{ "labelLang" : "hun", "responseDate" : "2024-03-28 16:32", "content" : { "otype" : "JournalArticle", "mtid" : 32228676, "status" : "VALIDATED", "published" : true, "comment" : "Funding Agency and Grant Number: National Key R&D Program of China [2018YFA01017302]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81873688]\n Funding text: This work was supported by the National Key R&D Program of China under Grant [number 2018YFA01017302]; the National Natural Science Foundation of China under Grant [number 81873688].\n Part number: 1", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2022-07-29T18:57:14.943+0000", "lastModified" : "2021-10-12T13:22:18.648+0000", "created" : "2021-09-22T11:58:13.990+0000", "creator" : { "otype" : "Admin", "mtid" : 10073918, "link" : "/api/admin/10073918", "label" : "Kovács Marcell (MTMT Közp., admin)", "familyName" : "Kovács", "givenName" : "Marcell", "published" : true, "snippet" : true }, "lastDuplumOK" : "2021-10-14T09:30:33.766+0000", "lastDuplumSearch" : "2021-10-14T09:30:33.766+0000", "validated" : "2021-10-12T13:22:18.596+0000", "validator" : { "otype" : "Admin", "mtid" : 10067876, "link" : "/api/admin/10067876", "label" : "MTMT API (MTMT API user, admin)", "familyName" : "MTMT", "givenName" : "API", "published" : true, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Szakcikk (Folyóiratcikk)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Li, Minghui", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 97593846, "link" : "/api/authorship/97593846", "label" : "Li, Minghui", "listPosition" : 1, "share" : 0.25, "first" : true, "last" : false, "corresponding" : false, "familyName" : "Li", "givenName" : "Minghui", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 97593847, "link" : "/api/authorship/97593847", "label" : "Yang, Tian", "listPosition" : 2, "share" : 0.25, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Yang", "givenName" : "Tian", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 97593848, "link" : "/api/authorship/97593848", "label" : "Gao, Lixiong", "listPosition" : 3, "share" : 0.25, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Gao", "givenName" : "Lixiong", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 97593849, "link" : "/api/authorship/97593849", "label" : "Xu, Haiwei ✉", "listPosition" : 4, "share" : 0.25, "first" : false, "last" : true, "corresponding" : true, "familyName" : "Xu", "givenName" : "Haiwei", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 19361420, "link" : "/api/publicationidentifier/19361420", "label" : "DOI: 10.1016/j.chemosphere.2020.128484", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1016/j.chemosphere.2020.128484", "realUrl" : "https://doi.org/10.1016%2Fj.chemosphere.2020.128484", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 19361421, "link" : "/api/publicationidentifier/19361421", "label" : "WoS: 000599817400067", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=@@@&DestApp=WOS", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000599817400067", "realUrl" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=000599817400067&DestApp=WOS", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 19361425, "link" : "/api/publicationidentifier/19361425", "label" : "Scopus: 85092317973", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "idValue" : "85092317973", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85092317973", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 19361422, "link" : "/api/publicationidentifier/19361422", "label" : "PubMed: 33022499", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "idValue" : "33022499", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33022499&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 998, "link" : "/api/journal/998", "label" : "CHEMOSPHERE 0045-6535 1879-1298", "pIssn" : "0045-6535", "eIssn" : "1879-1298", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 998, "snippet" : true }, "volume" : "264", "internalId" : "128484", "firstPageOrInternalIdForSort" : "128484", "pageLength" : 18, "publishedYear" : 2021, "abstractText" : "Endocrine disrupting chemicals (EDCs) are a group of chemical compounds that present a considerable public health problem due to their pervasiveness and associations with chronic diseases. EDCs can interrupt the endocrine system and interfere with hormone homeostasis, leading to abnormalities in human physiology. Much attention has been focused on the adverse effects EDCs have on the reproductive system, neurogenesis, neuroendocrine system, and thyroid dysfunction. The eye is usually directly exposed to the surrounding environment; however, the influences of EDCs on the eye have received comparatively little attention. Ocular diseases, such as ocular surface diseases and retinal diseases, have been implicated in hormone deficiency or excess. Epidemiologic studies have shown that EDC exposure not only causes ocular surface disorders, such as dry eye, but also associates with visual deficits and retinopathy. EDCs can pass through the human blood-retinal barrier and enter the neural retina, and can then accumulate in the retina. The retina is an embryologic extension of the central nervous system, and is extremely sensitive and vulnerable to EDCs that could be passed across the placenta during critical periods of retinal development. Subtle alterations in the retinal development process usually result in profound immediate, long-term, and delayed effects late in life. This review, based on extensive literature survey, briefly summarizes the current knowledge about the impact of representative manufactured EDCs on retinal toxicity, including retinal structure alterations and dysfunction. We also highlight the potential mechanism of action of EDCs on the retina, and the predictive retinal models of EDC exposure. (C) 2020 Elsevier Ltd. All rights reserved.", "keywords" : [ { "otype" : "Keyword", "mtid" : 6701, "link" : "/api/keyword/6701", "label" : "prenatal exposure", "published" : true, "oldId" : 6701, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1046262, "link" : "/api/keyword/1046262", "label" : "POLYCYCLIC AROMATIC-HYDROCARBONS", "published" : true, "oldId" : 1046262, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1052529, "link" : "/api/keyword/1052529", "label" : "NERVE-FIBER LAYER", "published" : true, "oldId" : 1052529, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1056334, "link" : "/api/keyword/1056334", "label" : "ENDOCRINE DISRUPTING CHEMICALS", "published" : true, "oldId" : 1056334, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1102944, "link" : "/api/keyword/1102944", "label" : "UMBILICAL-CORD BLOOD", "published" : true, "oldId" : 1102944, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1112656, "link" : "/api/keyword/1112656", "label" : "ARYL-HYDROCARBON RECEPTOR", "published" : true, "oldId" : 1112656, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1498517, "link" : "/api/keyword/1498517", "label" : "LONG-TERM EXPOSURE", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1517790, "link" : "/api/keyword/1517790", "label" : "PIGMENT EPITHELIAL-CELLS", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1520582, "link" : "/api/keyword/1520582", "label" : "POLYBROMINATED DIPHENYL ETHERS", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1819198, "link" : "/api/keyword/1819198", "label" : "IN-UTERO EXPOSURE", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1866364, "link" : "/api/keyword/1866364", "label" : "FATTY-ACID-METABOLISM", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 2365610, "link" : "/api/keyword/2365610", "label" : "Human retinal development", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2021, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2022-07-29", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 1, "citedCount" : 1, "ratings" : [ { "otype" : "SjrRating", "mtid" : 11217769, "link" : "/api/sjrrating/11217769", "label" : "sjr:D1 (2021) Scopus - Environmental Engineering CHEMOSPHERE 0045-6535", "listPos" : 11, "rankValue" : 0.1, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 2305, "link" : "/api/classificationexternal/2305", "label" : "Scopus - Environmental Engineering", "published" : true, "oldId" : 2305, "snippet" : true }, "ranking" : "D1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "D1", "mtaRatingsForSort" : "A", "hasCitationDuplums" : false, "userChangeableUntil" : "2021-12-21T13:01:10.469+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 8, "ownerInstituteCount" : 46, "directInstituteCount" : 0, "authorCount" : 4, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/32228676", "label" : "Li Minghui et al. An inadvertent issue of human retina exposure to endocrine disrupting chemicals: A safety assessment. (2021) CHEMOSPHERE 0045-6535 1879-1298 264", "template" : "