https://m2.mtmt.hu/ eng 2026-06-27 18:45 JournalArticle 32367392 VALIDATED true Semmelweis Egyetem, Általános Orvostudományi Kar, Szemészeti Klinika, Budapest, Hungary Magyar Honvédség Egészségügyi Központ, Szemészeti Osztály, Budapest, Hungary Markusovszky Egyetemi Oktatókórház, Szemészeti Osztály, Szombathely, Hungary Experimental Ophthalmology, Saarland University, Saar, Homburg, Germany Semmelweis Egyetem, Általános Orvostudományi Kar, III. Belgyógyászati és Hematológiai Klinika, Budapest, Hungary Dél-pesti Centrum Kórház, Országos Hematológiai és Infektológiai Intézet, Hematológiai és Őssejt-Transzplantációs Osztály, Budapest, Hungary Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Saar, Homburg, Germany Mária u. 39, Budapest, 1085, Hungary Export Date: 05 July 2025; Cited By: 0; CODEN: ORHEA 0 false 2026-05-21T06:33:29.863+0000 2023-02-20T17:29:58.046+0000 2021-10-13T09:42:44.884+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin true 2025-07-05T14:09:52.799+0000 2022-05-23T13:46:49.897+0000 true 10062062 Gere Tamásné /api/admin/10062062 Admin true 10062062 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Kormanyos, Kitti A monoklonális gammopathia szemészeti jelei és szövődményei 42 beteg 84 szemének vizsgálata Ocular signs and comorbidities in monoclonal gammopathy Analysis of 84 eyes of 42 subjects true true /api/journal/1035675 REVIEWED true true 1035675 false 1035675 true 0030-6002 1788-6120 Journal HUNGARIAN 162 38 1533 1540 1533 8 2021 Objective: To examine ocular signs and ocular comorbidities in monoclonal gammopathy. Patients and methods: We analyzed patients from two large referral hematology centers in Budapest, who were diagnosed and/or treated with monoclonal gammopathy between 1997 and 2020 (84 eyes of 42 patients, 42.86% male, mean age 63.83 +/- 10.76 years). Before the ophthalmic examination, the subjects filled in the Ocular Surface Disease Index (OSDI) questionnaire. Ophthalmic examination included visual acuity test and slit-lamp examination following dilation of the pupil. Results: OSDI scores were significantly higher in subjects with monoclonal gammopathy than in controls (p = 0.002). Among gammopathy subjects, we observed potential corneal immunoglobulin deposition in 5 eyes of 3 patients (5.95%). In gammopathy subjects, there was dry eye disease (66.67%), cataract (55.95%), Meibomian gland dysfunction (20.24%), posterior cortical cataract (19.05%), corneal scars and degenerations (17.86%), chronic blepharitis (14.29%), absence of ocular complaint (11.90%), macular or retinal drusen (9.52%), corneal immunoglobulin deposition (5.95%), epiretinal membrane (5.95%), previous cataract surgery (5.95%), glaucoma (4.76%), Fuchs dystrophy (2.38%), peripheral retinal degeneration (2.38%), chorioideal naevus (2.38%), diabetic retinopathy (1.19%), central retinal artery occlusion (1.19%), central retinal vein branch occlusion (1.19%) and amblyopia (1.19%). The proportion of dry eye disease (p = 0.002), posterior cortical cataract (p = 0.001), cataract (p<0.00001), and corneal scars and degenerations (p = 0.01) were significantly higher in gammopathy subjects than in controls. Conclusion: Dry eye disease and cataracts are the most common ocular comorbidities in patients with monoclonal gammopathy. Therefore, due to the potential ocular signs and comorbidities of monoclonal gammopathy, we suggest a regular, yearly ophthalmic checkup of these patients to improve their quality of life. true true 2021 false false true false true false GOLD 2026-05-21 true https://doi.org/10.1556/650.2021.32228 1 0 1 1 1 0 1 0 0 0 0 0 0 1 0 0 1 1 1 1 0 3 3 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2025 0 1 1 1 1 Q4 A false false false false 2021-10-12T09:49:45.848+0000 III. 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Belgyógyászati Klinika (SE / AOK / K); Szemészeti Klinika (SE / AOK / K); Vas Megyei Markusovszky Kórház Nonprofit Zrt. 12 19 3 13 0 true Language 10001 /api/language/10001 Magyar Hungarian true 1 true PersonAuthorship 98466583 /api/authorship/98466583 1 0.077 true false true Author 10080625 /api/author/10080625 Kormányos Kitti true true Kormanyos Kitti true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 98466584 /api/authorship/98466584 2 0.077 false false false Author 10070765 /api/author/10070765 Kovács Klaudia true true Kovacs Klaudia true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 98466585 /api/authorship/98466585 3 0.07692308 false false false Author 10074613 /api/author/10074613 Németh Orsolya true true Nemeth Orsolya true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 98466586 /api/authorship/98466586 4 0.077 false false false Author 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Institute 19060 /api/institute/19060 0 false true false Demográfiai Osztályközi Állandó Bizottság Committee on Demography true 19060 true true true A hazai false true SjrRating 11226931 /api/sjrrating/11226931 2012 1.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true Q4 DIRECT true true /api/publication/32367392 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10080625"><a href="/gui2/?type=authors&mode=browse&sel=10080625" target="_blank">Kormanyos Kitti ✉ (<span class="authorship-author-name">Kormányos Kitti</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10070765"><a href="/gui2/?type=authors&mode=browse&sel=10070765" target="_blank">Kovacs Klaudia (<span class="authorship-author-name">Kovács Klaudia</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10074613"><a href="/gui2/?type=authors&mode=browse&sel=10074613" target="_blank">Nemeth Orsolya (<span class="authorship-author-name">Németh Orsolya</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil">Vas Megyei Markusovszky Kórház Nonprofit Zrt.</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037478"><a href="/gui2/?type=authors&mode=browse&sel=10037478" target="_blank">Tóth Gabor (<span class="authorship-author-name">Tóth Gábor</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10025699"><a href="/gui2/?type=authors&mode=browse&sel=10025699" target="_blank">Sandor Gabor Laszlo (<span class="authorship-author-name">Sándor Gábor László</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10061200"><a href="/gui2/?type=authors&mode=browse&sel=10061200" target="_blank">Csorba Anita (<span class="authorship-author-name">Csorba Anita</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10046209"><a href="/gui2/?type=authors&mode=browse&sel=10046209" target="_blank">Czakó Cecilia Nora (<span class="authorship-author-name">Czakó Cecilia Nóra</span> <span class="authorAux-mtmt"> szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Langenbucher Achim </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10009641"><a href="/gui2/?type=authors&mode=browse&sel=10009641" target="_blank">Nagy Zoltan Zsolt (<span class="authorship-author-name">Nagy Zoltán Zsolt</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10045995"><a href="/gui2/?type=authors&mode=browse&sel=10045995" target="_blank">Varga Gergely (<span class="authorship-author-name">Varga Gergely</span> <span class="authorAux-mtmt"> hematológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/III. Department of Internal Medicine</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10066903"><a href="/gui2/?type=authors&mode=browse&sel=10066903" target="_blank">Gopcsa Laszlo (<span class="authorship-author-name">Gopcsa László</span> <span class="authorAux-mtmt"> Belgyógyászat, hematológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10048765"><a href="/gui2/?type=authors&mode=browse&sel=10048765" target="_blank">Mikala Gabor (<span class="authorship-author-name">Mikala Gábor</span> <span class="authorAux-mtmt"> Hematológia</span>) </a> </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000048"><a href="/gui2/?type=authors&mode=browse&sel=10000048" target="_blank">Szentmary Nora (<span class="authorship-author-name">Szentmáry Nóra</span> <span class="authorAux-mtmt"> Szemészet</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Ophthalmology</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32367392" target="_blank">A monoklonális gammopathia szemészeti jelei és szövődményei : 42 beteg 84 szemének vizsgálata.</a></div> <div> <span class="journal-title">ORVOSI HETILAP</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0030-6002">0030-6002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1788-6120">1788-6120</a>)</span>: <span class="journal-volume">162</span> <span class="journal-issue">38</span> <span class="page"> pp 1533-1540 </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: Hungarian | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1556/650.2021.32228" target="_blank" href="https://doi.org/10.1556/650.2021.32228"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000697769600004" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000697769600004"> WoS </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:blue" title="145567" target="_blank" href="http://real.mtak.hu/145567"> REAL </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85116539026" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85116539026"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34537715" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34537715&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="3101898" target="_blank" href="https://matarka.hu/egy-kozlemeny-oldala.php?MatarkaID=3101898"> Matarka </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q4</div> <div class="journal-subject">Committee on Psychology HASSPHSII PsziTB [1901-]&nbsp;&nbsp;&nbsp;A</div> <div class="journal-subject">Committee on Demography HASSELIX DEM [1901-]&nbsp;&nbsp;&nbsp;A hazai</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 1</span> | Independent citation: 1 | Self citation: 0 | Unknown citation: 0 | Number of citations with DOI:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32367392&sort=publishedYear,desc&sort=title"> Number of cited publications: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 32367392</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2023.02.20. 18:29 Orsolya Németh (Szemészet) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Semmelweis Egyetem, Általános Orvostudományi Kar, Szemészeti Klinika, Budapest, Hungary Magyar Honvédség Egészségügyi Központ, Szemészeti Osztály, Budapest, Hungary Markusovszky Egyetemi Oktatókórház, Szemészeti Osztály, Szombathely, Hungary Experimental Ophthalmology, Saarland University, Saar, Homburg, Germany ...</pre> </div></div>