https://m2.mtmt.hu/ hun 2026-04-17 08:14 JournalArticle 31952296 APPROVED true 0 false 2025-12-30T22:55:55.479+0000 2023-01-17T08:04:02.412+0000 2021-04-06T11:21:47.724+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 2023-01-17T08:04:02.730+0000 2023-01-17T08:04:02.730+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Galderisi, S. EPA guidance on treatment of negative symptoms in schizophrenia true true /api/journal/12175 REVIEWED true false 12175 false 12175 true 0924-9338 1778-3585 Journal FOREIGN 64 1 e21 e21 15 2021 Negative symptoms of schizophrenia remain a major therapeutic challenge. The progress in the conceptualization and assessment is not yet fully reflected by treatment research. Nevertheless, there is a growing evidence base regarding the effects of biological and psychosocial interventions on negative symptoms. The importance of the distinction between primary and secondary negative symptoms for treatment selection might seem evident, but the currently available evidence remains limited. Good clinical practice is recommended for the treatment of secondary negative symptoms. Antipsychotic treatment should be optimized to avoid secondary negative symptoms due to side effects and due to positive symptoms. For most available interventions, further evidence is needed to formulate sound recommendations for primary, persistent, or predominant negative symptoms.However, based on currently available evidence recommendations for the treatment of undifferentiated negative symptoms (including both primary and secondary negative symptoms) are provided. Although it has proven difficult to formulate an evidence-based recommendation for the choice of an antipsychotic, a switch to a second-generation antipsychotic should be considered for patients who are treated with a first-generation antipsychotic. Antidepressant add-on to antipsychotic treatment is an option. Social skills training is recommended as well as cognitive remediation for patients who also show cognitive impairment. Exercise interventions also have shown promise. Finally, access to treatment and to psychosocial rehabilitation should be ensured for patients with negative symptoms. Overall, there is definitive progress in the field, but further research is clearly needed to develop specific treatments for negative symptoms. true 2021 true true true false true false GOLD 2025-12-30 true https://doi.org/10.1192/j.eurpsy.2021.13 158 0 157 113 2 156 156 148 130 158 157 113 113 113 45 0 158 113 157 113 0 4 4 Folyóiratcikk Journal Article 24 155 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 1 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 1 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2021 0 6 4 6 4 2022 0 34 22 34 22 2023 0 36 27 36 27 2024 0 45 33 45 33 2025 0 32 23 32 23 D1 false false false false 2021-04-05T11:26:10.356+0000 Pszichiátriai és Pszichoterápiás Klinika (SE / AOK / K) 1 6 1 13 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 95901428 /api/authorship/95901428 1 0.07692308 true false false Galderisi S. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901429 /api/authorship/95901429 2 0.077 false false true Kaiser S. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901430 /api/authorship/95901430 3 0.077 false false false Author 10005190 /api/author/10005190 Bitter István true 10005190 true Bitter I. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901431 /api/authorship/95901431 4 0.07692308 false false false Nordentoft M. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901432 /api/authorship/95901432 5 0.07692308 false false false Mucci A. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901433 /api/authorship/95901433 6 0.07692308 false false false Sabé M. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901434 /api/authorship/95901434 7 0.07692308 false false false Giordano G.M. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901435 /api/authorship/95901435 8 0.07692308 false false false Nielsen M.Ø. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901436 /api/authorship/95901436 9 0.07692308 false false false Glenthøj L.B. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901437 /api/authorship/95901437 10 0.07692308 false false false Pezzella P. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901438 /api/authorship/95901438 11 0.07692308 false false false Falkai P. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901439 /api/authorship/95901439 12 0.07692308 false false false Dollfus S. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 95901440 /api/authorship/95901440 13 0.07692308 false true false Gaebel W. true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 18620951 /api/publicationidentifier/18620951 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.1192/j.eurpsy.2021.13 https://doi.org/10.1192/j.eurpsy.2021.13 false true PublicationIdentifier 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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 33726883 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33726883&dopt=Abstract false true Keyword 151 /api/keyword/151 true 151 true Keyword 17828 /api/keyword/17828 true 17828 true Keyword 1068260 /api/keyword/1068260 true 1068260 true SjrRating 11233469 /api/sjrrating/11233469 49 0.1 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2738 /api/classificationexternal/2738 true 2738 true D1 DIRECT true true /api/publication/31952296 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Galderisi S. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Kaiser S. ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10005190"><a href="/gui2/?type=authors&mode=browse&sel=10005190" target="_blank">Bitter I. (<span class="authorship-author-name">Bitter István</span> <span class="authorAux-mtmt"> Elmekórtan</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Pszichiátriai és Pszichoterápiás Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Nordentoft M. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Mucci A. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sabé M. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Giordano G.M. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Nielsen M.Ø. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Glenthøj L.B. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Pezzella P. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Falkai P. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Dollfus S. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gaebel W. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31952296" target="_blank">EPA guidance on treatment of negative symptoms in schizophrenia</a></div> <div> <span class="journal-title">EUROPEAN PSYCHIATRY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0924-9338">0924-9338</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1778-3585">1778-3585</a>)</span>: <span class="journal-volume">64</span> <span class="journal-issue">1</span> <span class="page"> Paper e21. 15 p. </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1192/j.eurpsy.2021.13" target="_blank" href="https://doi.org/10.1192/j.eurpsy.2021.13"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000631077700001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000631077700001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85103306064" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85103306064"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33726883" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33726883&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Psychiatry and Mental Health&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 158</span> | Független: 113 | Függő: 45 | Nem jelölt: 0 | WoS jelölt: 148 | Scopus jelölt:&nbsp;130 | WoS/Scopus jelölt:&nbsp;158 | DOI jelölt:&nbsp;156 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31952296&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 4 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 31952296</span> | <span class="status-data status-APPROVED"> Nyilvános </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Utolsó módosítás: 2023.01.17. 09:04 Csajbók Edit (SE_KK_Admin5_CSE, admin) </div> </div></div>