https://m2.mtmt.hu/ hun 2026-09-23 09:51 JournalArticle 3217510 APPROVED true 0 2018-07-02T22:21:18.000+0000 false 3217510 2026-09-13T22:23:55.443+0000 2018-12-06T12:15:35.722+0000 2017-05-03T09:55:29.000+0000 true 10004870 Géher Pál /api/author/10004870 Author true 10004870 2024-10-18T06:42:21.536+0000 2024-10-18T06:42:21.536+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1404735 Report true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1404735 Jelentés SubType 112 true 1404735 true 1 /api/category/1 Category true 1 van der Heijde, D 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. true true /api/journal/383 REVIEWED true false 383 false 383 true 0003-4967 1468-2060 Journal FOREIGN 76 6 978 991 978 14 2017 To update and integrate the recommendations for ankylosing spondylitis and the recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial spondyloarthritis (axSpA) into one set applicable to the full spectrum of patients with axSpA. Following the latest version of the European League Against Rheumatism (EULAR) Standardised Operating Procedures, two systematic literature reviews first collected the evidence regarding all treatment options (pharmacological and non-pharmacological) that were published since 2009. After a discussion of the results in the steering group and presentation to the task force, overarching principles and recommendations were formulated, and consensus was obtained by informal voting. A total of 5 overarching principles and 13 recommendations were agreed on. The first three recommendations deal with personalised medicine including treatment target and monitoring. Recommendation 4 covers non-pharmacological management. Recommendation 5 describes the central role of non-steroidal anti-inflammatory drugs (NSAIDs) as first-choice drug treatment. Recommendations 6-8 define the rather modest role of analgesics, and disprove glucocorticoids and conventional synthetic disease-modifying antirheumatic drugs (DMARDs) for axSpA patents with predominant axial involvement. Recommendation 9 refers to biological DMARDs (bDMARDs) including TNFi and IL-17 inhibitors (IL-17i) for patients with high disease activity despite the use (or intolerance/contraindication) of at least two NSAIDs. In addition, they should either have an elevated C reactive protein and/or definite inflammation on MRI and/or radiographic evidence of sacroiliitis. Current practice is to start with a TNFi. Switching to another TNFi or an IL-17i is recommended in case TNFi fails (recommendation 10). Tapering, but not stopping a bDMARD, can be considered in patients in sustained remission (recommendation 11). The final two recommendations (12, 13) deal with surgery and spinal fractures. The 2016 Assessment of SpondyloArthritis international Society-EULAR recommendations provide up-to-date guidance on the management of patients with axSpA. 2017 (Géher Pál (Reumatológia); 2017.05.03. 11:54:20) true true false false true false NONE 2026-09-14 false 1117 1 1117 824 11 1117 1066 1108 722 1117 1117 824 824 824 293 0 1117 824 1117 824 0 6 6 Folyóiratcikk Journal Article 24 1117 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2017 0 37 28 37 28 2018 0 89 48 89 48 2019 0 159 116 159 116 2020 0 162 113 162 113 2021 0 167 124 167 124 2022 0 212 156 212 156 2023 0 132 104 132 104 2024 0 87 72 87 72 2025 0 52 44 52 44 2026 0 20 19 20 19 false false false false 2017-08-04T12:22:49.000+0000 2017-05-06T12:22:49.000+0000 III. 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Classification 10545 /api/classification/10545 true true Classification 12215 /api/classification/12215 true true /api/publication/3217510 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >van der Heijde D </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ramiro S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Landewe R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Baraliakos X </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Van den Bosch F </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sepriano A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Regel A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ciurea A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Dagfinrud H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Dougados M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van Gaalen F </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10004870"><a href="/gui2/?type=authors&mode=browse&sel=10004870" target="_blank">Geher P (<span class="authorship-author-name">Géher Pál</span> <span class="authorAux-mtmt"> Reumatológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/III. 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Belgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van der Horst-Bruinsma I </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Inman RD </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Jongkees M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kiltz U </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kvien TK </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Machado PM </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Marzo-Ortega H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Molto A </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Navarro-Compan V </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ozgocmen S </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Pimentel-Santos FM </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Reveille J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Rudwaleit M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sieper J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sampaio-Barros P </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Wiek D </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Braun J </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3217510" target="_blank">2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis.</a></div> <div> <span class="journal-title">ANNALS OF THE RHEUMATIC DISEASES</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0003-4967">0003-4967</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1468-2060">1468-2060</a>)</span>: <span class="journal-volume">76</span> <span class="journal-issue">6</span> <span class="page"> pp 978-991 </span> <span class="year">(2017)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1136/annrheumdis-2016-210770" target="_blank" href="https://doi.org/10.1136/annrheumdis-2016-210770"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000401138800010" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000401138800010"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85011039422" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85011039422"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="28087505" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28087505&dopt=Abstract"> PubMed </a> </span> </span> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1,117</span> | Független: 824 | Függő: 293 | Nem jelölt: 0 | WoS jelölt: 1,108 | Scopus jelölt:&nbsp;722 | WoS/Scopus jelölt:&nbsp;1,117 | DOI jelölt:&nbsp;1,066 (Nem nyilvános:&nbsp;1) </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3217510&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3217510</span> | <span class="status-data status-APPROVED"> Nyilvános </span> <span class="oldId">Régi azonosító: 3217510</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Jelentés ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2018.12.06. 13:15 Vasvari Lilian (MTMT Központ, admin) </div> </div></div>