Melanoma-associated fibroblasts impair CD8+ T cell function and modify expression of immune checkpoint regulators via increased arginase activity

Érsek, Barbara [Molnár-Érsek, Barbara (immunológia), author] Department of Genetics, Cell- and Immunology (SU / FM / I); Silló, Pálma* [Silló, Pálma (bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Ugur, Cakir [Cakir, Ugur (Bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Molnár, Viktor [Molnár, Viktor (tumor biológia), author] Genomic Medicine and the Institute of Rare Dise... (SU / FM / I); Bencsik, András [Bencsik, András (immunológia), author] Department of Genetics, Cell- and Immunology (SU / FM / I); Mayer, Balázs [Mayer, Balázs (bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Mezey, Eva; Kárpáti, Sarolta [Kárpáti, Sarolta (Bõrgyógyászat, ge...), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C); Pós, Zoltán** ✉ [Pós, Zoltán (Immunológia), author] Department of Genetics, Cell- and Immunology (SU / FM / I); Németh, Krisztián [Németh, Krisztián (Bőrgyógyászat), author] Department of Dermatology, Dermatooncology and ... (SU / FM / C)

Fundings:

• (Open access funding of Semmelweis University)
• (NN 114460) Funder: HSRF
• (116340) Funder: NKFIH
• Prémium Posztdoktori Kutatói ösztöndíj(PPD-003/2016) Funder: MTA
• (460011) Funder: MTA Premium
• SE ÁOK Dékán