https://m2.mtmt.hu/ eng 2026-09-21 15:34 JournalArticle 32397103 VALIDATED true 0 false 2026-09-13T19:26:35.448+0000 2026-05-29T12:53:30.708+0000 2021-10-15T08:01:50.697+0000 true 10065463 Turek Márta /api/admin/10065463 Admin true 2026-09-03T09:05:07.498+0000 2026-09-03T09:05:07.498+0000 2026-05-29T12:53:30.959+0000 true 10014559 Bolgár Andrea /api/admin/10014559 Admin true 10014559 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Fedor, Flóra Zsófia Soft, Thiol‐ene/Acrylate‐Based Electrode Array for Long‐Term Recording of Intracranial EEG Signals with Improved Biocompatibility in Mice true true /api/journal/10061718 REVIEWED true false 10061718 false 10061718 true 2365-709X 2365-709X Journal FOREIGN 7 5 2100942 2100942 10 2022 Thiol‐ene/acrylate, a softening polymer material, rapidly gained attention during the past few years as a substrate of intracortical probes, as soft polymers can mitigate foreign body response by reducing mechanical mismatch between the neural implant and the surrounding brain tissue. This paper presents a comprehensive analysis of a thiol‐ene/acrylate based microECoG (micro – electrocorticography, μECoG) device with 31 sputtered iridium oxide electrodes. Long‐term electrochemical measurements provide firm evidence on the reliability of the novel layer structure and the related packaging method. In vivo impedance measurements indicated stable electrode yield (over 75%), without apparent signs of delamination or material degradation over 75 days. Awake recordings of theta oscillations with signal‐to‐noise ratio between 1.04 and 5.74 over this extended period also confirmed the applicability of the device. Chronic immune response characterized by Glial Fibrillary Acidic Protein staining of astrocytes and fluorescent Nissl (NeuroTrace) staining of neurons revealed only modest foreign body reaction after 80 days of implantation. The study presents novel data that confirms the feasibility of softening polymer‐based μECoG devices as chronically implantable neural interfaces. 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(HRN KOKI); Roska Tamás Műszaki és Természettudományi Dokto... 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Balázs true 10012926 true Rózsa Balázs true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 98648153 /api/authorship/98648153 10 0.1 false true true Author 10023418 /api/author/10023418 Fekete Zoltán true 10023418 true Fekete Zoltán true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 19897237 /api/publicationidentifier/19897237 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1002/admt.202100942 https://doi.org/10.1002/admt.202100942 false true PublicationIdentifier 20129196 /api/publicationidentifier/20129196 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000705120500001 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src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080381"><a href="/gui2/?type=authors&mode=browse&sel=10080381" target="_blank">Fedor Flóra Zsófia (<span class="authorship-author-name">Fedor Flóra Zsófia</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Centre for Energy Research">CER</span>/Institute of Technical Physics and Materials Science; <span title="Centre for Energy Research">CER</span>/<span title="Institute of Technical Physics and Materials Science">MFA</span>/Mikrorendszerek Laboratórium; <span title="University of Pannonia">UP</span>/Faculty of Engineering; <span title="Pázmány Péter Catholic University">PPCU</span>/Információs Technológiai és Bionikai Kar; <span title="Institute of Experimental Medicine">IEM</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10051355"><a href="/gui2/?type=authors&mode=browse&sel=10051355" target="_blank">Madarász Miklós<sup>*</sup> (<span class="authorship-author-name">Madarász Miklós</span> <span class="authorAux-mtmt"> Neurobiológia</span>) </a> </span> <span class="author-affil"><span title="Institute of Experimental Medicine">IEM</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport; <span title="Semmelweis University">SU</span>/School of PhD Studies</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10058750"><a href="/gui2/?type=authors&mode=browse&sel=10058750" target="_blank">Zátonyi Anita<sup>*</sup> (<span class="authorship-author-name">Zátonyi Anita</span> <span class="authorAux-mtmt"> Mikrotechnológia</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/Információs Technológiai és Bionikai Kar</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065203"><a href="/gui2/?type=authors&mode=browse&sel=10065203" target="_blank">Szabó Ágnes (<span class="authorship-author-name">Szabó Ágnes</span> <span class="authorAux-mtmt"> neuroMEMS</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/<span title="Információs Technológiai és Bionikai Kar">ITK</span>/Roska Tamás Műszaki és Természettudományi Doktori Iskola</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10063614"><a href="/gui2/?type=authors&mode=browse&sel=10063614" target="_blank">Lőrincz Tibor (<span class="authorship-author-name">Lőrincz Tibor</span> <span class="authorAux-mtmt"> elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Institute of Experimental Medicine">IEM</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Danda Vindhya </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Spurgin Lisa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Manz Connie </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012926"><a href="/gui2/?type=authors&mode=browse&sel=10012926" target="_blank">Rózsa Balázs (<span class="authorship-author-name">Rózsa J. Balázs</span> <span class="authorAux-mtmt"> Idegtudomány, fizika</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/Információs Technológiai és Bionikai Kar; <span title="Institute of Experimental Medicine">IEM</span>/Neuronhálózat és Dendritikus Aktivitás Kutatócsoport; Institute of Experimental Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10023418"><a href="/gui2/?type=authors&mode=browse&sel=10023418" target="_blank">Fekete Zoltán ✉ (<span class="authorship-author-name">Fekete Zoltán</span> <span class="authorAux-mtmt"> neuroMEMS</span>) </a> </span> <span class="author-affil"><span title="Pázmány Péter Catholic University">PPCU</span>/Információs Technológiai és Bionikai Kar</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32397103" target="_blank">Soft, Thiol‐ene/Acrylate‐Based Electrode Array for Long‐Term Recording of Intracranial EEG Signals with Improved Biocompatibility in Mice</a></div> <div> <span class="journal-title">ADVANCED MATERIALS TECHNOLOGIES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2365-709X">2365-709X</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2365-709X">2365-709X</a>)</span>: <span class="journal-volume">7</span> <span class="journal-issue">5</span> <span class="page"> Paper 2100942. 10 p. </span> <span class="year">(2022)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1002/admt.202100942" target="_blank" href="https://doi.org/10.1002/admt.202100942"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000705120500001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000705120500001"> WoS </a> </span> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="135752" target="_blank" href="https://real.mtak.hu/135752"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85116843158" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85116843158"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="16316198918321238108" target="_blank" href="http://scholar.Google.com/scholar?hl=en&lr=&cluster=16316198918321238108"> Google scholar </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Industrial and Manufacturing Engineering&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Materials Science (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Mechanics of Materials&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 23</span> | Independent citation: 18 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 22 | Number of citations in Scopus:&nbsp;23 | WoS/Scopus assigned:&nbsp;23 | Number of citations with DOI:&nbsp;23 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32397103&sort=publishedYear,desc&sort=title"> Number of cited publications: 9 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32397103</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (FK 134403) Funder: NRDIO, (TKP2020-NKA-11), Hungarian National Brain Research Program(2017-1.2.1-NKP-2017-00002), European Research Council (ERC)(682426,), (2018-1.1.2-KFI-2018-00097), (VKE-2018-00032), European Research Council(712821-NEURAM), (ÚNKP-20-3), (ÚNKP-20-3-II-PPKE-28) </div> <div class="lastModified">Last Modified: 2026.05.29. 14:53 Andrea Bolgár (MFA admin 4) </div> </div></div>