Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia

https://m2.mtmt.hu/ eng 2026-09-23 02:51 JournalArticle 31312636 VALIDATED true Funding Agency and Grant Number: German Research Foundation [DE 1361/14-1, 213705389]; EPSRC [EP/M011933/1] Funding Source: UKRI; British Heart Foundation [PG/16/95/32350] Funding Source: researchfish; Engineering and Physical Sciences Research Council [EP/M011933/1] Funding Source: researchfish Funding text: We thank the German Research Foundation's Heisenberg Program for enabling the first Quantitative Cardiac Imaging meeting and Consensus Statement on the quantitative assessment of myocardial ischaemia with a grant to M.D. (DE 1361/14-1, project number 213705389). We thank B. Herwig (Department of Radiology, Charite, Berlin, Germany) for editorial assistance and E. Klotz (Siemens Healthineers) for his lecture during the meeting, which influenced the discussion at the first Quantitative Cardiac Imaging meeting, although he was not involved in the decisions made in this Consensus Statement. 0 false 2026-07-30T11:56:06.615+0000 2022-05-23T08:45:55.085+0000 2020-05-14T07:06:52.228+0000 true 10039043 Milánkovics Róbert /api/admin/10039043 Admin Róbert Milánkovics (PTE ÁOK admin 4) true 10039043 2024-11-12T10:39:21.890+0000 2022-05-23T08:45:55.285+0000 true 10080205 Szalóky-Siki Ágnes /api/admin/10080205 Admin Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) true true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000359 Study Group true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000359 Sokszerzős vagy csoportos szerzőségű szakcikk SubType Study Group (Journal Article) 104 true 10000359 true 1 /api/category/1 Category Scientific true 1 Dewey, Marc Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia true true /api/journal/10011741 REVIEWED NATURE REVIEWS CARDIOLOGY 1759-5002 1759-5010 true false 10011741 false 10011741 true 1759-5002 1759-5010 Journal FOREIGN 17 7 427 450 427 24 2020 Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic heart disease. SPECT is most commonly used for clinical myocardial perfusion imaging, whereas PET is the clinical reference standard for the quantification of myocardial perfusion. MRI does not involve exposure to ionizing radiation, similar to echocardiography, which can be performed at the bedside. CT perfusion imaging is not frequently used but CT offers coronary angiography data, and invasive catheter-based methods can measure coronary flow and pressure. Technical improvements to the quantification of pathophysiological parameters of myocardial ischaemia can be achieved. Clinical consensus recommendations on the appropriateness of each technique were derived following a European quantitative cardiac imaging meeting and using a real-time Delphi process. SPECT using new detectors allows the quantification of myocardial blood flow and is now also suited to patients with a high BMI. PET is well suited to patients with multivessel disease to confirm or exclude balanced ischaemia. MRI allows the evaluation of patients with complex disease who would benefit from imaging of function and fibrosis in addition to perfusion. Echocardiography remains the preferred technique for assessing ischaemia in bedside situations, whereas CT has the greatest value for combined quantification of stenosis and characterization of atherosclerosis in relation to myocardial ischaemia. In patients with a high probability of needing invasive treatment, invasive coronary flow and pressure measurement is well suited to guide treatment decisions. In this Consensus Statement, we summarize the strengths and weaknesses as well as the future technological potential of each imaging modality. Cardiac imaging has a pivotal role in the prevention, diagnosis and treatment of ischaemic heart disease. In this Consensus Statement, the authors summarize the use of SPECT, PET, MRI, echocardiography, CT and invasive coronary flow and pressure measurement, and describe the relative strengths and weaknesses of each modality. true 2020 true true true false true false NONE 2026-07-30 false 164 0 164 143 3 162 162 153 140 164 164 143 143 143 21 0 164 143 164 143 0 6 6 Folyóiratcikk Journal Article 24 154 Könyvrészlet Chapter in Book 25 10 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2020 0 8 8 8 8 2021 0 17 15 17 15 2022 0 32 28 32 28 2023 0 32 25 32 25 2024 0 28 22 28 22 2025 0 32 31 32 31 2026 0 15 14 15 14 D1 false false false false 2020-05-13T07:23:24.431+0000 MTA-SE Lendület Kardiovaszkuláris Képalkotó Kut... 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Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia. (2020) NATURE REVIEWS CARDIOLOGY 1759-5002 1759-5010 17 7 427-450<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Dewey Marc ✉ </span> ;    <span class="author-name" >Siebes Maria </span> ;    <span class="author-name" >Kachelriess Marc </span> ;    <span class="author-name" >Kofoed Klaus F. </span> ;    <span class="author-name" mtid="10019530"><a href="/gui2/?type=authors&mode=browse&sel=10019530" target="_blank">Maurovich-Horvat Pal (<span class="authorship-author-name">Maurovich-Horvat Pál</span> <span class="authorAux-mtmt"> kardiológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/<span title="Orvosi Képalkotó Klinika">OKK</span>/MTA-SE Cardiovascular Imaging Research Group</span> ;    <span class="author-name" >Nikolaou Konstantin </span> ;    <span class="author-name" >Bai Wenjia </span> ;    <span class="author-name" >Kofler Andreas </span> ;    <span class="author-name" >Manka Robert </span> ;    <span class="author-name" >Kozerke Sebastian </span> ;    <span class="author-name" >Chiribiri Amedeo </span> ;    <span class="author-name" >Schaeffter Tobias </span> ;    <span class="author-name" >Michallek Florian </span> ;    <span class="author-name" >Bengel Frank </span> ;    <span class="author-name" >Nekolla Stephan </span> ;    <span class="author-name" >Knaapen Paul </span> ;    <span class="author-name" >Lubberink Mark </span> ;    <span class="author-name" >Senior Roxy </span> ;    <span class="author-name" >Tang Meng-Xing </span> ;    <span class="author-name" >Piek Jan J. </span> ;    <span class="author-name" >van de Hoef Tim </span> ;    <span class="author-name" >Martens Johannes </span> ;    <span class="author-name" >Schreiber Laura </span> </div> <div class="autype autype-29"> Collaborative Organization: <span class="author-affil">Quantitative Cardiac Imaging Study</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31312636" target="_blank">Clinical quantitative cardiac imaging for the assessment of myocardial ischaemia</a></div> <div> <span class="journal-title">NATURE REVIEWS CARDIOLOGY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1759-5002">1759-5002</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1759-5010">1759-5010</a>)</span>: <span class="journal-volume">17</span> <span class="journal-issue">7</span> <span class="page"> pp 427-450 </span> <span class="year">(2020)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="10.1038/s41569-020-0341-8" target="_blank" href="https://doi.org/10.1038/s41569-020-0341-8"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000515474900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000515474900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85086606165" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85086606165"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="32094693" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=32094693&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Cardiology and Cardiovascular Medicine   Rank: D1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 164</span> | Independent citation: 143 | Self citation: 21 | Unknown citation: 0 | Number of citations in WoS: 153 | Number of citations in Scopus: 140 | WoS/Scopus assigned: 164 | Number of citations with DOI: 162 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31312636&sort=publishedYear,desc&sort=title"> Number of cited publications: 6 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 31312636</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Study Group ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">WOS TAGGED</span> </div> <div class="lastModified">Last Modified: 2022.05.23. 10:45 Ágnes Szalóky-Siki (SE_KK_Admin5_SZSA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Funding Agency and Grant Number: German Research Foundation [DE 1361/14-1, 213705389]; EPSRC [EP/M011933/1] Funding Source: UKRI; British Heart Foundation [PG/16/95/32350] Funding Source: researchfish; Engineering and Physical Sciences Research Council [EP/M011933/1] Funding Source: researchfish Funding text: We thank the German Research Foundation's Heisenberg Program for enabling ...</pre> </div></div>