https://m2.mtmt.hu/ hun 2026-10-25 00:03 JournalArticle 32128666 VALIDATED true Funding Agency and Grant Number: Vericel Corporation [20180814] Funding text: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The funding was provided by Vericel Corporation (Grant Id 20180814). Supplement: 1_ 0 false 2026-10-21T14:41:22.739+0000 2022-03-07T14:15:13.344+0000 2021-08-10T15:54:23.809+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Molnár-Taga Márta (SE 4-es admin) true 10062250 2025-03-24T12:37:28.494+0000 2022-03-07T14:15:13.352+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin Molnár-Taga Márta (SE 4-es admin) true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Mestriner, A.B. true true /api/journal/10020327 REVIEWED CARTILAGE 1947-6035 1947-6043 true false 10020327 false 10020327 true 1947-6035 1947-6043 Journal FOREIGN 13 Suppl. 1 1298S 1305S 1298S 2021 Objective: To determine the relationship between cartilage lesion etiology and clinical outcomes after second-generation autologous chondrocyte implantation (ACI) in the patellofemoral joint (PFJ) with a minimum of 2 years’ follow-up. Methods: A retrospective review of all patients that underwent ACI in the PFJ by a single surgeon was performed. Seventy-two patients with a mean follow-up of 4.2 ± 2.0 years were enrolled in this study and were stratified into 3 groups based on the etiology of PFJ cartilage lesions: patellar dislocation (group 1; n = 23); nontraumatic lesions, including chondromalacia, osteochondritis dissecans, and degenerative defects (group 2; n = 28); and other posttraumatic lesions besides patellar dislocations (group 3; n = 21). Patient’s mean age was 29.6 ± 8.7 years. Patients in group 1 were significantly younger (25.4 ± 7.9 years) than group 2 (31.7 ± 9.6 years; P = 0.025) and group 3 (31.5 ± 6.6 years; P = 0.05). Body mass index averaged 26.2 ± 4.3 kg/m2, with a significant difference between group 1 (24.4 ± 3.2 kg/m2) and group 3 (28.7 ± 4.5 kg/m2; P = 0.005). A clinical comparison was established between groups based on patient-reported outcome measures (PROMs) and failure rates. Results: Neither pre- nor postoperative PROMs differed between groups (P > 0.05). No difference was seen in survivorship between groups (95.7% vs. 82.2% vs. 90.5%, P > 0.05). Conclusion: Cartilage lesion etiology did not influence clinical outcome in this retrospective study after second generation ACI in the PFJ. Level of Evidence: Level III, retrospective comparative study. © The Author(s) 2021. true 2021 true true true false true false NONE 2026-10-21 false 1 0 1 1 0 1 1 1 0 1 1 1 1 1 0 0 1 1 1 1 0 3 3 Folyóiratcikk Journal Article 24 1 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2024 0 1 1 1 1 Q2 false false false false 2021-11-08T16:56:09.554+0000 Traumatológiai Tanszék (SE / AOK / K) 1 13 1 6 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 97005485 /api/authorship/97005485 Mestriner, A.B. ✉ 1 0.16666667 true false true Mestriner A.B. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 97005486 /api/authorship/97005486 Ackermann, J. 2 0.16666667 false false false Ackermann J. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 97005487 /api/authorship/97005487 Merkely, G. [Merkely, Gergő (ortopédia), szerző] Traumatológiai Tanszék (SE / AOK / K) 3 0.167 false false false Author 10051885 /api/author/10051885 Merkely Gergő (ortopédia) Merkely Gergő true 10051885 true Merkely G. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 97005488 /api/authorship/97005488 Galvão, P.H.S.A.F. 4 0.16666667 false false false Galvão P.H.S.A.F. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 97005489 /api/authorship/97005489 Ambra, L.F.M. 5 0.16666667 false false false Ambra L.F.M. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 97005490 /api/authorship/97005490 Gomoll, A.H. 6 0.16666667 false true false Gomoll A.H. true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 19081228 /api/publicationidentifier/19081228 DOI: 10.1177/19476035211030991 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true IDENTICAL 10.1177/19476035211030991 https://doi.org/10.1177/19476035211030991 false true PublicationIdentifier 19081229 /api/publicationidentifier/19081229 WoS: 000676847000001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000676847000001 https://www.webofscience.com/wos/woscc/full-record/000676847000001 false true PublicationIdentifier 19081227 /api/publicationidentifier/19081227 Scopus: 85111019530 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85111019530 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85111019530 false true PublicationIdentifier 19081230 /api/publicationidentifier/19081230 PubMed: 34286619 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 34286619 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34286619&dopt=Abstract false true Keyword 1500417 /api/keyword/1500417 AUTOLOGOUS CHONDROCYTE IMPLANTATION true true Keyword 1526025 /api/keyword/1526025 cartilage repair true true Keyword 1922300 /api/keyword/1922300 Patellofemoral joint true true SjrRating 11212773 /api/sjrrating/11212773 sjr:Q2 (2021) Scopus - Biomedical Engineering CARTILAGE 1947-6035 88 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2204 /api/classificationexternal/2204 Scopus - Biomedical Engineering true 2204 true Q2 DIRECT true true Reference 22113096 /api/reference/22113096 1. Kujala, U.M., Jaakkola, L.H., Koskinen, S.K., Taimela, S., Hurme, M., Nelimarkka, O., Scoring of patellofemoral disorders (1993) Arthroscopy, 9. , 159-63 1 false true Reference 22113095 /api/reference/22113095 2. Martincic, D., Mekac, J., Drobnic, M., Survival rates of various autologous chondrocyte grafts and concomitant procedures. A prospective single-center study over 18 years (2019) Cell Transplant, 28. , 1439-44 2 false true Reference 22113094 /api/reference/22113094 3. Behery, O., Siston, R.A., Harris, J.D., Flanigan, D.C., Treatment of cartilage defects of the knee: expanding on the existing algorithm (2014) Clin J Sport Med, 24, pp. 21-30 3 false true Reference 22113093 /api/reference/22113093 4. Farr, J., Autologous chondrocyte implantation improves patellofemoral cartilage treatment outcomes (2007) Clin Orthop Relat Res, 463. , 187-94 4 false true Reference 22113092 /api/reference/22113092 5. Pascual-Garrido, C., Slabaugh, M.A., L’Heureux, D.R., Friel, N.A., Cole, B.J., Recommendations and treatment outcomes for patellofemoral articular cartilage defects with autologous chondrocyte implantation: prospective evaluation at average 4-year follow-up (2009) Am J Sports Med, 37. , (,): 33S-41S 5 false true Reference 22113091 /api/reference/22113091 6. Gomoll, A.H., Gillogly, S.D., Cole, B.J., Farr, J., Arnold, R., Hussey, K., Autologous chondrocyte implantation in the patella: a multicenter experience (2014) Am J Sports Med, 42. , 1074-81 6 false true Reference 22113090 /api/reference/22113090 7. Schorn, D., Yang-Strathoff, S., Gosheger, G., Vogler, T., Klingebiel, S., Rickert, C., Long-term outcomes after combined arthroscopic medial reefing and lateral release in patients with recurrent patellar instability—a retrospective analysis (2017) BMC Musculoskelet Disord, 18, p. 277 7 false true Reference 22113089 /api/reference/22113089 8. Hinckel, B.B., Gomoll, A.H., Patellofemoral cartilage restoration: indications, techniques, and outcomes of autologous chondrocytes implantation, matrix-induced chondrocyte implantation, and particulated juvenile allograft cartilage (2018) J Knee Surg, 31. , 212-26 8 false true Reference 22113088 /api/reference/22113088 9. Ogura, T., Bryant, T., Merkely, G., Minas, T., Autologous chondrocyte implantation for bipolar chondral lesions in the patellofemoral compartment: clinical outcomes at a mean 9 years’ follow-up (2019) Am J Sports Med, 47. , 837-46 9 false true Reference 22113087 /api/reference/22113087 10. Peterson, L., Minas, T., Brittberg, M., Nilsson, A., Sjögren-Jansson, E., Lindahl, A., Two- to 9-year outcome after autologous chondrocyte transplantation of the knee (2000) Clin Orthop Relat Res, , (,):212-34 10 false true Reference 22113086 /api/reference/22113086 11. Brittberg, M., Lindahl, A., Nilsson, A., Ohlsson, C., Isaksson, O., Peterson, L., Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation (1994) N Engl J Med, 331. , 889-95 11 false true Reference 22113085 /api/reference/22113085 12. Cohen, J., (1988) Statistical Power Analysis for the Behavioral Sciences, p. 567. , 2nd ed., Lawrence Erlbaum Associates 12 false true Reference 22113084 /api/reference/22113084 13. Ackermann, J., Merkely, G., Mestriner, A.B., Shah, N., Gomoll, A.H., Increased chondrocytic gene expression is associated with improved repair tissue quality and graft survival in patients after autologous chondrocyte implantation (2019) Am J Sports Med, 47. , 2919-26 13 false true Reference 22113083 /api/reference/22113083 14. Ackermann, J., Barbieri Mestriner, A., Arango, D., Ogura, T., Gomoll, A.H., Validation of the Oswestry Risk of Knee Arthroplasty Index (ORKA-1) for patients undergoing autologous chondrocyte implantation (2020) Cartilage, 11. , 405-11 14 false true Reference 22113082 /api/reference/22113082 15. Harris, J.D., Brand, J.C., Cote, M.P., Faucett, S.C., Dhawan, A., Research pearls: the significance of statistics and perils of pooling. Part 1: clinical versus statistical significance (2017) Arthroscopy, 33. , 1102-12 15 false true Reference 22113081 /api/reference/22113081 16. Ogura, T., Ackermann, J., Mestriner, A.B., Merkely, G., Gomoll, A.H., Minimal clinically important differences and substantial clinical benefit in patient-reported outcome measures after autologous chondrocyte implantation (2020) Cartilage, 11, pp. 412-422 16 false true Reference 22113080 /api/reference/22113080 17. Jungmann, P.M., Salzmann, G.M., Schmal, H., Pestka, J.M., Südkamp, N.P., Niemeyer, P., Autologous chondrocyte implantation for treatment of cartilage defects of the knee: what predicts the need for reintervention? (2012) Am J Sports Med, 40, pp. 58-67 17 false true Reference 22113079 /api/reference/22113079 18. Gobbi, A., Kon, E., Berruto, M., Filardo, G., Delcogliano, M., Boldrini, L., Patellofemoral full-thickness chondral defects treated with second-generation autologous chondrocyte implantation: results at 5 years’ follow-up (2009) Am J Sports Med, 37. , 1083-92 18 false true Reference 22113078 /api/reference/22113078 19. Krishnan, S.P., Skinner, J.A., Bartlett, W., Carrington, R.W.J., Flanagan, A.M., Briggs, T.W.R., Who is the ideal candidate for autologous chondrocyte implantation? (2006) J Bone Joint Surg Br, 88. , 61-4 19 false true Reference 22113077 /api/reference/22113077 20. Yanke, A.B., Wuerz, T., Saltzman, B.M., Butty, D., Cole, B.J., Management of patellofemoral chondral injuries (2014) Clin Sports Med, 33, pp. 477-500 20 false true Reference 22113076 /api/reference/22113076 21. Behery, O.A., Harris, J.D., Karnes, J.M., Siston, R.A., Flanigan, D.C., Factors influencing the outcome of autologous chondrocyte implantation: a systematic review (2013) J Knee Surg, 26. , 203-11 21 false true Reference 22113075 /api/reference/22113075 22. Peterson, L., Vasiliadis, H.S., Brittberg, M., Lindahl, A., Autologous chondrocyte implantation: a long-term follow-up (2010) Am J Sports Med, 38. , 1117-24 22 false true Reference 22113074 /api/reference/22113074 23. von Keudell, A., Han, R., Bryant, T., Minas, T., Autologous chondrocyte implantation to isolated patella cartilage defects (2017) Cartilage, 8. , 146-54 23 false true Reference 22113073 /api/reference/22113073 24. Vasiliadis, H.S., Lindahl, A., Georgoulis, A.D., Peterson, L., Malalignment and cartilage lesions in the patellofemoral joint treated with autologous chondrocyte implantation (2011) Knee Surg Sports Traumatol Arthrosc, 19. , 452-7 24 false true Reference 22113072 /api/reference/22113072 25. Ambra, L.F., Hinckel, B.B., Arendt, E.A., Farr, J., Gomoll, A.H., Anatomic risk factors for focal cartilage lesions in the patella and trochlea: a case-control study (2019) Am J Sports Med, 47. , 2444-53 25 false true Reference 22113071 /api/reference/22113071 26. Gomoll, A.H., Ambra, L.F., Phan, A., Mastrocola, M., Shah, N., Cell-seeded autologous chondrocyte implantation: a simplified implantation technique that maintains high clinical outcomes (2017) Am J Sports Med, 45. , 1028-36 26 false true Reference 22113070 /api/reference/22113070 27. Mestriner, A.B., Ackermann, J., Gomoll, A.H., Patellofemoral cartilage repair (2018) Curr Rev Musculoskelet Med, 11, pp. 188-200 27 false true Reference 22113069 /api/reference/22113069 28. Gomoll, A.H., Minas, T., Farr, J., Cole, B.J., Treatment of chondral defects in the patellofemoral joint (2006) J Knee Surg, 19. , 285-95 28 false true Reference 22113068 /api/reference/22113068 29. Nomura, E., Inoue, M., Kurimura, M., Chondral and osteochondral injuries associated with acute patellar dislocation (2003) Arthroscopy, 19. , 717-21 29 false true Reference 22113067 /api/reference/22113067 30. Hart, H.F., Stefanik, J.J., Wyndow, N., Machotka, Z., Crossley, K.M., The prevalence of radiographic and MRI-defined patellofemoral osteoarthritis and structural pathology: a systematic review and meta-analysis (2017) Br J Sports Med, 51. , 1195-208 30 false true Reference 22113066 /api/reference/22113066 31. Kobayashi, S., Pappas, E., Fransen, M., Refshauge, K., Simic, M., The prevalence of patellofemoral osteoarthritis: a systematic review and meta-analysis (2016) Osteoarthritis Cartilage, 24. , 1697-707 31 false true /api/publication/32128666 Mestriner A.B. et al. Etiology of Cartilage Lesions Does Not Affect Clinical Outcomes of Patellofemoral Autologous Chondrocyte Implantation. (2021) CARTILAGE 1947-6035 1947-6043 13 Suppl. 1 1298S-1305S<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Mestriner A.B. ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ackermann J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10051885"><a href="/gui2/?type=authors&mode=browse&sel=10051885" target="_blank">Merkely G. (<span class="authorship-author-name">Merkely Gergő</span> <span class="authorAux-mtmt"> ortopédia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Traumatológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Galvão P.H.S.A.F. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ambra L.F.M. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gomoll A.H. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32128666" target="_blank">Etiology of Cartilage Lesions Does Not Affect Clinical Outcomes of Patellofemoral Autologous Chondrocyte Implantation</a></div> <div> <span class="journal-title">CARTILAGE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6035">1947-6035</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6043">1947-6043</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">Suppl. 1</span> <span class="page"> pp 1298S-1305S </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1177/19476035211030991" target="_blank" href="https://doi.org/10.1177/19476035211030991"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000676847000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000676847000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85111019530" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85111019530"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="34286619" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=34286619&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biomedical Engineering&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical Therapy, Sports Therapy and Rehabilitation&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;32128666&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32128666</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Utolsó módosítás: 2022.03.07. 15:15 Molnár-Taga Márta (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Funding Agency and Grant Number: Vericel Corporation [20180814] Funding text: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The funding was provided by Vericel Corporation (Grant Id 20180814). Supplement: 1_</pre> </div></div>