Non-coding RNA molecules including microRNAs and long non-coding RNAs (lncRNA) have
been implicated in the pathogenesis of several tumors and numerous data support their
applicability in diagnosis as well. Despite recent advances, the pathogenesis of adrenocortical
cancer still remains elusive and there are no reliable blood-borne markers of adrenocortical
malignancy, either. Several findings show the potential applicability of microRNAs
as biomarkers of malignancy and prognosis, and there are some data on lncRNA as well.
In this review, we present a synopsis on the potential relevance of non-coding RNA
molecules in adrenocortical pathogenesis and their applicability in diagnosis from
tissue and blood.
