https://m2.mtmt.hu/ eng 2026-10-24 17:36 JournalArticle 32081424 VALIDATED true Institute for Stroke and Dementia Research, University Hospital, Ludwig Maximilians University Munich, Munich, Germany German Center for Neurodegenerative Diseases, Munich, Germany Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilians University Munich, Munich, Germany Center for Neuropathology and Prion Research, Ludwig Maximilians University Munich, Munich, Germany Momentum Laboratory of Neuroimmunology, Institute of Experimental Medicine, Budapest, Hungary ELKH-DE Cerebrovascular and Neurodegenerative Research Group, Department of Neurology, University of Debrecen, Debrecen, Hungary University of Kentucky, Lexington, KY, United States Munich Cluster for Systems Neurology (SyNergy), Munich, Germany Cited By :8 Export Date: 4 May 2022 CODEN: JEMEA Correspondence Address: Liesz, A.; Institute for Stroke and Dementia Research, Germany; email: arthur.liesz@med.uni-muenchen.de Chemicals/CAS: alpha4 integrin, 355485-74-4; natalizumab, 189261-10-7; Integrin alpha4; Natalizumab Funding details: 2017-1.2.1-NKP-2017-00002 Funding details: National Institutes of Health, NIH, P30 AG028383 Funding details: American Heart Association, AHA, 19EIA34760279 Funding details: European Research Council, ERC, ERC-PoC 875677, ERC-StGs 802305 Funding details: Deutsche Forschungsgemeinschaft, DFG, 390857198, 408885537, LI-2534/6-1, LI-2534/7-1 Funding details: NOMIS Stiftung Funding text 1: We would like to thank Kerstin Thuβ-Silczak and Christina Fürle for technical support as well as Juliet Stowe for the selection and preparation of human tissue samples from the Sanders Brown Center on Aging (supported by National Institutes of Health grant P30 AG028383). Funding text 2: This work was funded by the European Research Council (grant ERC-StGs 802305 to A. Liesz and grant ERC-PoC 875677 to D. Ed-bauer), the American Heart Association (grant 19EIA34760279 to A.M. Stowe), the Hungarian Brain Research Program (grant 2017-1.2.1-NKP-2017-00002), and the German Research Foundation under Germany’s Excellence Strategy (EXC 2145 SyNergy, ID 390857198) through the collaborative research center TRR274 (project ID 408885537) and under grants LI-2534/6-1 and LI-2534/7-1. D. 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