïc [Collaborator]; Davion, Jean-Baptiste [Collaborator]; DeArmey, Stephanie [Collaborator]; Fedotova, Ekaterina [Collaborator]; Gandolfo, Eve [Collaborator]; Grosz, Zoltan [Grosz, Zoltán (Neurológia), Collaborator] Genomic Medicine and the Institute of Rare Dise... (SU / FM / I); Guellec, Dewi [Collaborator]; Guettsches, Anne-Katrin [Collaborator]; Guglieri, Michela [Collaborator]; Hatcher, Erin [Collaborator]; Helms, Sina [Collaborator]; Hufgard-Leitner, Miriam [Collaborator]; A. Klyushnikov, Sergey [Collaborator]; Langton, Jacqui [Collaborator]; Linková, Lenka [Collaborator]; Mavroudakis, Nicolas [Collaborator]; Mazurová, Stella [Collaborator]; Mori, Madoka [Collaborator]; Müller-Miny, Louisa [Collaborator]; Musumeci, Olimpia [Collaborator]; S Nance, Christopher [Collaborator]; Natera-de Benito, Daniel [Collaborator]; Neel, Robert [Collaborator]; A Niizawa, Gabriela [Collaborator]; Noll, Lauren [Collaborator]; Ortega, Erik [Collaborator]; Pasnoor, Mamatha [Collaborator]; Pautot, Vivien [Collaborator]; Potulska-Chromik, Anna [Collaborator]; Pugliese, Alessia [Collaborator]; Questienne, Claire [Collaborator]; Ramos Lopes, Margarida [Collaborator]; Reyes-Leiva, David [Collaborator]; Riedl, Michaela [Collaborator]; Francisco Rugiero, Marcelo [Collaborator]; Salort-Campana, Emmanuelle [Collaborator]; Victor Sgobbi Souza, Paulo [Collaborator]; Sole, Guilhem [Collaborator]; Solera, Luca [Collaborator]; Souto Lopes, Suzara [Collaborator]; Specht, Sabine [Collaborator]; Statland, Jeffrey [Collaborator]; Swenson, Andrea [Collaborator]; Yew Tan, Chong [Collaborator]; Tizon, Sónia [Collaborator]; M Evan der Beek, N A [Collaborator]; A.van Kooten, Harmke [Collaborator]; Wencel, Marie [Collaborator]; Wenninger, Stephan [Collaborator]; Zagnoli, Fabien [Collaborator]