{ "labelLang" : "hun", "responseDate" : "2024-03-28 12:07", "content" : { "otype" : "JournalArticle", "mtid" : 31405585, "status" : "VALIDATED", "published" : true, "comment" : "Funding Agency and Grant Number: National Natural Scientific Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81703518, 81973406]; Hunan Provincial Natural Scientific Foundation [2019JJ50849]; Scientific Research Project of Hunan Provincial Health and Family Planning Commission [B20180253]\n Funding text: This work was supported by grants of the National Natural Scientific Foundation of China (Nos. 81703518 and 81973406), the Hunan Provincial Natural Scientific Foundation (No. 2019JJ50849), and the Scientific Research Project of Hunan Provincial Health and Family Planning Commission (No. B20180253).\nExport Date: 3 November 2020\nCited By :3 \n Export Date: 17 January 2021\nDepartment of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, China \n Institute of Clinical Pharmacy, Central South University, Changsha, China \n Cited By :10 \n Export Date: 20 May 2021 \n Correspondence Address: Zhang, B.; Department of Pharmacy, China; email: 505995@csu.edu.cn \n Correspondence Address: Li, W.; Department of Pharmacy, China; email: liwq1204@csu.edu.cn \n Correspondence Address: Zhang, B.; Institute of Clinical Pharmacy, China; email: 505995@csu.edu.cn \n Correspondence Address: Li, W.; Institute of Clinical Pharmacy, China; email: liwq1204@csu.edu.cn \n Chemicals/CAS: arsenic trioxide, 1303-24-8, 1327-53-3, 13464-58-9, 15502-74-6; capecitabine, 154361-50-9; cisplatin, 15663-27-1, 26035-31-4, 96081-74-2; cyclophosphamide, 50-18-0; dasatinib, 302962-49-8, 863127-77-9; doxorubicin, 23214-92-8, 25316-40-9; fluorouracil, 51-21-8; imatinib, 152459-95-5, 220127-57-1; mitoxantrone, 65271-80-9, 70476-82-3; nilotinib, 641571-10-0; pioglitazone, 105355-27-9, 111025-46-8; ponatinib, 943319-70-8, 1114544-31-8; rosiglitazone, 122320-73-4, 155141-29-0; sorafenib, 284461-73-0; sunitinib, 341031-54-7, 557795-19-4; trastuzumab, 180288-69-1, 1446410-98-5; zidovudine, 30516-87-1 \n Funding details: 81703518, 81973406 \n Funding details: B20180253 \n Funding details: Scientific Research Foundation of Hunan Provincial Education Department, 2019JJ50849 \n Funding text 1: Funding. This work was supported by grants of the National Natural Scientific Foundation of China (Nos. 81703518 and 81973406), the Hunan Provincial Natural Scientific Foundation (No. 2019JJ50849), and the Scientific Research Project of Hunan Provincial Health and Family Planning Commission (No. B20180253).", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2022-02-12T15:25:14.365+0000", "lastModified" : "2020-08-18T11:41:06.254+0000", "created" : "2020-08-18T11:06:59.682+0000", "creator" : { "otype" : "Admin", "mtid" : 10071503, "link" : "/api/admin/10071503", "label" : "Szabó Regina (ELTE TTK admin 5)", "familyName" : "Szabó", "givenName" : "Regina", "published" : true, "snippet" : true }, "lastDuplumSearch" : "2023-10-26T09:58:28.665+0000", "validated" : "2020-08-26T02:04:12.220+0000", "validator" : { "otype" : "Admin", "mtid" : 565, "link" : "/api/admin/565", "label" : "WoS import (admin)", "familyName" : "WoS", "givenName" : "import", "published" : true, "snippet" : true }, "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 10000059, "link" : "/api/subtype/10000059", "label" : "Szakcikk (Folyóiratcikk)", "name" : "Szakcikk", "nameEng" : "Article", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 101, "published" : true, "oldId" : 10000059, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Ma, Wanjun", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 92314654, "link" : "/api/authorship/92314654", "label" : "Ma, Wanjun", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "corresponding" : false, "familyName" : "Ma", "givenName" : "Wanjun", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 92314655, "link" : "/api/authorship/92314655", "label" : "Wei, Shanshan", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Wei", "givenName" : "Shanshan", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 92314656, "link" : "/api/authorship/92314656", "label" : "Zhang, Bikui", "listPosition" : 3, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Zhang", "givenName" : "Bikui", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 92314657, "link" : "/api/authorship/92314657", "label" : "Li, Wenqun", "listPosition" : 4, "share" : 0.0, "first" : false, "last" : true, "corresponding" : false, "familyName" : "Li", "givenName" : "Wenqun", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "Molecular Mechanisms of Cardiomyocyte Death in Drug-Induced Cardiotoxicity", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 17122597, "link" : "/api/publicationidentifier/17122597", "label" : "DOI: 10.3389/fcell.2020.00434", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.3389/fcell.2020.00434", "realUrl" : "https://doi.org/10.3389%2Ffcell.2020.00434", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 17122599, "link" : "/api/publicationidentifier/17122599", "label" : "WoS: 000543190700001", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=@@@&DestApp=WOS", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000543190700001", "realUrl" : "http://gateway.isiknowledge.com/gateway/Gateway.cgi?&GWVersion=2&SrcAuth=CustomerName&SrcApp=CustomerName&DestLinkType=FullRecord&KeyUT=000543190700001&DestApp=WOS", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 17853042, "link" : "/api/publicationidentifier/17853042", "label" : "Scopus: 85086582044", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85086582044", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85086582044", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 17122598, "link" : "/api/publicationidentifier/17122598", "label" : "PubMed: 32582710", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "32582710", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=32582710&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10043977, "link" : "/api/journal/10043977", "label" : "FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X", "eIssn" : "2296-634X", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10043977, "snippet" : true }, "volume" : "8", "internalId" : "434", "firstPageOrInternalIdForSort" : "434", "publishedYear" : 2020, "abstractText" : "Homeostatic regulation of cardiomyocytes plays a crucial role in maintaining the normal physiological activity of cardiac tissue. Severe cardiotoxicity results in cardiac diseases including but not limited to arrhythmia, myocardial infarction and myocardial hypertrophy. Drug-induced cardiotoxicity limits or forbids further use of the implicated drugs. Such drugs that are currently available in the clinic include anti-tumor drugs (doxorubicin, cisplatin, trastuzumab, etc.), antidiabetic drugs (rosiglitazone and pioglitazone), and an antiviral drug (zidovudine). This review focused on cardiomyocyte death forms and related mechanisms underlying clinical drug-induced cardiotoxicity, including apoptosis, autophagy, necrosis, necroptosis, pryoptosis, and ferroptosis. The key proteins involved in cardiomyocyte death signaling were discussed and evaluated, aiming to provide a theoretical basis and target for the prevention and treatment of drug-induced cardiotoxicity in the clinical practice.", "digital" : null, "printed" : null, "sourceYear" : 2020, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2022-02-12", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 4, "citedCount" : 4, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10985282, "link" : "/api/sjrrating/10985282", "label" : "sjr:Q1 (2020) Scopus - Cell Biology FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X", "listPos" : 47, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 1307, "link" : "/api/classificationexternal/1307", "label" : "Scopus - Cell Biology", "published" : true, "oldId" : 1307, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "userChangeableUntil" : "2020-11-16T12:41:05.891+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 30, "ownerInstituteCount" : 99, "directInstituteCount" : 0, "authorCount" : 4, "contributorCount" : 0, "hasQualityFactor" : true, "link" : "/api/publication/31405585", "label" : "Ma Wanjun et al. Molecular Mechanisms of Cardiomyocyte Death in Drug-Induced Cardiotoxicity. (2020) FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 2296-634X 2296-634X 8", "template" : "