https://m2.mtmt.hu/ hun 2026-09-22 05:47 JournalArticle 3167989 VALIDATED true 0 2018-07-02T22:20:40.000+0000 false 3167989 2026-09-05T14:02:04.495+0000 2024-05-08T13:57:43.924+0000 2017-01-17T11:12:01.000+0000 true 10002629 Hegyi Péter /api/author/10002629 Author true 10002629 2024-10-08T06:06:51.900+0000 2023-09-02T14:56:51.893+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin true 10039043 Admin 10073918 /api/admin/10073918 Kovács Marcell true true 2023-10-19T08:01:11.860+0000 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Rumbus, Z Fever Is Associated with Reduced, Hypothermia with Increased Mortality in Septic Patients: A Meta-Analysis of Clinical Trials true true /api/journal/10007440 REVIEWED true false 10007440 false 10007440 true 1932-6203 Journal FOREIGN 12 1 e0170152 e0170152 15 2017 BACKGROUND: Sepsis is usually accompanied by changes of body temperature (Tb), but whether fever and hypothermia predict mortality equally or differently is not fully clarified. We aimed to find an association between Tb and mortality in septic patients with meta-analysis of clinical trials. METHODS: We searched the PubMed, EMBASE, and Cochrane Controlled Trials Registry databases (from inception to February 2016). Human studies reporting Tb and mortality of patients with sepsis were included in the analyses. Average Tb with SEM and mortality rate of septic patient groups were extracted by two authors independently. RESULTS: Forty-two studies reported Tb and mortality ratios in septic patients (n = 10,834). Pearson correlation analysis revealed weak negative linear correlation (R2 = 0.2794) between Tb and mortality. With forest plot analysis, we found a 22.2% (CI, 19.2-25.5) mortality rate in septic patients with fever (Tb > 38.0 degrees C), which was higher, 31.2% (CI, 25.7-37.3), in normothermic patients, and it was the highest, 47.3% (CI, 38.9-55.7), in hypothermic patients (Tb < 36.0 degrees C). Meta-regression analysis showed strong negative linear correlation between Tb and mortality rate (regression coefficient: -0.4318; P < 0.001). Mean Tb of the patients was higher in the lowest mortality quartile than in the highest: 38.1 degrees C (CI, 37.9-38.4) vs 37.1 degrees C (CI, 36.7-37.4). CONCLUSIONS: Deep Tb shows negative correlation with the clinical outcome in sepsis. Fever predicts lower, while hypothermia higher mortality rates compared with normal Tb. 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Belgyógyászati Klinika (PTE / ÁOK); MTA-SZTE Lendület Gasztroenterológiai Multidisz... 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/api/institute/14100 0 false true false Regionális Tudományok Bizottsága Committee on Regional Studies true 14100 true true true B nemzetközi false true SjrRating 10967509 /api/sjrrating/10967509 31 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 1101 /api/classificationexternal/1101 true 1101 true Q1 DIRECT true true /api/publication/3167989 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10062975"><a href="/gui2/?type=authors&mode=browse&sel=10062975" target="_blank">Rumbus Z (<span class="authorship-author-name">Rumbus Zoltán</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10012036"><a href="/gui2/?type=authors&mode=browse&sel=10012036" target="_blank">Matics R (<span class="authorship-author-name">Mátics Róbert</span> <span class="authorAux-mtmt"> Molekuláris filogenezis</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10002629"><a href="/gui2/?type=authors&mode=browse&sel=10002629" target="_blank">Hegyi P (<span class="authorship-author-name">Hegyi Péter</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika; <span title="Szegedi Tudományegyetem">SZTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/<span title="I. sz. Belgyógyászati Klinika">I.BelK</span>/MTA-SZTE Lendület Gasztroenterológiai Multidiszciplináris Kutatócsoport; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Zsiboras C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016931"><a href="/gui2/?type=authors&mode=browse&sel=10016931" target="_blank">Szabo I (<span class="authorship-author-name">Szabó Imre</span> <span class="authorAux-mtmt"> Belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016491"><a href="/gui2/?type=authors&mode=browse&sel=10016491" target="_blank">Illes A (<span class="authorship-author-name">Illés Anita</span> <span class="authorAux-mtmt"> Belgyógyászat</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016935"><a href="/gui2/?type=authors&mode=browse&sel=10016935" target="_blank">Petervari E (<span class="authorship-author-name">Pétervári Erika</span> <span class="authorAux-mtmt"> Az energia-háztartás szabályozása és mediátor-h...</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016413"><a href="/gui2/?type=authors&mode=browse&sel=10016413" target="_blank">Balasko M (<span class="authorship-author-name">Balaskó Márta</span> <span class="authorAux-mtmt"> Az energia-háztartás szabályozásának életkor- é...</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10060349"><a href="/gui2/?type=authors&mode=browse&sel=10060349" target="_blank">Marta K (<span class="authorship-author-name">Márta Katalin</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040441"><a href="/gui2/?type=authors&mode=browse&sel=10040441" target="_blank">Miko A (<span class="authorship-author-name">Mikó Alexandra</span> <span class="authorAux-mtmt"> Gasztroenterológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10021111"><a href="/gui2/?type=authors&mode=browse&sel=10021111" target="_blank">Parniczky A (<span class="authorship-author-name">Párniczky Andrea</span> <span class="authorAux-mtmt"> Orvostudomány</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/I. sz. Belgyógyászati Klinika; <span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10040445"><a href="/gui2/?type=authors&mode=browse&sel=10040445" target="_blank">Tenk J (<span class="authorship-author-name">Tenk Judit</span> <span class="authorAux-mtmt"> Anyagcsere</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10037684"><a href="/gui2/?type=authors&mode=browse&sel=10037684" target="_blank">Rostas I (<span class="authorship-author-name">Rostás Ildikó</span> <span class="authorAux-mtmt"> Kórélettan, gerontológia</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016619"><a href="/gui2/?type=authors&mode=browse&sel=10016619" target="_blank">Solymar M (<span class="authorship-author-name">Varjú-Solymár Margit</span> <span class="authorAux-mtmt"> Hőszabályozás</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10016462"><a href="/gui2/?type=authors&mode=browse&sel=10016462" target="_blank">Garami A ✉ (<span class="authorship-author-name">Garami András</span> <span class="authorAux-mtmt"> Testhőmérséklet-szabályozás</span>) </a> </span> <span class="author-affil"><span title="Pécsi Tudományegyetem">PTE</span>/<span title="Általános Orvostudományi Kar">ÁOK</span>/Transzlációs Medicina Intézet</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3167989" target="_blank">Fever Is Associated with Reduced, Hypothermia with Increased Mortality in Septic Patients: A Meta-Analysis of Clinical Trials</a></div> <div> <span class="journal-title">PLOS ONE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/1932-6203">1932-6203</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">1</span> <span class="page"> Paper e0170152. 15 p. </span> <span class="year">(2017)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.1371/journal.pone.0170152" target="_blank" href="https://doi.org/10.1371/journal.pone.0170152"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000391949500136" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000391949500136"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85009387140" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85009387140"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="28081244" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=28081244&dopt=Abstract"> PubMed </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:black" title="PMC5230786" target="_blank" href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230786"> Pubmed Central </a> </span> <span class="id identifier oa_GREEN" title=" Green "> <a style="color:black" title="11771" target="_blank" href="http://publicatio.bibl.u-szeged.hu/11771"> SZTE Publicatio </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Agricultural and Biological Sciences (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q1</div> <div class="journal-subject">Pedagógiai Tudományos Bizottság II. FTO PedTB [1901-]&nbsp;&nbsp;&nbsp;A</div> <div class="journal-subject">Szociológiai Tudományos Bizottság IXGJO SZTB [1901-]&nbsp;&nbsp;&nbsp;A nemzetközi</div> <div class="journal-subject">Regionális Tudományok Bizottsága IXGJO RTB [1901-]&nbsp;&nbsp;&nbsp;B nemzetközi</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 163</span> | Független: 153 | Függő: 10 | Nem jelölt: 0 | WoS jelölt: 128 | Scopus jelölt:&nbsp;112 | WoS/Scopus jelölt:&nbsp;145 | DOI jelölt:&nbsp;144 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3167989&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 3 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 3167989</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> <span class="oldId">Régi azonosító: 3167989</span> | Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2024.05.08. 15:57 Mikola Katalin (MTMT 3, admin) </div> <div class="lockedBy">Központi kezelésű 2023.10.19. 10:01 Kovács Marcell (MTMT Közp., admin) </div> </div></div>