https://m2.mtmt.hu/ eng 2026-04-21 12:05 JournalArticle 31293409 VALIDATED true Szövegében 3 oldalnál hosszabb esetismertetés, ezért besorolása szakcikk az MTA V. Osztályának ajánlása alapján. (BSzÁ, SZTE admin5, 2026-01-22) 0 false 2026-02-01T17:40:27.174+0000 2026-01-22T07:42:01.743+0000 2020-04-28T08:10:36.395+0000 true 10071337 Csajbók Edit /api/admin/10071337 Admin true 2026-01-22T07:41:49.286+0000 2026-01-22T07:41:49.286+0000 2026-01-22T07:42:01.912+0000 true 10083379 Belházyné Szombathelyi Ágnes /api/admin/10083379 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Molnar, Maria Judit Early-Onset Schizophrenia With Predominantly Negative Symptoms: A Case Study of a Drug-Naive Female Patient Treated With Cariprazine [case report] true true /api/journal/10026753 REVIEWED true false 10026753 false 10026753 true 1663-9812 Journal FOREIGN 11 477 477 6 2020 Schizophrenia is a chronic and severe mental disorder characterized by positive, negative, and cognitive symptoms. Negative symptoms are usually present from the prodromal phase; early diagnosis and management of negative symptoms is a major health concern since an insidious onset dominated by negative symptoms is associated with a worse outcome. Antipsychotic medications, which are effective for treating positive symptoms, are generally ineffective for treating negative or cognitive symptoms. We present a 23-year-old woman showing severe symptoms at her first visit to our department. The patient’s parents reported that their daughter had experienced several years of psychosocial decline and putative psychiatric symptoms, but no medical attention had been previously sought; as such, the diagnosis of schizophrenia with predominantly negative symptoms was very much delayed. Early onset of schizophrenia, longer duration of untreated psychosis, and severe negative symptoms, which have limited treatment options, suggested a poor prognosis. We initiated monotherapy with cariprazine, a novel antipsychotic that has recently been proven efficacious in treating schizophrenia with predominantly negative symptoms. This report describes a 52-week cariprazine treatment regimen and follows the patient’s impressive clinical improvement confirmed by PANSS and CGI scores, and psychological tests. true 2020 true true true false true false GOLD 2026-02-01 true https://doi.org/10.3389/fphar.2020.00477 12 0 12 10 0 12 12 12 12 12 12 10 10 10 2 0 12 10 12 10 0 1 1 Folyóiratcikk Journal Article 24 12 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2020 0 1 1 1 1 2021 0 0 0 0 0 2022 0 5 4 5 4 2023 0 1 1 1 1 2024 0 2 1 2 1 2025 0 3 3 3 3 Q1 false false false false 2020-04-27T08:18:49.555+0000 Genomikai Medicina és Ritka Betegségek Intézete (SE / AOK / I) 5 16 1 5 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 91514151 /api/authorship/91514151 1 0.2 true false true Author 10002781 /api/author/10002781 Molnár Mária Judit true 10002781 true Molnar Maria Judit true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 91514152 /api/authorship/91514152 2 0.2 false false false Author 10068012 /api/author/10068012 Jimoh Idris János true true Jimoh Idris János true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 91514153 /api/authorship/91514153 3 0.2 false false false Author 10052078 /api/author/10052078 Zeke Helga true 10052078 true Zeke Helga true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 91514154 /api/authorship/91514154 4 0.2 false false false Author 10067546 /api/author/10067546 Palásti Ágnes true true Palásti Ágnes true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PersonAuthorship 91514155 /api/authorship/91514155 5 0.2 false true false Author 10052143 /api/author/10052143 Fedor Mariann true 10052143 true Fedor Marianna true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false true PublicationIdentifier 16867810 /api/publicationidentifier/16867810 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.3389/fphar.2020.00477 https://doi.org/10.3389/fphar.2020.00477 false true PublicationIdentifier 16868109 /api/publicationidentifier/16868109 SwordSource 84 /api/publicationsource/84 PublicationSourceType 10007 /api/publicationsourcetype/10007 true true true SE Repozitórium SE Repozitórium https://repo.lib.semmelweis.hu/handle/123456789/@@@ true true 84 true GOLD true IDENTICAL 8257 https://repo.lib.semmelweis.hu/handle/123456789/8257 false true PublicationIdentifier 16946224 /api/publicationidentifier/16946224 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000532118900001 https://www.webofscience.com/wos/woscc/full-record/000532118900001 false true PublicationIdentifier 17850715 /api/publicationidentifier/17850715 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85084370393 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85084370393 false true PublicationIdentifier 16946222 /api/publicationidentifier/16946222 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 32390838 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=32390838&dopt=Abstract false true SjrRating 10873816 /api/sjrrating/10873816 37 0.24 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2736 /api/classificationexternal/2736 true 2736 true Q1 DIRECT true true /api/publication/31293409 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10002781"><a href="/gui2/?type=authors&mode=browse&sel=10002781" target="_blank">Molnar Maria Judit ✉ (<span class="authorship-author-name">Molnár Mária Judit</span> <span class="authorAux-mtmt"> Neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Genomic Medicine and the Institute of Rare Diseases</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10068012"><a href="/gui2/?type=authors&mode=browse&sel=10068012" target="_blank">Jimoh Idris János (<span class="authorship-author-name">Jimoh Idris János</span> <span class="authorAux-mtmt"> Neurogenetika</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Genomic Medicine and the Institute of Rare Diseases</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10052078"><a href="/gui2/?type=authors&mode=browse&sel=10052078" target="_blank">Zeke Helga (<span class="authorship-author-name">Zeke Helga</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Genomic Medicine and the Institute of Rare Diseases</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10067546"><a href="/gui2/?type=authors&mode=browse&sel=10067546" target="_blank">Palásti Ágnes (<span class="authorship-author-name">Palásti Ágnes</span> <span class="authorAux-mtmt"> neurológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Genomic Medicine and the Institute of Rare Diseases</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10052143"><a href="/gui2/?type=authors&mode=browse&sel=10052143" target="_blank">Fedor Marianna (<span class="authorship-author-name">Fedor Mariann</span> <span class="authorAux-mtmt"> klinikai pszichológia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Instituties">I</span>/Genomic Medicine and the Institute of Rare Diseases</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31293409" target="_blank">Early-Onset Schizophrenia With Predominantly Negative Symptoms: A Case Study of a Drug-Naive Female Patient Treated With Cariprazine : [case report].</a></div> <div> <span class="journal-title">FRONTIERS IN PHARMACOLOGY</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/1663-9812">1663-9812</a>)</span>: <span class="journal-volume">11</span> <span class="page"> Paper 477. 6 p. </span> <span class="year">(2020)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.3389/fphar.2020.00477" target="_blank" href="https://doi.org/10.3389/fphar.2020.00477"> DOI </a> </span> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="8257" target="_blank" href="https://repo.lib.semmelweis.hu/handle/123456789/8257"> SE Repozitórium </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000532118900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000532118900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85084370393" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85084370393"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="32390838" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=32390838&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Pharmacology (medical)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> <div class="journal-subject">Journal subject: Scopus - Pharmacology&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 12</span> | Independent citation: 10 | Self citation: 2 | Unknown citation: 0 | Number of citations in WoS: 12 | Number of citations in Scopus:&nbsp;12 | WoS/Scopus assigned:&nbsp;12 | Number of citations with DOI:&nbsp;12 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31293409&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 31293409</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">RIS-Egyéb</span> </div> <div class="lastModified">Last Modified: 2026.01.22. 08:42 Ágnes Belházyné Szombathelyi (SZTE admin5) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Szövegében 3 oldalnál hosszabb esetismertetés, ezért besorolása szakcikk az MTA V. Osztályának ajánlása alapján. (BSzÁ, SZTE admin5, 2026-01-22)</pre> </div></div>