https://m2.mtmt.hu/ hun 2026-10-25 12:46 JournalArticle 32061740 VALIDATED true 0 false 2026-10-21T10:37:43.353+0000 2024-07-28T16:55:17.347+0000 2021-06-08T12:37:23.165+0000 true 10074913 Sághi-Keszthelyi Anna /api/admin/10074913 Admin Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin) true 2024-07-28T16:55:17.359+0000 2024-07-28T16:55:17.359+0000 2021-06-08T13:07:19.495+0000 true 10074913 Sághi-Keszthelyi Anna /api/admin/10074913 Admin Sághi-Keszthelyi Anna (SE_KK_Admin5_SKA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Folyóiratcikk 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Szakcikk (Folyóiratcikk) 101 true 10000059 true 1 /api/category/1 Category Tudományos true 1 Jarecki, Jaromir true true /api/journal/10017543 REVIEWED JOURNAL OF CLINICAL MEDICINE 2077-0383 true false 10017543 false 10017543 true 2077-0383 Journal FOREIGN 10 6 1263 1263 12 2021 The aim of this study was to assess levels of adiponectin (ACRP-30) and leptin in serum and synovial fluid (SF) of overweight females with primary gonarthrosis (GOA) and to look for their correlations with clinical status and the level of biochemical OA biomarkers: matrix metalloproteinase (MMP) 1, MMP-9 and tissue inhibitor of metalloproteinase (TIMP-1). The studied group consisted of 39 overweight females undergoing primary total knee arthroplasty as a result of GOA. The stage of GOA was evaluated according to Knee Society Score (KSS), Ahlback and Kellgren-Lawrence (K-L) scores. Peripheral blood and SF were obtained. Levels of selected biomarkers were assessed using ELISA kits. The mean level of ACRP-30 in serum valued were 8393.80 ng/mL and in SF, 774.33 ng/mL, the mean concentration of leptin in serum was 32,040.74 pg/mL and in SF, 27,332.12 pg/mL. Levels of leptin in serum and SF correlated with body mass index (BMI), (p = 0.0005, and p = 0.0002, respectively). Levels of ACRP-30 in serum was correlated with clinical scores (Ahlback: p = 0.0214; K-L: p = 0.0146). ACRP-30 in SF correlated with ACRP-30 in serum (p = 0.0003), tended to negatively correlate with MMP-1 in serum (p = 0.0598) and positively correlate with pro-MMP-1 in SF (p = 0.0600). To conclude, this study confirms the correlations between concentrations of both, leptin and ACRP-30, comparing serum and SF. In overweight females, leptin levels increase with BMI and ACRP-30 serum level increase in more advanced GOA stages. Finally, leptin levels were correlated with TIMP-1 serum concentration, one of the biochemical markers of GOA. 2021 true true true false true false GOLD 2026-10-21 true https://doi.org/10.3390/jcm10061263 8 0 8 5 0 8 8 8 1 8 8 5 5 5 3 0 8 5 8 5 0 0 0 Folyóiratcikk Journal Article 24 8 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2022 0 1 0 1 0 2023 0 4 2 4 2 2024 0 2 2 2 2 2025 0 1 1 1 1 Q1 false false false false 2021-06-07T13:07:19.263+0000 Traumatológiai Tanszék (SE / AOK / K) 1 7 1 10 0 true Language 10002 /api/language/10002 Angol Angol English true 2 true PersonAuthorship 96556632 /api/authorship/96556632 Jarecki, Jaromir ✉ 1 0.1 true false true Jarecki Jaromir true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556633 /api/authorship/96556633 Malecka-Massalska, Teresa 2 0.1 false false false Malecka-Massalska Teresa true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556634 /api/authorship/96556634 Polkowska, Izabela 3 0.1 false false false Polkowska Izabela true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556635 /api/authorship/96556635 Potoczniak, Bartosz 4 0.1 false false false Potoczniak Bartosz true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556636 /api/authorship/96556636 Kosior-Jarecka, Ewa 5 0.1 false false false Kosior-Jarecka Ewa true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556637 /api/authorship/96556637 Szerb, Imre [Szerb, Imre (ortopédia-traumat...), szerző] Traumatológiai Tanszék (SE / AOK / K) 6 0.1 false false false Author 10036891 /api/author/10036891 Szerb Imre (ortopédia-traumatológia) Szerb Imre true 10036891 true Szerb Imre true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556638 /api/authorship/96556638 Tomaszewska, Ewa 7 0.1 false false false Tomaszewska Ewa true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556639 /api/authorship/96556639 Gutbier, Martina 8 0.1 false false false Gutbier Martina true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556640 /api/authorship/96556640 Dobrzynski, Maciej 9 0.1 false false false Dobrzynski Maciej true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PersonAuthorship 96556641 /api/authorship/96556641 Blicharski, Tomasz 10 0.1 false true false Blicharski Tomasz true false false AuthorshipType 1 /api/authorshiptype/1 Szerző 0 true 0 true false true PublicationIdentifier 18907045 /api/publicationidentifier/18907045 DOI: 10.3390/jcm10061263 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3390/jcm10061263 https://doi.org/10.3390/jcm10061263 false true PublicationIdentifier 18907046 /api/publicationidentifier/18907046 WoS: 000652002900001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS 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Murphy G, 2008, NAT CLIN PRACT RHEUM, V4, P128, DOI 10.1038/ncprheum0727 50 false true /api/publication/32061740 Jarecki Jaromir et al. Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis. (2021) JOURNAL OF CLINICAL MEDICINE 2077-0383 10 6<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <div class="autype autype0"> <span class="author-name" >Jarecki Jaromir ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Malecka-Massalska Teresa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Polkowska Izabela </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Potoczniak Bartosz </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kosior-Jarecka Ewa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10036891"><a href="/gui2/?type=authors&mode=browse&sel=10036891" target="_blank">Szerb Imre (<span class="authorship-author-name">Szerb Imre</span> <span class="authorAux-mtmt"> ortopédia-traumatológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Traumatológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Tomaszewska Ewa </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gutbier Martina </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Dobrzynski Maciej </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Blicharski Tomasz </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;32061740" target="_blank">Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis</a></div> <div> <span class="journal-title">JOURNAL OF CLINICAL MEDICINE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2077-0383">2077-0383</a>)</span>: <span class="journal-volume">10</span> <span class="journal-issue">6</span> <span class="page"> Paper 1263. 12 p. </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3390/jcm10061263" target="_blank" href="https://doi.org/10.3390/jcm10061263"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000652002900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000652002900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85114066259" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85114066259"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33803785" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33803785&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 8</span> | Független: 5 | Függő: 3 | Nem jelölt: 0 | WoS jelölt: 8 | Scopus jelölt:&nbsp;1 | WoS/Scopus jelölt:&nbsp;8 | DOI jelölt:&nbsp;8 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 32061740</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Utolsó módosítás: 2024.07.28. 18:55 Balázsné Balogh Ildikó (xSE_AOK_Trauma_Admin5_BBI_INAKTÍV, admin) </div> </div></div>