Objectives: The aim of this prospective case series was to evaluate single-piece zirconia
implants restored with lithium disilicate CAD/CAM crowns through a long-term follow-up.
Methods: In this trial, 20 one-piece zirconia implants were placed in 20 patients.
Implants were restored (i) immediately with lithium disilicate CAD/CAM provisionals,
and (ii) permanently four months after surgery. Patients were followed for 11 years.
Clinical parameters and radiological measurements of the zirconia implants were assessed.
For the statistical analysis, paired t-test was applied. Results: Four implants were
counted as implant failure due to the loss of implant stability, resulting in a Kaplan–Meier
survival rate of 80% up to 11 years. The mean bleeding on probing values were 19.1%
(SD ± 13.1) and 18.2% (SD ± 17.6) 96 and 11 years after implant placement, respectively.
The plaque index revealed a significant decrease over time (p < 0.001) with a value
between 25.9% (SD ± 5.7) and 12.6% (SD ± 10.0) at baseline and 11-years follow-up
respectively. The marginal bone level revealed a significant decrease 4, 8, and 11
years after implant insertion (p = 0.001, p = 0.019, and p = 0.027, respectively).
Conclusions: Immediately loaded zirconia single-piece implants showed a suitable success
rate in clinical and radiographic outcomes.
