https://m2.mtmt.hu/ eng 2026-05-01 15:38 JournalArticle 32505562 VALIDATED true Export Date: 11 February 2025 0 false 2026-04-17T10:22:29.678+0000 2024-12-06T18:00:00.377+0000 2021-11-23T10:48:17.135+0000 true 10074555 Molnár-Taga Márta /api/admin/10074555 Admin true 2026-02-18T14:48:44.005+0000 2024-12-06T18:00:01.187+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Molnár, A.Á. The aging venous system: from varicosities to vascular cognitive impairment true true /api/journal/10071822 REVIEWED true false 10071822 false 10071822 true 2509-2715 2509-2723 Journal FOREIGN 43 6 2761 2784 2761 24 2021 Aging-induced pathological alterations of the circulatory system play a critical role in morbidity and mortality of older adults. While the importance of cellular and molecular mechanisms of arterial aging for increased cardiovascular risk in older adults is increasingly appreciated, aging processes of veins are much less studied and understood than those of arteries. In this review, age-related cellular and morphological alterations in the venous system are presented. Similarities and dissimilarities between arterial and venous aging are highlighted, and shared molecular mechanisms of arterial and venous aging are considered. The pathogenesis of venous diseases affecting older adults, including varicose veins, chronic venous insufficiency, and deep vein thrombosis, is discussed, and the potential contribution of venous pathologies to the onset of vascular cognitive impairment and neurodegenerative diseases is emphasized. It is our hope that a greater appreciation of the cellular and molecular processes of vascular aging will stimulate further investigation into strategies aimed at preventing or retarding age-related venous pathologies. © 2021, The Author(s). Funding 2012258 /api/funding/2012258 false true true 2021 true true true false true false NONE 2026-04-17 false 66 0 66 63 2 65 64 61 54 66 66 63 63 63 3 0 66 63 66 63 0 37 37 Folyóiratcikk Journal Article 24 63 Könyvrészlet Chapter in Book 25 3 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 7 7 7 7 2023 0 18 18 18 18 2024 0 15 14 15 14 2025 0 21 19 21 19 2026 0 5 5 5 5 D1 false 10015399,10010428 false false false 2021-11-25T11:12:36.074+0000 Kardiológia Központ - Kardiológiai Tanszék (SE / AOK / K); Morfológiai és Fiziológiai Tanszék (SE / ETK2007); Népegészségtani Intézet (SE / AOK / I); Sportorvostan Tanszék (SE / AOK / K); Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K); Élettani Intézet (SE / AOK / I) 7 72 6 9 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 99472521 /api/authorship/99472521 1 0.111 true false true Author 10015399 /api/author/10015399 Molnár Andrea Ágnes true 10015399 true Molnár A.Á. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472522 /api/authorship/99472522 2 0.111 false false false Author 10023262 /api/author/10023262 Nádasy György László true 10023262 true Nádasy G.L. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472523 /api/authorship/99472523 3 0.111 false false false Author 10010428 /api/author/10010428 Bednárikné Dörnyei Gabriella true 10010428 true Dörnyei G. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472524 /api/authorship/99472524 4 0.11111111 false false false Author 10057225 /api/author/10057225 Patai Bernadett Bettina true 10057225 true Patai B.B. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472525 /api/authorship/99472525 5 0.11111111 false false false Delfavero J. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472526 /api/authorship/99472526 6 0.111 false false false Author 10044572 /api/author/10044572 Fülöp Gábor Áron true 10044572 true Fülöp G.Á. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472527 /api/authorship/99472527 7 0.11111111 false false false Kirkpatrick A.C. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472528 /api/authorship/99472528 8 0.111 false false false Author 10043602 /api/author/10043602 Ungvári Zoltán István true 10043602 true Ungvári Z. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 99472529 /api/authorship/99472529 9 0.111 false true false Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely B. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 20217578 /api/publicationidentifier/20217578 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1007/s11357-021-00475-2 https://doi.org/10.1007/s11357-021-00475-2 false true PublicationIdentifier 20217579 /api/publicationidentifier/20217579 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false 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/api/reference/25263393 279 false true Reference 25263304 /api/reference/25263304 280 false true /api/publication/32505562 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10015399"><a href="/gui2/?type=authors&mode=browse&sel=10015399" target="_blank">Molnár A.Á. ✉ (<span class="authorship-author-name">Molnár Andrea Ágnes</span> <span class="authorAux-mtmt"> kardiológia, belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023262"><a href="/gui2/?type=authors&mode=browse&sel=10023262" target="_blank">Nádasy G.L. (<span class="authorship-author-name">Nádasy György László</span> <span class="authorAux-mtmt"> Keringésélettan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Physiology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010428"><a href="/gui2/?type=authors&mode=browse&sel=10010428" target="_blank">Dörnyei G. (<span class="authorship-author-name">Bednárikné Dörnyei Gabriella</span> <span class="authorAux-mtmt"> Érfiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Health Sciences">FHS</span>/Department of Morphology and Physiology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10057225"><a href="/gui2/?type=authors&mode=browse&sel=10057225" target="_blank">Patai B.B. (<span class="authorship-author-name">Patai Bernadett Bettina</span> <span class="authorAux-mtmt"> élettan</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Delfavero J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044572"><a href="/gui2/?type=authors&mode=browse&sel=10044572" target="_blank">Fülöp G.Á. (<span class="authorship-author-name">Fülöp Gábor Áron</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kirkpatrick A.C. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10043602"><a href="/gui2/?type=authors&mode=browse&sel=10043602" target="_blank">Ungvári Z. (<span class="authorship-author-name">Ungvári Zoltán István</span> <span class="authorAux-mtmt"> Orvostudomány, megelőző orvostan, népegészségta...</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Department of Public Health</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely B. (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Cardiovascular Center; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Department of Cardiology – Heart and Vascular Center; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Cardiovascular Center">Cardiovascular Center</span>/Faculty of Sports Medicine</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32505562" target="_blank">The aging venous system: from varicosities to vascular cognitive impairment</a></div> <div> <span class="journal-title">GEROSCIENCE: OFFICIAL JOURNAL OF THE AMERICAN AGING ASSOCIATION (AGE)</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2509-2715">2509-2715</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2509-2723">2509-2723</a>)</span>: <span class="journal-volume">43</span> <span class="journal-issue">6</span> <span class="page"> pp 2761-2784 </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1007/s11357-021-00475-2" target="_blank" href="https://doi.org/10.1007/s11357-021-00475-2"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000717390100002" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000717390100002"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85118869467" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85118869467"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34762274" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34762274&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Aging&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Complementary and Alternative Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Geriatrics and Gerontology&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Veterinary (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Cardiology and Cardiovascular Medicine&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 66</span> | Independent citation: 63 | Self citation: 3 | Unknown citation: 0 | Number of citations in WoS: 61 | Number of citations in Scopus:&nbsp;54 | WoS/Scopus assigned:&nbsp;66 | Number of citations with DOI:&nbsp;64 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32505562&sort=publishedYear,desc&sort=title"> Number of cited publications: 37 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32505562</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Survey paper ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="funder"> (Open access funding provided by Semmelweis University) </div> <div class="lastModified">Last Modified: 2024.12.06. 19:00 Róbert Milánkovics (PTE ÁOK admin 4) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Export Date: 11 February 2025</pre> </div></div>