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"otype" : "Journal", "mtid" : 1129, "link" : "/api/journal/1129", "label" : "COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES 0147-9571 1878-1667", "pIssn" : "0147-9571", "eIssn" : "1878-1667", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 1129, "snippet" : true }, "volume" : "47", "firstPage" : "52", "lastPage" : "59", "firstPageOrInternalIdForSort" : "52", "pageLength" : 8, "publishedYear" : 2016, "abstractText" : "The efforts made to develop vaccines against Streptococcus suis have failed because of lack of common antigens cross-reactive against different serotypes of this species. The cell wall-anchored proteins can be good vaccine candidates due to their high expression and accessibility to antibodies, among these, a cell-wall protein, DNA-nuclease (SsnA), present in most of the S. suis serotypes and clinical isolates collected from infected pigs, was selected. An experimental challenge against S. suis serotype 2 in a pig model was used to validate the efficacy of recombinant SsnA combined with aluminium hydroxide plus Quil A as adjuvants, previously tested in mice by our research group with good results. In our study, clinical characteristics, bacterial load and spread, haematological and immunological parameters and the antibody response, including the opsonophagocytosis analysis of the sera were evaluated. Moreover the composition of peripheral blood leukocyte populations was studied in infected animals. The results show that the immunization of piglets with rSsnA elicits a significant humoral antibody response. However, the antibody response is not reflected in protection of pigs that are challenged with a virulent strain in our conventional vaccination model. Further studies are necessary to evaluate the use of rSsnA as a vaccine candidate for swine. (C) 2016 Elsevier Ltd. 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Crawley, A: Porcine Ig isotypes: function and molecular characteristics;", "listPosition" : 1, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731903, "link" : "/api/reference/18731903", "label" : "2. Summerfield, A: Depletion of CD4(+) and CD8(high+) T-cells before the onset of viraemia during classical swine fever;", "listPosition" : 2, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731904, "link" : "/api/reference/18731904", "label" : "3. Cordwell, SJ: Technologies for bacterial surface proteomics;", "listPosition" : 3, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731905, "link" : "/api/reference/18731905", "label" : "4. Dekker, C. N. T.: Homologous whole bacterin vaccination is not able to reduce Streptococcus suis serotype 9 strain 7997 transmission among pigs or colonization;", "listPosition" : 4, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731906, "link" : "/api/reference/18731906", "label" : "5. Hill, JE: Biochemical analysis, cpn60 and 16S rDNA sequence data indicate that Streptococcus suis serotypes 32 and 34, isolated from pigs, are Streptococcus orisratti;", "listPosition" : 5, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731907, "link" : "/api/reference/18731907", "label" : "6. Zhou, Yang: Evaluation of the protective efficacy of four novel identified membrane associated proteins of Streptococcus suis serotype 2;", "listPosition" : 6, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731908, "link" : "/api/reference/18731908", "label" : "7. Dominguez-Punaro, Maria C.: Streptococcus suis serotype 2, an important swine and human pathogen, induces strong systemic and cerebral inflammatory responses in a mouse model of infection;", "listPosition" : 7, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731909, "link" : "/api/reference/18731909", "label" : "8. Li, Yuanyi: Immunization with recombinant Sao protein confers protection against Streptococcus suis infection;", "listPosition" : 8, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731910, "link" : "/api/reference/18731910", "label" : "9. Goyette-Desjardins, Guillaume: Streptococcus suis, an important pig pathogen and emerging zoonotic agent-an update on the worldwide distribution based on serotyping and sequence typing;", "listPosition" : 9, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731911, "link" : "/api/reference/18731911", "label" : "10. Aranda, Jesus: Analysis of the protective capacity of three Streptococcus suis proteins induced under divalent-cation-limited conditions;", "listPosition" : 10, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731912, "link" : "/api/reference/18731912", "label" : "11. Beineke, Andreas: Comparative evaluation of virulence and pathology of Streptococcus suis serotypes 2 and 9 in experimentally infected growers;", "listPosition" : 11, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731913, "link" : "/api/reference/18731913", "label" : "12. Zlatkovic, Juergen: Aluminum Hydroxide Influences Not Only the Extent but Also the Fine Specificity and Functional Activity of Antibody Responses to Tick-Borne Encephalitis Virus in Mice;", "listPosition" : 12, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731914, "link" : "/api/reference/18731914", "label" : "13. Hsueh, K. -J.: Evaluation on a Streptococcus suis Vaccine Using Recombinant Sao-L Protein Manufactured by Bioreactors as the Antigen in Pigs;", "listPosition" : 13, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731915, "link" : "/api/reference/18731915", "label" : "14. de Buhr, Nicole: Streptococcus suis DNase SsnA contributes to degradation of neutrophil extracellular traps (NETs) and evasion of NET-mediated antimicrobial activity;", "listPosition" : 14, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731916, "link" : "/api/reference/18731916", "label" : "15. Gomez-Gascon, Lidia: Exploring the pan-surfome of Streptococcus suis: Looking for common protein antigens;", "listPosition" : 15, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731917, "link" : "/api/reference/18731917", "label" : "16. Vu Thi Lan Huong: Raw Pig Blood Consumption and Potential Risk for Streptococcus suis Infection, Vietnam;", "listPosition" : 16, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731918, "link" : "/api/reference/18731918", "label" : "17. Navarre, WW: Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope;", "listPosition" : 17, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731919, "link" : "/api/reference/18731919", "label" : "18. ALONSODEVELASCO, E: ADJUVANT QUIL-A IMPROVES PROTECTION IN MICE AND ENHANCES OPSONIC CAPACITY OF ANTISERA INDUCED BY PNEUMOCOCCAL POLYSACCHARIDE CONJUGATE VACCINES;", "listPosition" : 18, "published" : false, "snippet" : true }, { "otype" : "Reference", "mtid" : 18731920, "link" : "/api/reference/18731920", "label" : "19. 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