https://m2.mtmt.hu/ hun 2026-09-22 02:41 JournalArticle 31963581 VALIDATED true M. El Mahdiui and J. Simon contributed equally and share first authorship 0 false 2026-08-07T10:25:27.869+0000 2026-01-29T14:46:02.860+0000 2021-04-13T17:20:36.963+0000 true 10074827 xBesenyődi xSzonja /api/admin/10074827 Admin true 2026-01-29T14:46:02.278+0000 2022-11-24T19:01:58.295+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 El Mahdiui, Mohammed Posterior Left Atrial Adipose Tissue Attenuation Assessed by Computed Tomography and Recurrence of Atrial Fibrillation after Catheter Ablation true true /api/journal/10011405 REVIEWED true false 10011405 false 10011405 true 1941-3149 1941-3084 Journal FOREIGN 14 4 404 411 e009135 404, e009135 8 2021 Background - Atrial fibrillation (AF) recurrence following catheter ablation remains high. Recent studies have shown a relation between epicardial adipose tissue (EAT) and AF. EAT secretes several pro- and anti-inflammatory adipokines that directly interact with the adjacent myocardium. The aim of the current study was to evaluate whether posterior left atrial (LA) adipose tissue attenuation, as marker of inflammation, is related to AF recurrences after catheter ablation. Methods - Consecutive patients with symptomatic AF referred for first AF catheter ablation who underwent CT were included. The total EAT and posterior LA adipose tissue were manually traced and adipose tissue was automatically recognized as tissue with Hounsfield units (HU) between -195 and -45. The attenuation value of the posterior LA adipose tissue was assessed and the population divided according to the mean HU value (-96.4 HU). Results - In total, 460 patients (66% male, age 61 ± 10 years) were included in the analysis. After a median follow-up of 18 months (IQR 6-32), 168 (37%) patients had AF recurrence. Patients with higher attenuation (≥-96.4 HU) of the posterior LA adipose tissue showed higher AF recurrence rates compared to patients with lower attenuation (<-96.4 HU) (log-rank test p=0.046). Univariate analysis showed an association between AF recurrence and higher posterior LA adipose tissue attenuation (≥-96.4 HU) (p<0.05). On multivariable analysis posterior LA adipose tissue attenuation (HR 1.26; 95% CI 0.90-1.76; p=0.181) remained a promising predictor of AF recurrence following catheter ablation. Conclusions - Posterior LA adipose tissue attenuation is a promising predictor of AF recurrence in patients who undergo catheter ablation. Higher adipose tissue attenuation might signal increased local inflammation and serve as an imaging biomarker of increased risk of AF recurrence. Funding 2008743 /api/funding/2008743 false true Funding 2008744 /api/funding/2008744 false true true true 2021 true true true false true false GOLD 2026-08-07 true https://doi.org/10.1161/CIRCEP.120.009135 57 0 57 52 3 57 57 54 55 57 57 52 52 52 5 0 57 52 57 52 0 1 1 Folyóiratcikk Journal Article 24 57 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2021 0 4 4 4 4 2022 0 11 8 11 8 2023 0 11 11 11 11 2024 0 13 12 13 12 2025 0 14 13 14 13 2026 0 4 4 4 4 D1 false 10032556 false false false 2021-05-03T07:34:22.260+0000 MTA-SE Lendület Kardiovaszkuláris Képalkotó Kut... (SE / AOK / K / OKK); Orvosi Képalkotó Klinika (SE / AOK / K); Radiológia Tanszék (SE / AOK / K / OKK); Sportorvostan Tanszék (SE / AOK / K); Városmajori Szív- és Érgyógyászati Klinika (SE / AOK / K) 7 32 5 15 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 95970348 /api/authorship/95970348 1 0.06666667 true false false El Mahdiui Mohammed true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970349 /api/authorship/95970349 2 0.067 true false false Author 10066081 /api/author/10066081 Simon Judit true true Simon Judit true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970350 /api/authorship/95970350 3 0.06666667 false false false Smit Jeff M true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970351 /api/authorship/95970351 4 0.06666667 false false false Kuneman Jurrien H true false false AuthorshipType 1 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true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970357 /api/authorship/95970357 10 0.067 false false false Author 10032556 /api/author/10032556 Szegedi Nándor true 10032556 true Szegedi Nándor true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970358 /api/authorship/95970358 11 0.067 false false false Author 10013950 /api/author/10013950 Gellér László Alajos true 10013950 true Gellér László true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970359 /api/authorship/95970359 12 0.06666667 false false false Delgado Victoria true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970360 /api/authorship/95970360 13 0.067 false false false Author 10002691 /api/author/10002691 Merkely Béla Péter true 10002691 true Merkely Bela true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970361 /api/authorship/95970361 14 0.06666667 false false false Bax Jeroen J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95970362 /api/authorship/95970362 15 0.067 false true true Author 10019530 /api/author/10019530 Maurovich-Horvat Pál true 10019530 true Maurovich-Horvat Pál true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 18650686 /api/publicationidentifier/18650686 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1161/CIRCEP.120.009135 https://doi.org/10.1161/CIRCEP.120.009135 false true PublicationIdentifier 18840663 /api/publicationidentifier/18840663 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS 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class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >El Mahdiui Mohammed </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10066081"><a href="/gui2/?type=authors&mode=browse&sel=10066081" target="_blank">Simon Judit<sup>*</sup> (<span class="authorship-author-name">Simon Judit</span> <span class="authorAux-mtmt"> intervenciós radiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Smit Jeff M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kuneman Jurrien H </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van Rosendael Alexander R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Steyerberg Ewout W </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van der Geest Rob J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10078836"><a href="/gui2/?type=authors&mode=browse&sel=10078836" target="_blank">Száraz Lili (<span class="authorship-author-name">Száraz Lili</span> <span class="authorAux-mtmt"> radiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10063814"><a href="/gui2/?type=authors&mode=browse&sel=10063814" target="_blank">Herczeg Szilvia (<span class="authorship-author-name">Herczeg Szilvia</span> <span class="authorAux-mtmt"> kardiológia, elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10032556"><a href="/gui2/?type=authors&mode=browse&sel=10032556" target="_blank">Szegedi Nándor (<span class="authorship-author-name">Szegedi Nándor</span> <span class="authorAux-mtmt"> Orvostudományok, Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013950"><a href="/gui2/?type=authors&mode=browse&sel=10013950" target="_blank">Gellér László (<span class="authorship-author-name">Gellér László Alajos</span> <span class="authorAux-mtmt"> Kardiológia, Elektrofiziológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Delgado Victoria </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002691"><a href="/gui2/?type=authors&mode=browse&sel=10002691" target="_blank">Merkely Bela (<span class="authorship-author-name">Merkely Béla Péter</span> <span class="authorAux-mtmt"> Kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Városmajori Szív- és Érgyógyászati Klinika">VAROSMAJOR_SZÍVÉRGYÓGY</span>/Sportorvostan Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Bax Jeroen J </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10019530"><a href="/gui2/?type=authors&mode=browse&sel=10019530" target="_blank">Maurovich-Horvat Pál ✉ (<span class="authorship-author-name">Maurovich-Horvat Pál</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Városmajori Szív- és Érgyógyászati Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Orvosi Képalkotó Klinika; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/Radiológia Tanszék; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Lendület Kardiovaszkuláris Képalkotó Kutatócsoport</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31963581" target="_blank">Posterior Left Atrial Adipose Tissue Attenuation Assessed by Computed Tomography and Recurrence of Atrial Fibrillation after Catheter Ablation</a></div> <div> <span class="journal-title">CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1941-3149">1941-3149</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1941-3084">1941-3084</a>)</span>: <span class="journal-volume">14</span> <span class="journal-issue">4</span> <span class="page"> pp 404-411 Paper e009135. </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1161/CIRCEP.120.009135" target="_blank" href="https://doi.org/10.1161/CIRCEP.120.009135"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000641549500004" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000641549500004"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85104595601" target="_blank" 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szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physiology (medical)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 57</span> | Független: 52 | Függő: 5 | Nem jelölt: 0 | WoS jelölt: 54 | Scopus jelölt:&nbsp;55 | WoS/Scopus jelölt:&nbsp;57 | DOI jelölt:&nbsp;57 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31963581&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 31963581</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> National Heart Program(NVKP-16-1-2016-0017) Támogató: NKFIH, Thematic Excellence Program (Semmelweis University)(2020-4.1.1.-TKP2020) Támogató: Innovációs és Technológiai Minisztérium </div> <div class="lastModified">Utolsó módosítás: 2026.01.29. 15:46 Maár-Sipos Edina (SE_AOK_OrvosiKepalkoto_Admin5_MSE, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: M. El Mahdiui and J. Simon contributed equally and share first authorship</pre> </div></div>