https://m2.mtmt.hu/ hun 2026-10-24 10:52 JournalArticle 31921210 VALIDATED true A3: Pócza, Tamás; 0 false 2026-09-03T07:37:53.068+0000 2023-01-06T09:45:54.395+0000 2021-03-18T13:07:50.396+0000 true 10070075 Nádas Orsolya /api/admin/10070075 Admin true 2023-02-06T13:02:11.840+0000 2023-02-06T13:02:11.840+0000 2021-05-14T07:43:30.018+0000 true 10070075 Nádas Orsolya /api/admin/10070075 Admin true 2021-05-27T09:34:16.394+0000 true 10015544 Csajbók Edit /api/admin/10015544 Admin true 10015544 Admin 10067876 /api/admin/10067876 Ladányi Gusztáv true true Admin 10080105 /api/admin/10080105 Kériné Tornyi Katalin true true 2024-10-17T16:16:12.275+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Farkas, Gyöngyi Biológiai dózisbecslés a sugárterápiában alkalmazott különböző sugárminőségű fotonnyaláboknál Biological dose estimation for photons of different qualities in radiation therapy true false /api/journal/1131031 REVIEWED true true 1131031 true 1131031 true 0025-0244 2060-0399 Journal HUNGARIAN 65 1 30 37 30 8 2021 Flattening filter free mode (FFF) has been introduced in radiotherapy during the past decades, however, not much has been reported on its radiobiological effect. The purpose of our study was to compare the radiobiological effects of flattening filter and flattening filter free photon beams on chromosomal aberrations in peripheral blood lymphocytes. In our study the blood of the same healthy donor was irradiated with linear accelerator using both conventional flattening filter (FF) and FFF photon beams at dose rate of 3.57-23.08 Gy/min, using 6 or 10 MV. The dose-response calibration curves for dicentric + ring chromosomes induced by irradiation were fitted with linear-quadratic model. CABAS (Chromosomal Aberration Calculation Software) was used to prepare the curves. The coefficients and equations of the curves were calculated and compared with the results of other authors. We found significant differences in the number of aberrations at different irradiation parameters. Based on our results, FFF mode has a 10-20% higher biological effect than FF mode. These results can be used during radiotherapy or to estimate the biological doses in case of an accidental exposure to radiation. 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<span class="author-name" mtid="10032265"><a href="/gui2/?type=authors&mode=browse&sel=10032265" target="_blank">Székely Gábor (<span class="authorship-author-name">Székely Gábor</span> <span class="authorAux-mtmt"> genetika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10042822"><a href="/gui2/?type=authors&mode=browse&sel=10042822" target="_blank">Pócza Tamás (<span class="authorship-author-name">Pócza Tamás</span> <span class="authorAux-mtmt"> Orvosi fizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10020433"><a href="/gui2/?type=authors&mode=browse&sel=10020433" target="_blank">Kocsis Zsuzsa S (<span class="authorship-author-name">Kocsis Zsuzsa</span> <span class="authorAux-mtmt"> sugárbiológia, onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10065843"><a href="/gui2/?type=authors&mode=browse&sel=10065843" target="_blank">Mihály Dalma (<span class="authorship-author-name">Mihály Dalma</span> <span class="authorAux-mtmt"> Klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10071423"><a href="/gui2/?type=authors&mode=browse&sel=10071423" target="_blank">Kun-Gazda Márta (<span class="authorship-author-name">Kun-Gazda Márta</span> <span class="authorAux-mtmt"> biológus</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10018107"><a href="/gui2/?type=authors&mode=browse&sel=10018107" target="_blank">Pesznyák Csilla (<span class="authorship-author-name">Pesznyák Csilla</span> <span class="authorAux-mtmt"> Orvosfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10044386"><a href="/gui2/?type=authors&mode=browse&sel=10044386" target="_blank">Major Tibor (<span class="authorship-author-name">Major Tibor</span> <span class="authorAux-mtmt"> klinikai sugárfizika</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10013383"><a href="/gui2/?type=authors&mode=browse&sel=10013383" target="_blank">Polgár Csaba (<span class="authorship-author-name">Polgár Csaba</span> <span class="authorAux-mtmt"> Sugárterápia, klinikai onkológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet; <span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Onkológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10010426"><a href="/gui2/?type=authors&mode=browse&sel=10010426" target="_blank">Jurányi Zsolt (<span class="authorship-author-name">Jurányi Zsolt</span> <span class="authorAux-mtmt"> Onkológiai kutatás, sugárterápia, sugárbiológia</span>) </a> </span> <span class="author-affil">Országos Onkológiai Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31921210" target="_blank">Biológiai dózisbecslés a sugárterápiában alkalmazott különböző sugárminőségű fotonnyaláboknál</a></div> <div> <span class="journal-title">MAGYAR ONKOLÓGIA</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/0025-0244">0025-0244</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2060-0399">2060-0399</a>)</span>: <span class="journal-volume">65</span> <span class="journal-issue">1</span> <span class="page"> pp 30-37 </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Magyar | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85103146169" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85103146169"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="33730114" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=33730114&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="http://huon.hu/2021/65/1/0030/0030a.pdf" target="_blank" href="http://huon.hu/2021/65/1/0030/0030a.pdf"> Teljes dokumentum </a> </span> <span class="id identifier oa_NONE" title=" Nincs "> <a style="color:blue" title="2021/65/1/0030/0030a.pdf" target="_blank" href="2021/65/1/0030/0030a.pdf"> Egyéb URL </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q4</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Oncology&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q4</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 1</span> | Független: 1 | Függő: 0 | Nem jelölt: 0 | WoS jelölt: 1 | Scopus jelölt:&nbsp;1 | WoS/Scopus jelölt:&nbsp;1 | DOI jelölt:&nbsp;1 </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 31921210</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">kézi felvitel</span> </div> <div class="funder"> (TKP2020_NKA-26) </div> <div class="lastModified">Utolsó módosítás: 2023.01.06. 10:45 Szalóky-Siki Ágnes (SE_KK_Admin5_SZSA, admin) </div> <div class="lockedBy">Központi kezelésű 2024.10.17. 18:16 Ladányi Gusztáv (MTMT API user, admin) Kériné Tornyi Katalin (MTMT ellenőrzés admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: A3: Pócza, Tamás;</pre> </div></div>