https://m2.mtmt.hu/ eng 2026-10-23 07:21 JournalArticle 32512363 VALIDATED true * Megosztott szerzőség 0 false 2026-10-21T23:20:26.907+0000 2026-03-08T23:38:36.625+0000 2021-11-27T07:01:35.792+0000 true 10013024 Molnár Gergő Attila /api/author/10013024 Author Gergő Attila Molnár (Belgyógyászat) true 10013024 2026-03-17T14:21:22.846+0000 2026-03-17T14:21:22.846+0000 2026-03-08T23:38:36.805+0000 true 10104369 Balázsné Balogh Ildikó /api/admin/10104369 Admin Ildikó Balázsné Balogh (NNGYK 4 admin) true true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Vokó, Zoltán true true /api/journal/10000627 REVIEWED CLINICAL MICROBIOLOGY AND INFECTION 1198-743X 1469-0691 true false 10000627 false 10000627 true 1198-743X 1469-0691 Journal FOREIGN 28 3 398 404 398 7 2022 Objectives The Hungarian vaccination campaign was conducted with five different vaccines during the third wave of the Covid-19 pandemic in 2021. This observational study (HUN-VE: Hungarian Vaccine Effectiveness) estimated vaccine effectiveness against SARS-CoV-2 infection and Covid-19 related mortality in 3.7 million vaccinated individuals. Methods Incidence rates of SARS-CoV-2 infection and Covid-19 related mortality were calculated using data from the National Public Health Center (NPHC) surveillance database. Estimated vaccine effectiveness was calculated as 1 – incidence rate ratio (IRR) ≥7 days after the second dose for each available vaccine vs. an unvaccinated control group using mixed effect negative binomial regression controlling for age, sex and calendar day. Results Between 22 January 2021 and 10 June 2021, 3,740,066 Hungarian individuals received two doses of the BNT162b2 (Pfizer-BioNTech), HB02 (Sinopharm), Gam-COVID-Vac (Sputnik-V), AZD1222 (AstraZeneca), or mRNA-1273 (Moderna) vaccines. Incidence rates of SARS-CoV2 infection and Covid-19 related death were 1.73–9.3/100,000 person-days and 0.04–0.65/100.000 person-days in the fully vaccinated population, respectively. Estimated adjusted effectiveness varied between 68.7% (95% CI 67.2–70.1%) and 88.7% (95% CI: 86.6–90.4%) against SARS-CoV-2 infection, and between 87.8% (95% CI: 86.1–89.5%) and 97.5% (95% CI: 95.6–98.6%) against Covid-19 related death, with 100% effectiveness in individuals aged 16–44 years for all vaccines. Conclusions Our observational study demonstrated the high or very high effectiveness of five different vaccines in the prevention SARS-CoV-2 infection and Covid-19 related death. true 2021 true true true false true false GOLD 2026-10-22 true https://doi.org/10.1016/j.cmi.2021.11.011 126 0 119 113 27 114 116 97 106 109 109 103 103 120 6 0 126 120 119 113 0 1 1 Folyóiratcikk Journal Article 24 114 Könyvrészlet Chapter in Book 25 2 Könyv Book 23 2 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 7 Alkotás Achievement 22 0 Kutatási adat Research data 33 1 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 55 52 55 52 2023 0 38 36 38 36 2024 0 20 19 20 19 2025 0 8 8 8 8 2026 0 5 5 5 5 D1 false 10011852,10013024,10016656,10058619,10028053 false false false 2022-02-25T07:04:55.974+0000 Bioinformatikai kutatócsoport (PTE / KCS); Digitális Egészségtudományi Intézet (SE / EKK); Egészségügyi Technológiaértékelő és Elemzési Kö... (SE / KSZE); II. sz. Belgyógyászati Klinika és Nephrológiai,... (PTE / ÁOK); Laboratóriumi Medicina Intézet (PTE / ÁOK); Nemzeti Népegészségügyi és Gyógyszerészeti Központ; Szentágothai János Kutatóközpont (PTE) 10 40 7 15 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 99507045 /api/authorship/99507045 Vokó, Zoltán [Vokó, Zoltán (A nem-fertőző bet...), author] Center for Health Technology Assessment (SU / KSZE) 1 0.067 true false false Author 10000181 /api/author/10000181 Zoltán Vokó (A nem-fertőző betegségek) Vokó Zoltán true 10000181 true Vokó Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507046 /api/authorship/99507046 Kiss, Zoltán* [Kiss, Zoltán (A főbb mortalitás...), author] Second Department of Medicine and Nephrology-Di... (UP / UPMS) 2 0.067 true false false Author 10077079 /api/author/10077079 Zoltán Kiss (A főbb mortalitásért felelős betegségek epidemiológiájának kutatása) Kiss Zoltán true true Kiss Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507047 /api/authorship/99507047 Surján, György [Surján, György (Orvosi informatika), author] Digitális Egészségtudományi Intézet (SU / DHS) 3 0.06666667 false false false Author 10028053 /api/author/10028053 György Surján (Orvosi informatika) Surján György true 10028053 true Surján György true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507048 /api/authorship/99507048 Surján, Orsolya 4 0.06666667 false false false Surján Orsolya true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507049 /api/authorship/99507049 Barcza, Zsófia 5 0.06666667 false false false Barcza Zsófia true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507050 /api/authorship/99507050 Pályi, Bernadett [Pályi, Bernadett (virológia), author] National Center for Public Health and Pharmacy 6 0.067 false false false Author 10082477 /api/author/10082477 Bernadett Pályi (virológia) Pályi Bernadett true true Pályi Bernadett true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507051 /api/authorship/99507051 Formanek-Balku, Eszter 7 0.06666667 false false false Formanek-Balku Eszter true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507052 /api/authorship/99507052 Molnár, Gergő Attila [Molnár, Gergő Attila (Belgyógyászat), author] Second Department of Medicine and Nephrology-Di... (UP / UPMS) 8 0.06666667 false false false Author 10013024 /api/author/10013024 Gergő Attila Molnár (Belgyógyászat) Molnár Gergő Attila true 10013024 true Molnár Gergő Attila true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507053 /api/authorship/99507053 Herczeg, Róbert [Herczeg, Róbert (Bioinformatika), author] Szentágothai Research Centre (UP); Bioinformatics research group (UP / RG) 9 0.06666667 false false false Author 10020885 /api/author/10020885 Róbert Herczeg (Bioinformatika) Herczeg Róbert true 10020885 true Herczeg Róbert true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507054 /api/authorship/99507054 Gyenesei, Attila [Gyenesei, Attila (Informatika, Bioi...), author] Szentágothai Research Centre (UP); Bioinformatics research group (UP / RG) 10 0.06666667 false false false Author 10058619 /api/author/10058619 Attila Gyenesei (Informatika, Bioinformatika) Gyenesei Attila true 10058619 true Gyenesei Attila true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507055 /api/authorship/99507055 Miseta, Attila [Miseta, Attila János (Laboratóriumi dia...), author] Department of Laboratory Medicine (UP / UPMS) 11 0.06666667 false false false Author 10011852 /api/author/10011852 Attila János Miseta (Laboratóriumi diagnosztika, molekuláris sejtbiológia, farmakogenetika) Miseta Attila János true 10011852 true Miseta Attila true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507056 /api/authorship/99507056 Kollár, Lajos 12 0.06666667 false false false Kollár Lajos true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507057 /api/authorship/99507057 Wittmann, István ✉ [Wittmann, István (Klinikai orvostud...), author] Second Department of Medicine and Nephrology-Di... (UP / UPMS) 13 0.067 false false true Author 10016656 /api/author/10016656 István Wittmann (Klinikai orvostudomány) Wittmann István true 10016656 true Wittmann István true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507058 /api/authorship/99507058 Müller, Cecília** 14 0.067 false true false Müller Cecília true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99507059 /api/authorship/99507059 Kásler, Miklós [Kásler, Miklós (Klinikai onkológia), author] 15 0.06666667 false true false Author 10024576 /api/author/10024576 Miklós Kásler (Klinikai onkológia) Kásler Miklós true 10024576 true Kásler Miklós true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 20234422 /api/publicationidentifier/20234422 DOI: 10.1016/j.cmi.2021.11.011 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1016/j.cmi.2021.11.011 https://doi.org/10.1016/j.cmi.2021.11.011 false true PublicationIdentifier 21502291 /api/publicationidentifier/21502291 WoS: 000821013600015 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000821013600015 https://www.webofscience.com/wos/woscc/full-record/000821013600015 true true PublicationIdentifier 20320150 /api/publicationidentifier/20320150 Scopus: 85121212464 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85121212464 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85121212464 false true PublicationIdentifier 20241842 /api/publicationidentifier/20241842 PubMed: 34838783 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 34838783 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34838783&dopt=Abstract true true Classification 12492 /api/classification/12492 SARS true true Classification 12348 /api/classification/12348 Prevention and treatment of infection by pathogens (e.g. vaccination, antibiotics, fungicide) true true SjrRating 11314209 /api/sjrrating/11314209 sjr:D1 (2022) Scopus - Infectious Diseases CLINICAL MICROBIOLOGY AND INFECTION 1198-743X 1469-0691 11 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2725 /api/classificationexternal/2725 Scopus - Infectious Diseases true 2725 true D1 DIRECT true true /api/publication/32512363 Vokó Zoltán et al. Nationwide effectiveness of five SARS-CoV-2 vaccines in Hungary - The HUN-VE study. (2022) CLINICAL MICROBIOLOGY AND INFECTION 1198-743X 1469-0691 28 3 398-404<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10000181"><a href="/gui2/?type=authors&mode=browse&sel=10000181" target="_blank">Vokó Zoltán (<span class="authorship-author-name">Vokó Zoltán</span> <span class="authorAux-mtmt"> A nem-fertőző betegségek</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Központi Szervezeti Egységek (beleértve az Egyéb Szervezeti Egységeket)">KSZE</span>/Center for Health Technology Assessment</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10077079"><a href="/gui2/?type=authors&mode=browse&sel=10077079" target="_blank">Kiss Zoltán^* (<span class="authorship-author-name">Kiss Zoltán</span> <span class="authorAux-mtmt"> A főbb mortalitásért felelős betegségek epidemi...</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Second Department of Medicine and Nephrology-Diabetes Centre</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10028053"><a href="/gui2/?type=authors&mode=browse&sel=10028053" target="_blank">Surján György (<span class="authorship-author-name">Surján György</span> <span class="authorAux-mtmt"> Orvosi informatika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Department of Hygienic Service">DHS</span>/Digitális Egészségtudományi Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Surján Orsolya </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barcza Zsófia </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10082477"><a href="/gui2/?type=authors&mode=browse&sel=10082477" target="_blank">Pályi Bernadett (<span class="authorship-author-name">Pályi Bernadett</span> <span class="authorAux-mtmt"> virológia</span>) </a> </span> <span class="author-affil">National Center for Public Health and Pharmacy</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Formanek-Balku Eszter </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013024"><a href="/gui2/?type=authors&mode=browse&sel=10013024" target="_blank">Molnár Gergő Attila (<span class="authorship-author-name">Molnár Gergő Attila</span> <span class="authorAux-mtmt"> Belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Second Department of Medicine and Nephrology-Diabetes Centre</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020885"><a href="/gui2/?type=authors&mode=browse&sel=10020885" target="_blank">Herczeg Róbert (<span class="authorship-author-name">Herczeg Róbert</span> <span class="authorAux-mtmt"> Bioinformatika</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/Szentágothai Research Centre; <span title="University of Pécs">UP</span>/<span title="Research Groups">RG</span>/Bioinformatics research group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10058619"><a href="/gui2/?type=authors&mode=browse&sel=10058619" target="_blank">Gyenesei Attila (<span class="authorship-author-name">Gyenesei Attila</span> <span class="authorAux-mtmt"> Informatika, Bioinformatika</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/Szentágothai Research Centre; <span title="University of Pécs">UP</span>/<span title="Research Groups">RG</span>/Bioinformatics research group</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011852"><a href="/gui2/?type=authors&mode=browse&sel=10011852" target="_blank">Miseta Attila (<span class="authorship-author-name">Miseta Attila János</span> <span class="authorAux-mtmt"> Laboratóriumi diagnosztika, molekuláris sejtbio...</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Department of Laboratory Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kollár Lajos </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016656"><a href="/gui2/?type=authors&mode=browse&sel=10016656" target="_blank">Wittmann István ✉ (<span class="authorship-author-name">Wittmann István</span> <span class="authorAux-mtmt"> Klinikai orvostudomány</span>) </a> </span> <span class="author-affil"><span title="University of Pécs">UP</span>/<span title="Medical School">UPMS</span>/Second Department of Medicine and Nephrology-Diabetes Centre</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Müller Cecília^** </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10024576"><a href="/gui2/?type=authors&mode=browse&sel=10024576" target="_blank">Kásler Miklós (<span class="authorship-author-name">Kásler Miklós</span> <span class="authorAux-mtmt"> Klinikai onkológia</span>) </a> </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32512363" target="_blank">Nationwide effectiveness of five SARS-CoV-2 vaccines in Hungary - The HUN-VE study</a></div> <div> <span class="journal-title">CLINICAL MICROBIOLOGY AND INFECTION</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1198-743X">1198-743X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1469-0691">1469-0691</a>)</span>: <span class="journal-volume">28</span> <span class="journal-issue">3</span> <span class="page"> pp 398-404 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1016/j.cmi.2021.11.011" target="_blank" href="https://doi.org/10.1016/j.cmi.2021.11.011"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000821013600015" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000821013600015"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85121212464" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85121212464"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34838783" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34838783&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Infectious Diseases&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Microbiology (medical)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 126</span> | Independent citation: 120 | Self citation: 6 | Unknown citation: 0 | Number of citations in WoS: 97 | Number of citations in Scopus:&nbsp;106 | WoS/Scopus assigned:&nbsp;109 | Number of citations with DOI:&nbsp;116 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32512363&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32512363</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="lastModified">Last Modified: 2026.03.09. 00:38 Ildikó Balázsné Balogh (NNGYK 4 admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: * Megosztott szerzőség</pre> </div></div>