Owing to their excellent mechanical flexibility, mixed-conducting electrical property,
and extraordinary chemical turnability, conjugated polymers have been demonstrated
to be an ideal bioelectronic interface to deliver therapeutic effect in many different
chronic diseases. This review article summarizes the latest advances in implantable
electronics using conjugated polymers as electroactive materials and identifies remaining
challenges and opportunities for developing electronic medicine. Examples of conjugated
polymer-based bioelectronic devices are selectively reviewed in human clinical studies
or animal studies with the potential for clinical adoption. The unique properties
of conjugated polymers are highlighted and exemplified as potential solutions to address
the specific challenges in electronic medicine.
