https://m2.mtmt.hu/ eng 2026-09-22 05:43 JournalArticle 3248294 VALIDATED true Neural Circuits Laboratory, Friedrich Miescher Institute, Basel, Switzerland Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary Faculty of Information Technology, Pázmány Péter Catholic University, Budapest, Hungary Department of Ophthalmology, University of Basel, Basel, Switzerland Cited By :76 Export Date: 10 October 2024 CODEN: NANEF Correspondence Address: Roska, B.; Neural Circuits Laboratory, Switzerland; email: botond.roska@fmi.ch Chemicals/CAS: Cytoskeletal Proteins; Diphtheria Toxin; FRMD7 protein, mouse Funding details: Horizon 2020 Framework Programme, H2020, 669157, 682426, 694829 Funding details: Seventh Framework Programme, FP7, 267351 Funding details: European Research Council, ERC Funding details: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, SNF, CRSII3-141801 Funding details: Eidgenössische Technische Hochschule Zürich, ETH Funding text 1: The ETH Zurich group, M.F. and A.H. acknowledge funding through the European Research Council Advanced Grant NeuroCMOS, contract number AdG 267351, and through the Swiss National Science Foundation Sinergia Project CRSII3-141801. 0 2018-10-02T08:54:25.000+0000 false 3248294 2026-08-30T06:18:02.816+0000 2022-12-06T13:01:15.524+0000 2017-07-12T13:48:40.000+0000 true 10012926 Rózsa J. Balázs /api/author/10012926 Author true 10012926 2025-03-22T18:51:06.976+0000 2025-03-22T18:51:06.976+0000 2022-12-06T13:01:15.793+0000 true 10069305 Kondor Zóra /api/admin/10069305 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Hillier, D Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex. true true /api/journal/19517 REVIEWED true false 19517 false 19517 true 1097-6256 1546-1726 Journal FOREIGN 20 7 960 968 960 9 2017 How neuronal computations in the sensory periphery contribute to computations in the cortex is not well understood. We examined this question in the context of visual-motion processing in the retina and primary visual cortex (V1) of mice. We disrupted retinal direction selectivity, either exclusively along the horizontal axis using FRMD7 mutants or along all directions by ablating starburst amacrine cells, and monitored neuronal activity in layer 2/3 of V1 during stimulation with visual motion. In control mice, we found an over-representation of cortical cells preferring posterior visual motion, the dominant motion direction an animal experiences when it moves forward. In mice with disrupted retinal direction selectivity, the over-representation of posterior-motion-preferring cortical cells disappeared, and their responses at higher stimulus speeds were reduced. This work reveals the existence of two functionally distinct, sensory-periphery-dependent and -independent computations of visual motion in the cortex. true true 2017 767153 true true true false true false PAY 2026-08-30 false 97 1 97 86 5 97 97 89 94 97 97 86 86 86 11 0 97 86 97 86 0 4 4 Folyóiratcikk Journal Article 24 87 Könyvrészlet Chapter in Book 25 10 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2017 0 5 4 5 4 2018 0 17 14 17 14 2019 0 12 10 12 10 2020 0 15 13 15 13 2021 0 4 4 4 4 2022 0 12 11 12 11 2023 0 7 7 7 7 2024 0 9 8 9 8 2025 0 11 10 11 10 2026 0 5 5 5 5 D1 false 10046111 false false false 2017-11-07T10:29:43.000+0000 2017-07-12T13:53:41.000+0000 MTA-PPKE ITK-NAP B Kétfoton méréstechnikai kuta... (PPKE / ITK); Neuronhálózat és Dendritikus Aktivitás Kutatócs... 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Balázs true 10012926 true Rozsa B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26605732 true PersonAuthorship 9192059 /api/authorship/9192059 11 0.091 false true true Author 10079728 /api/author/10079728 Roska Botond true true Roska B true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 26605731 true PublicationIdentifier 1213926 /api/publicationidentifier/1213926 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true PAY false IDENTICAL 10.1038/nn.4566 https://doi.org/10.1038/nn.4566 false 1612047 true PublicationIdentifier 14640628 /api/publicationidentifier/14640628 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000404115100012 https://www.webofscience.com/wos/woscc/full-record/000404115100012 false true PublicationIdentifier 1213925 /api/publicationidentifier/1213925 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 85021436779 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85021436779 false 1662469 true PublicationIdentifier 1213927 /api/publicationidentifier/1213927 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 28530661 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28530661&dopt=Abstract false 1612048 true Classification 12125 /api/classification/12125 true true SjrRating 10717815 /api/sjrrating/10717815 2 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2801 /api/classificationexternal/2801 true 2801 true D1 DIRECT true true /api/publication/3248294 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10046111"><a href="/gui2/?type=authors&mode=browse&sel=10046111" target="_blank">Hillier D (<span class="authorship-author-name">Hillier Dániel</span> <span class="authorAux-mtmt"> Idegtudomány, látórendszer, vizuális számítások...</span>) </a> </span> <span class="author-affil"><span title="MTA Research Centre for Natural Sciences">MTA TTK</span>/<span title="Institute of Cognitive Neuroscience and Psychology">KPI</span>/Összehasonlító Pszichofiziológiai Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Fiscella M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Drinnenberg A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Trenholm S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Rompani SB </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Raics Z </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="191"><a href="/gui2/?type=authors&mode=browse&sel=191" target="_blank">Katona G (<span class="authorship-author-name">Katona Gergely</span> <span class="authorAux-mtmt"> Farmakológia</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/<span title="Információs Technológiai és Bionikai Kar">ITK</span>/MTA-PPKE ITK-NAP B Two-photon measurement technology research group; <span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Juettner J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hierlemann A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012926"><a href="/gui2/?type=authors&mode=browse&sel=10012926" target="_blank">Rozsa B (<span class="authorship-author-name">Rózsa J. Balázs</span> <span class="authorAux-mtmt"> Idegtudomány, fizika</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Pharmacology">DP</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10079728"><a href="/gui2/?type=authors&mode=browse&sel=10079728" target="_blank">Roska B ✉ (<span class="authorship-author-name">Roska Botond</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3248294" target="_blank">Causal evidence for retina-dependent and -independent visual motion computations in mouse cortex.</a></div> <div> <span class="journal-title">NATURE NEUROSCIENCE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1097-6256">1097-6256</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1546-1726">1546-1726</a>)</span>: <span class="journal-volume">20</span> <span class="journal-issue">7</span> <span class="page"> pp 960-968 </span> <span class="year">(2017)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Pay "> <a style="color:blue" title="10.1038/nn.4566" target="_blank" href="https://doi.org/10.1038/nn.4566"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000404115100012" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000404115100012"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85021436779" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85021436779"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="28530661" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28530661&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 97</span> | Independent citation: 86 | Self citation: 11 | Unknown citation: 0 | Number of citations in WoS: 89 | Number of citations in Scopus:&nbsp;94 | WoS/Scopus assigned:&nbsp;97 | Number of citations with DOI:&nbsp;97 (Not published:&nbsp;1) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3248294&sort=publishedYear,desc&sort=title"> Number of cited publications: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 3248294</span> | <span class="status-data status-VALIDATED"> Validated </span> <span class="oldId">Old id: 3248294</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Last Modified: 2022.12.06. 14:01 Zóra Kondor (SE_KK_Admin5_KZ, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Neural Circuits Laboratory, Friedrich Miescher Institute, Basel, Switzerland Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary Faculty of Information ...</pre> </div></div>