https://m2.mtmt.hu/ eng 2026-06-24 00:31 JournalArticle 32467836 VALIDATED true Cited By :6 Export Date: 10 July 2024 Correspondence Address: Langenbucher, A.; Department of Experimental Ophthalmology, Germany; email: achim.langenbucher@uks.eu Tradenames: IOLMaster, Carl Zeiss Microscopy, Germany Manufacturers: Carl Zeiss Microscopy, Germany 0 false 2026-05-21T08:10:06.853+0000 2023-04-10T12:02:15.702+0000 2021-10-26T09:22:52.515+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Márta Molnár-Taga (SE 4-es admin) true 10062250 2024-07-10T12:04:52.957+0000 2023-04-10T12:02:15.956+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Márta Molnár-Taga (SE 4-es admin) true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Langenbucher, A. true true /api/journal/10009508 REVIEWED ACTA OPHTHALMOLOGICA 1755-375X 1755-3768 true false 10009508 false 10009508 true 1755-375X 1755-3768 Journal FOREIGN 100 5 e1080 e1087 e1080 2022 Background: The corneal back surface is known to add some astigmatism against-the-rule, which has to be considered in cataract surgery with toric lens implantation. The purpose of this study was to set up a deep learning algorithm which predicts the total corneal power from keratometry and biometric measures. Methods: Based on a large data set of measurements with the IOLMaster 700 from two clinical centres, data from N = 21 108 eyes were included, each record containing valid data for keratometry K, total keratometry TK, axial length AL, central corneal thickness CCT, anterior chamber depth ACD, lens thickness LT and horizontal corneal diameter W2W from an individual eye. After a vector decomposition of K and TK into equivalent power (.EQ) and projections of astigmatism to the 0°/90° (.AST0°) and 45°/135° (.AST45°) axis, a multi-output feedforward shallow neural network was derived to predict TK from K, AL, CCT, ACD, LT, W2W and patient age. Results: After some trial and error, the neural network having a Levenberg–Marquardt training function and three hidden layers (10/8/5 neurons) performed best and showed a fast convergence. The data set was split into training data (70%), validation data (15%) and test data (15%). The prediction error (predicted corneal power CPpred minus TK) of the network trained with the training and cross-validated with test data showed systematically narrower distributions for CPEQ-TKEQ, CPAST0°-TKAST0° and CPAST45°-TKAST45° compared with KEQ-TKEQ, KAST0°-TKAST0° and KAST45°-TKAST45°. There was no systematic offset in the components between CPpred and TK. Conclusion: Unlike any fixed correction term, which can compensate only for a static intercept of the astigmatic components TKEQ, TKAST0° and TKAST45° compared with KEQ, KAST0° and KAST45°, our trained neural network was able to reduce the variance in the prediction error significantly. This neural network could be used to account for the corneal back surface astigmatism for biometers where the corneal back surface measurement or total keratometry is not available. © 2021 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation true true 2021 true true true false true false NONE 2026-05-21 false 12 0 12 4 7 11 12 11 12 12 12 4 4 4 8 0 12 4 12 4 0 1 1 Folyóiratcikk Journal Article 24 10 Könyvrészlet Chapter in Book 25 2 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2023 0 2 0 2 0 2024 0 6 2 6 2 2025 0 2 1 2 1 2026 0 2 1 2 1 Q1 false false false false 2022-01-24T10:24:50.404+0000 Szemészeti Klinika (SE / AOK / K) 2 5 1 6 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 99195965 /api/authorship/99195965 Langenbucher, A. ✉ [Langenbucher, Achim (Ophthalmology, op...), author] 1 0.167 true false true Author 10072292 /api/author/10072292 Achim Langenbucher (Ophthalmology, ophthalmic optics) Langenbucher Achim true true Langenbucher A. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99195966 /api/authorship/99195966 Cayless, A. 2 0.16666667 false false false Cayless A. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99195967 /api/authorship/99195967 Szentmáry, N. [Szentmáry, Nóra (Szemészet), author] Department of Ophthalmology (SU / FM / C) 3 0.167 false false false Author 10000048 /api/author/10000048 Nóra Szentmáry (Szemészet) Szentmáry Nóra true 10000048 true Szentmáry N. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99195968 /api/authorship/99195968 Weisensee, J. 4 0.16666667 false false false Weisensee J. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99195969 /api/authorship/99195969 Wendelstein, J. 5 0.16666667 false false false Wendelstein J. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 99195970 /api/authorship/99195970 Hoffmann, P. 6 0.16666667 false true false Hoffmann P. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 20123056 /api/publicationidentifier/20123056 DOI: 10.1111/aos.15040 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1111/aos.15040 https://doi.org/10.1111/aos.15040 false true PublicationIdentifier 20129171 /api/publicationidentifier/20129171 WoS: 000708256100001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000708256100001 https://www.webofscience.com/wos/woscc/full-record/000708256100001 true true PublicationIdentifier 20123055 /api/publicationidentifier/20123055 Scopus: 85117229380 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85117229380 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85117229380 false true PublicationIdentifier 20129166 /api/publicationidentifier/20129166 PubMed: 34664393 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 34664393 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34664393&dopt=Abstract true true Keyword 6369 /api/keyword/6369 Neural network true 6369 true Keyword 16626 /api/keyword/16626 Biometry true 16626 true Keyword 1427322 /api/keyword/1427322 Deep learning true 1427322 true Keyword 1447582 /api/keyword/1447582 posterior corneal astigmatism true 1447582 true Keyword 2529894 /api/keyword/2529894 corneal back surface true true Keyword 2529895 /api/keyword/2529895 feedforward multi-output network true true SjrRating 11309375 /api/sjrrating/11309375 sjr:Q1 (2022) Scopus - Medicine (miscellaneous) ACTA OPHTHALMOLOGICA 1755-375X 1755-3768 387 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 Scopus - Medicine (miscellaneous) true 2701 true Q1 DIRECT true true Reference 24642456 /api/reference/24642456 1. 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(2022) ACTA OPHTHALMOLOGICA 1755-375X 1755-3768 100 5 e1080-e1087<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10072292"><a href="/gui2/?type=authors&mode=browse&sel=10072292" target="_blank">Langenbucher A. ✉ (<span class="authorship-author-name">Langenbucher Achim</span> <span class="authorAux-mtmt"> Ophthalmology, ophthalmic optics</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Cayless A. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000048"><a href="/gui2/?type=authors&mode=browse&sel=10000048" target="_blank">Szentmáry N. (<span class="authorship-author-name">Szentmáry Nóra</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Weisensee J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Wendelstein J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hoffmann P. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32467836" target="_blank">Prediction of total corneal power from measured anterior corneal power on the IOLMaster 700 using a feedforward shallow neural network</a></div> <div> <span class="journal-title">ACTA OPHTHALMOLOGICA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1755-375X">1755-375X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1755-3768">1755-3768</a>)</span>: <span class="journal-volume">100</span> <span class="journal-issue">5</span> <span class="page"> pp e1080-e1087 </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1111/aos.15040" target="_blank" href="https://doi.org/10.1111/aos.15040"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000708256100001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000708256100001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85117229380" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85117229380"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34664393" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34664393&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Ophthalmology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 12</span> | Independent citation: 4 | Self citation: 8 | Unknown citation: 0 | Number of citations in WoS: 11 | Number of citations in Scopus:&nbsp;12 | WoS/Scopus assigned:&nbsp;12 | Number of citations with DOI:&nbsp;12 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32467836&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32467836</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Last Modified: 2023.04.10. 14:02 Márta Molnár-Taga (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Cited By :6 Export Date: 10 July 2024 Correspondence Address: Langenbucher, A.; Department of Experimental Ophthalmology, Germany; email: achim.langenbucher@uks.eu Tradenames: IOLMaster, Carl Zeiss Microscopy, Germany Manufacturers: Carl Zeiss Microscopy, Germany</pre> </div></div>