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The emergence of the city is a sign of civilization representing a higher form of human society. The development of cities plays an important role in regional and national economies. This paper investigates factors influencing urban agglomeration from the perspective of economic and population agglomeration. The authors selected 285 prefecture-level cities in China as a research sample and used the System Generalized Method of Moments (GMM) for regression analysis. The results reveal an inverted U-shaped relationship between housing prices and urban economic agglomeration in mid-western and eastern cities. However, an inverted U-shaped relationship was observed between housing prices and population agglomeration in the eastern cities and a U-shaped relationship in the mid-western cities of China. The influence of housing prices on population agglomeration can be divided into two periods. When housing prices were low, the population flowed from the mid-western to the eastern cities. 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