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email: arianna.tavanti@unipi.it\nDepartment of Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, 8600, Switzerland \n Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, 56127, Italy \n Department of Biology, University of Pisa, Pisa, 56127, Italy \n Export Date: 17 August 2021 \n Correspondence Address: Tavanti, A.; Department of Biology, Italy; email: arianna.tavanti@unipi.it\nDepartment of Environmental Toxicology, Eawag, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, 8600, Switzerland \n Department of Chemistry and Industrial Chemistry, University of Pisa, Pisa, 56127, Italy \n Department of Biology, University of Pisa, Pisa, 56127, Italy \n Export Date: 18 August 2021 \n Correspondence Address: Tavanti, A.; Department of Biology, Italy; email: arianna.tavanti@unipi.it", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2024-01-03T15:24:22.940+0000", "lastModified" : 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In this regard, the present review “draws a line” on the information acquired, thus far, on virulence determinants and molecular mechanisms of antifungal resistance in these opportunistic pathogens, mainly derived from genetic manipulation studies. This will provide better focus on where we stand in our understanding of the C. parapsilosis species complex–host interaction, and how far we are from defining potential novel targets or therapeutic strategies—key factors to pave the way for a more tailored management of fungal infections caused by these fungal pathogens. © 2021 by the authors. 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