Nemzeti Kutatási Fejlesztési és Innovációs Hivatal(K135561)
Nemzeti Kutatási Fejlesztési és Innovációs Hivatal(KH125294)
Innovációs és Technológiai Minisztérium(ÚNKP-20-3-II)
High throughput, temporally controlled, reproducible quantitative behavioral assays
are important for understanding the neural mechanisms underlying behavior. Here, we
provide a step-by-step training protocol for a probabilistic Pavlovian conditioning
task, where two auditory cues predict probabilistic outcomes with different contingencies.
This protocol allows us to study the differential behavioral and neuronal correlates
of expected and surprising outcomes. It has been tested in combination with chronic
in vivo electrophysiological recordings and optogenetic manipulations in ChAT-Cre
and PV-Cre mouse lines. For complete details on the use and execution of this protocol,
please refer to Hegedüs et al. (2021).
