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Tushar Kumeria has support from the National Medical and Health Research Council of Australia (NHMRC) with an Early Career Fellowship (GNT1143296), Australian Research Council for Discovery Project (DP200102723), and from the University of New South Wales and Scientia Grant. Amirali Popat is funded by a Development Fellowship with the NHMRC (GNT1146627). Jason Roberts would like to acknowledge funding from the Australian National Health and Medical Research Council for a Centre of Research Excellence (APP1099452) and a Practitioner Fellowship (APP1117065). 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