Pseudomonas putidais a Gram-negative, rod-shaped bacterium that can be encountered
in diverse ecological habitats. This ubiquity is traced to its remarkably versatile
metabolism, adapted to withstand physicochemical stress, and the capacity to thrive
in harsh environments. Owing to these characteristics, there is a growing interest
in this microbe for industrial use, and the corresponding research has made rapid
progress in recent years. Hereby, strong drivers are the exploitation of cheap renewable
feedstocks and waste streams to produce value-added chemicals and the steady progress
in genetic strain engineering and systems biology understanding of this bacterium.
Here, we summarize the recent advances and prospects in genetic engineering, systems
and synthetic biology, and applications ofP. putidaas a cell factory.