{ "labelLang" : "hun", "responseDate" : "2024-03-28 18:59", "content" : { "otype" : "JournalArticle", "mtid" : 3219635, "status" : "VALIDATED", "published" : true, "comment" : "Department of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 30 July 2019 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 3 February 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 13 February 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com \n Chemicals/CAS: acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; amlodipine, 88150-42-9, 103129-82-4, 736178-83-9; bisoprolol, 66722-44-9; brain derived neurotrophic factor, 218441-99-7; carvedilol, 72956-09-3; doxazosin, 74191-85-8; losartan, 114798-26-4; metoprolol, 37350-58-6; nebivolol, 99200-09-6, 118457-15-1, 118457-16-2; perindopril, 82834-16-0, 99149-83-4; Antihypertensive Agents\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 20 March 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 14 July 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 14 September 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com \n Chemicals/CAS: acetylsalicylic acid, 493-53-8, 50-78-2, 53663-74-4, 53664-49-6, 63781-77-1; amlodipine, 88150-42-9, 103129-82-4, 736178-83-9; bisoprolol, 66722-44-9; brain derived neurotrophic factor, 218441-99-7; carvedilol, 72956-09-3; doxazosin, 74191-85-8; losartan, 114798-26-4; metoprolol, 37350-58-6; nebivolol, 99200-09-6, 118457-15-1, 118457-16-2; perindopril, 82834-16-0, 99149-83-4; Antihypertensive Agents\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 22 September 2020 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :2 \n Export Date: 3 March 2021 \n Correspondence Address: Nemcsik, J.Mecset utca 17. II/25A, Hungary; email: janos.nemcsik@gmail.com\nDepartment of Family Medicine, Semmelweis University, Budapest, Hungary \n TCM-Klinik Bad Kötzting, Germany \n 1st Department of Medicine, Semmelweis University, Budapest, Hungary \n Department of Epidemiology and Public Health, University College London, London, United Kingdom \n MTA-SE “Lendület” Diabetes Research Group, Budapest, Hungary \n Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary \n Magnetic Resonance Imaging Research Center, Semmelweis University, Budapest, Hungary \n Department of Pharmacodynamics, Semmelweis University, Budapest, Hungary \n Department of Psychiatry and Psychotherapy, Semmelweis University, Budapest, Hungary \n MTA-SE Neurochemistry Research Group, Budapest, Hungary \n Health Service of Zugló (ZESZ), Budapest, Hungary \n Cited By :3 \n Export Date: 15 April 2021 \n Correspondence Address: Nemcsik, J.Mecset utca 17. 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The aim of this study was to evaluate the effect of current antihypertensive medication on different psychometric parameters and on serum brain-derived neurotrophic factor (BDNF) level. METHODS: Psychometric, haemodynamic, arterial stiffness and laboratory parameters were evaluated before and 3 months after the initiation of antihypertensive medication in untreated hypertensive patients (HT, n=31), and once in healthy controls (CONT, n=22). Subjects completed the following psychometric tests: Beck Depression Inventory (BDI), Hamilton Anxiety Scale (HAM-A), Symptom Checklist 90 Revised (SCL-90), Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire, Big Five Inventory, Pain Vigilance and Awareness Questionnaire and Berkeley Expressivity Questionnaire. Amlodipine and/or perindopril compounds were preferred medications. Serum BDNF was measured with ELISA. RESULTS: Brachial systolic blood pressure, as well as pulse wave velocity were significantly improved in the HT group over the 3-month follow-up (153.3+/-15.9 mmHg vs. 129.5+/-10.0 mmHg and 8.2+/-1.4 m/s vs 7.5+/-1.6 m/s, respectively). Similarly, we found improvements in BDI (0.73 points) and in several Scl-90 subscales. Serum BDNF was not different between CONT and HT and did not change for therapy. CONCLUSIONS: Our results indicate that initiation of currently recommended antihypertensive medications in newly diagnosed patients may have a significant impact on psychological well-being of patients and could influence quality of life as well.", "subjects" : [ { "otype" : "Classification", "mtid" : 12125, "link" : "/api/classification/12125", "label" : "Általános orvostudomány", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Klinikai orvostan", "published" : true, "snippet" : true }, { "otype" : "Classification", "mtid" : 12741, "link" : "/api/classification/12741", "label" : "Pszichológia", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2017, "packet" : "640484", "foreignEdition" : false, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : true, "missingAuthor" : false, "oaType" : "GREEN", 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