Proximal humerus chondrosarcoma is a rare localization of the common primary malignant
cartilaginous tumor. Management is based on oncological surgical excision because
of the inherent resistance to chemotherapy and radiation therapy. The most important
prognostic factors with great impact on treatment strategy are histological grading
and localization of the tumor. Proximal humerus chondrosarcoma carries a slightly
better prognosis, especially for the low and moderate grade tumors. We present the
case of a young patient with proximal humerus chondrosarcoma surgically managed in
our Department, with the purpose of underlining the challenges posed by this localization
for oncological excision and reconstruction but also the importance of histological
grading for the treatment algorithm.
