{ "labelLang" : "hun", "responseDate" : "2024-03-28 23:54", "content" : { "otype" : "JournalArticle", "mtid" : 31922615, "status" : "VALIDATED", "published" : true, "comment" : "Cited By :5 \n Export Date: 25 August 2021 \n CODEN: EMMEF \n Correspondence Address: Choi, T.-Y.; Department of Pathology, South Korea; email: choity76@wku.ac.kr \n Correspondence Address: Choe, S.-K.; Department of Biomedical Science, South Korea; email: seongkyu642@wku.ac.kr \n Correspondence Address: Kim, C.-H.; Department of Biology, South Korea; email: zebrakim@cnu.ac.kr", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2022-07-30T12:05:44.176+0000", "lastModified" : "2021-12-17T11:43:53.543+0000", "created" : "2021-03-19T10:02:24.824+0000", "creator" : { "otype" : "Admin", "mtid" : 10071503, "link" : "/api/admin/10071503", "label" : "Szabó Regina (ELTE TTK admin 5)", "familyName" : "Szabó", "givenName" : "Regina", "published" : true, "snippet" : true }, "lastDuplumOK" : "2022-03-08T10:32:04.833+0000", "lastDuplumSearch" : "2022-03-08T10:32:04.833+0000", "validated" : "2021-12-17T11:43:53.549+0000", "validator" : { "otype" : "Admin", "mtid" : 10025544, "link" : "/api/admin/10025544", "label" : "Lévayné Deseő Katalin (MTMT Központi admin)", "familyName" : "Lévayné Deseő", "givenName" : "Katalin", "published" : true, "oldId" : 10025544, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Szakcikk (Folyóiratcikk)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Choi, Tae-Young", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 95740750, "link" : "/api/authorship/95740750", "label" : "Choi, Tae-Young", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "corresponding" : false, "familyName" : "Choi", "givenName" : "Tae-Young", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 95740751, "link" : "/api/authorship/95740751", "label" : "Choi, Tae-Ik", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Choi", "givenName" : "Tae-Ik", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 95740752, "link" : "/api/authorship/95740752", "label" : "Lee, Yu-Ri", "listPosition" : 3, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Lee", "givenName" : "Yu-Ri", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 95740753, "link" : "/api/authorship/95740753", "label" : "Choe, Seong-Kyu", "listPosition" : 4, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Choe", "givenName" : "Seong-Kyu", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 95740754, "link" : "/api/authorship/95740754", "label" : "Kim, Cheol-Hee", "listPosition" : 5, "share" : 0.0, "first" : false, "last" : true, "corresponding" : false, "familyName" : "Kim", "givenName" : "Cheol-Hee", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "Zebrafish as an animal model for biomedical research", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 18544886, "link" : "/api/publicationidentifier/18544886", "label" : "DOI: 10.1038/s12276-021-00571-5", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1038/s12276-021-00571-5", "realUrl" : "https://doi.org/10.1038%2Fs12276-021-00571-5", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 18544888, "link" : "/api/publicationidentifier/18544888", "label" : "WoS: 000623811000001", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=@@@&DestApp=WOS", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000623811000001", "realUrl" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=000623811000001&DestApp=WOS", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 19160097, "link" : "/api/publicationidentifier/19160097", "label" : "Scopus: 85101854196", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85101854196", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85101854196", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 18544887, "link" : "/api/publicationidentifier/18544887", "label" : "PubMed: 33649498", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "idValue" : "33649498", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33649498&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 17301, "link" : "/api/journal/17301", "label" : "EXPERIMENTAL AND MOLECULAR MEDICINE 1226-3613 2092-6413", "pIssn" : "1226-3613", "eIssn" : "2092-6413", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 17301, "snippet" : true }, "volume" : "53", "issue" : "3", "firstPage" : "310", "lastPage" : "317", "firstPageOrInternalIdForSort" : "310", "pageLength" : 8, "publishedYear" : 2021, "abstractText" : "Zebrafish have several advantages compared to other vertebrate models used in modeling human diseases, particularly for large-scale genetic mutant and therapeutic compound screenings, and other biomedical research applications. With the impactful developments of CRISPR and next-generation sequencing technology, disease modeling in zebrafish is accelerating the understanding of the molecular mechanisms of human genetic diseases. These efforts are fundamental for the future of precision medicine because they provide new diagnostic and therapeutic solutions. This review focuses on zebrafish disease models for biomedical research, mainly in developmental disorders, mental disorders, and metabolic diseases. Animal models: Zebrafish help unlock clues to human disease With their see-through bodies, low maintenance costs and genetic similarity to humans, zebrafish provide a powerful animal model for studying mental disorders and metabolic diseases in the laboratory. Tae-Young Choi from Wonkwang University, Iksan, South Korea, and coworkers review the many physiological advantages and logistical benefits of rearing these small tropical fish for biomedical research. These include the ease of tissue imaging, the large number of offspring in each generation and the increasing number of genetic techniques available. The researchers highlight the various ways in which zebrafish have contributed to scientists' understanding of mental disorders and the communication pathways between brain and other organs in the body. They also discuss the potential of zebrafish for tracking metabolism and how it can go awry in various disease settings.", "digital" : null, "printed" : null, "sourceYear" : 2021, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "GOLD", "oaCheckDate" : "2022-07-30", "oaFree" : false, "oaLink" : "http://www.nature.com/emm/index.html", "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 1, "citedCount" : 1, "ratings" : [ { "otype" : "SjrRating", "mtid" : 11196102, "link" : "/api/sjrrating/11196102", "label" : "sjr:D1 (2021) Scopus - Biochemistry EXPERIMENTAL AND MOLECULAR MEDICINE 1226-3613 2092-6413", "listPos" : 26, "rankValue" : 0.1, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 1303, "link" : "/api/classificationexternal/1303", "label" : "Scopus - Biochemistry", "published" : true, "oldId" : 1303, "snippet" : true }, "ranking" : "D1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "D1", "hasCitationDuplums" : false, "userChangeableUntil" : "2021-06-17T09:09:09.387+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 7, "ownerInstituteCount" : 17, "directInstituteCount" : 0, "authorCount" : 5, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/31922615", "label" : "Choi Tae-Young et al. Zebrafish as an animal model for biomedical research. (2021) EXPERIMENTAL AND MOLECULAR MEDICINE 1226-3613 2092-6413 53 3 310-317", "template" : "