https://m2.mtmt.hu/ hun 2026-10-25 11:05 JournalArticle 31185081 VALIDATED true Cited By :14 Export Date: 8 January 2025 Correspondence Address: Merkely, G.; Cartilage Repair Center, United States; email: gmerkely@bwh.harvard.edu Correspondence Address: Merkely, G.; Department of Traumatology, Hungary; email: gmerkely@bwh.harvard.edu 0 false 2026-10-20T06:01:36.773+0000 2021-04-16T07:52:29.512+0000 2020-02-19T08:09:48.210+0000 true 10036572 Molnár Lajos /api/admin/10036572 Admin true 10036572 2025-03-24T08:34:12.586+0000 2021-04-16T07:52:29.525+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Merkely, G. Clinical Outcomes after Revision of Autologous Chondrocyte Implantation to Osteochondral Allograft Transplantation for Large Chondral Defects: A Comparative Matched-Group Analysis true true /api/journal/10020327 REVIEWED true false 10020327 false 10020327 true 1947-6035 1947-6043 Journal FOREIGN 12 2 155 161 155 7 2021 Objective: Osteochondral allograft transplantation (OCA) is a well-established procedure for patients with symptomatic cartilage defects in the knee. Revision to OCA after prior failed cartilage repair has shown similar clinical outcomes as primary OCA; however, most of the failed procedures were arthroscopic procedures for smaller defects. There is no literature investigating the clinical outcomes after OCA for prior failed autologous chondrocyte implantation (ACI) for the treatment of large chondral defects of the knee. The purpose of this study was therefore to determine clinical outcomes of patients undergoing revision to OCA after prior failed ACI as compared with a matched cohort of patients undergoing OCA as a primary cartilage repair procedure (primary OCA). Design: In this review of prospectively collected data, we analyzed data from 26 patients with at least 2 years follow-up. Thirteen patients who underwent revision to OCA after prior failed ACI by a single surgeon were compared with a matched group of patients who underwent primary OCA. The patients were matched per age, gender, body mass index, and defect size. Patient-reported outcomes, reoperations, and survival rates were compared between groups. Results: There were no significant differences in patient-reported clinical outcome scores between the groups at final follow-up. Moreover, there was no significant difference in reoperation rates and survival rates between the groups. Conclusion: The present study demonstrates that revision to OCA is a viable treatment option with favorable functional outcomes and similar reoperation and survival rate as primary OCA even for revision of large chondral defects previously treated with ACI. © The Author(s) 2019. true 2020 true true true false true false PAY 2026-10-20 false 17 0 17 13 0 16 17 13 16 17 17 13 13 13 4 0 17 13 17 13 0 1 1 Folyóiratcikk Journal Article 24 16 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2020 0 1 0 1 0 2021 0 5 4 5 4 2022 0 1 1 1 1 2023 0 4 4 4 4 2024 0 3 1 3 1 2025 0 3 3 3 3 Q2 Batty, L., Dance, S., Bajaj, S., Cole, B.J., Autologous chondrocyte implantation: an overview of technique and outcomes (2011) ANZ J Surg, 81 (1-2), pp. 18-25 ; Rosenberger, R.E., Gomoll, A.H., Bryant, T., Minas, T., Repair of large chondral defects of the knee with autologous chondrocyte implantation in patients 45 years or older (2008) Am J Sports Med, 36 (12), p. 2336. , (,):, -44 ; Farr, J., Cole, B., Dhawan, A., Kercher, J., Sherman, S., Clinical cartilage restoration: evolution and overview (2011) Clin Orthop Relat Res, 469 (10), p. 2696. , (,):, -705 ; Asik, M., Ciftci, F., Sen, C., Erdil, M., Atalar, A., The microfracture technique for the treatment of full-thickness articular cartilage lesions of the knee: midterm results (2008) Arthroscopy, 24 (11), p. 1214. , (,):, -20 ; Hangody, L., Dobos, J., Balo, E., Panics, G., Hangody, L.R., Berkes, I., Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: a 17-year prospective multicenter study (2010) Am J Sports Med, 38 (6), p. 1125. , (,):, -33 ; Minas, T., Von Keudell, A., Bryant, T., Gomoll, A.H., The John Insall Award: a minimum 10-year outcome study of autologous chondrocyte implantation (2014) Clin Orthop Relat Res, 472 (1), pp. 41-51 ; Nawaz, S.Z., Bentley, G., Briggs, T.W., Carrington, R.W., Skinner, J.A., Gallagher, K.R., Autologous chondrocyte implantation in the knee: mid-term to long-term results (2014) J Bone Joint Surg Am, 96 (10), p. 824. , (,):, -30 ; Ogura, T., Bryant, T., Minas, T., Long-term outcomes of autologous chondrocyte implantation in adolescent patients (2017) Am J Sports Med, 45 (5), p. 1066. , (,):, -74 ; Ogura, T., Mosier, B.A., Bryant, T., Minas, T., A 20-year follow-up after first-generation autologous chondrocyte implantation (2017) Am J Sports Med, 45 (12), p. 2751. , (,):, -61 ; Frank, R.M., Lee, S., Levy, D., Poland, S., Smith, M., Scalise, N., Osteochondral allograft transplantation of the knee: analysis of failures at 5 years (2017) Am J Sports Med, 45 (4), p. 864. , (,):, -74 ; Gomoll, A.H., Farr, J., Gillogly, S.D., Kercher, J.S., Minas, T., Surgical management of articular cartilage defects of the knee (2011) Instr Course Lect, 60, p. 461. , 83 ; Rosa, D., Di Donato, S.L., Balato, G., D’Addona, A., Smeraglia, F., Correra, G., How to manage a failed cartilage repair: a systematic literature review (2017) Joints, 5 (2), pp. 93-106 ; Minas, T., Gomoll, A.H., Rosenberger, R., Royce, R.O., Bryant, T., Increased failure rate of autologous chondrocyte implantation after previous treatment with marrow stimulation techniques (2009) Am J Sports Med, 37 (5), p. 902. , (,):, -8 ; Gracitelli, G.C., Meric, G., Pulido, P.A., McCauley, J.C., Bugbee, W.D., Osteochondral allograft transplantation for knee lesions after failure of cartilage repair surgery (2015) Cartilage, 6 (2), pp. 98-105 ; Murphy, R.T., Pennock, A.T., Bugbee, W.D., Osteochondral allograft transplantation of the knee in the pediatric and adolescent population (2014) Am J Sports Med, 42 (3), p. 635. , (,):, -40 ; Horton, M.T., Pulido, P.A., McCauley, J.C., Bugbee, W.D., Revision osteochondral allograft transplantations: do they work? 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SjrRating 11212773 /api/sjrrating/11212773 88 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2204 /api/classificationexternal/2204 true 2204 true Q2 DIRECT true true /api/publication/31185081 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10051885"><a href="/gui2/?type=authors&mode=browse&sel=10051885" target="_blank">Merkely G. ✉ (<span class="authorship-author-name">Merkely Gergő</span> <span class="authorAux-mtmt"> ortopédia</span>) </a> </span> <span class="author-affil"><span title="Semmelweis Egyetem">SE</span>/<span title="Általános Orvostudományi Kar">AOK</span>/<span title="Klinikum">K</span>/Traumatológiai Tanszék</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ogura T. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ackermann J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barbieri Mestriner A. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gomoll A.H. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31185081" target="_blank">Clinical Outcomes after Revision of Autologous Chondrocyte Implantation to Osteochondral Allograft Transplantation for Large Chondral Defects: A Comparative Matched-Group Analysis</a></div> <div> <span class="journal-title">CARTILAGE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6035">1947-6035</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6043">1947-6043</a>)</span>: <span class="journal-volume">12</span> <span class="journal-issue">2</span> <span class="page"> pp 155-161 </span> <span class="year">(2021)</span> </div> <div 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<OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Folyóirat szakterülete: Scopus - Biomedical Engineering&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Physical Therapy, Sports Therapy and Rehabilitation&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q2</div> <div class="journal-subject">Folyóirat szakterülete: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;SJR indikátor:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="Nyilvános idézőközlemények összesen, említések nélkül" class="citingPub-count">Nyilvános idéző összesen: 17</span> | Független: 13 | Függő: 4 | Nem jelölt: 0 | WoS jelölt: 13 | Scopus jelölt:&nbsp;16 | WoS/Scopus jelölt:&nbsp;17 | DOI jelölt:&nbsp;17 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31185081&sort=publishedYear,desc&sort=title"> Idézett közlemények száma: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Közlemény: 31185081</span> | <span class="status-data status-VALIDATED"> Egyeztetett </span> Forrás Idéző | <span class="type-subtype">Folyóiratcikk ( Szakcikk ) </span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Utolsó módosítás: 2021.04.16. 09:52 Molnár-Taga Márta (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Cited By :14 Export Date: 8 January 2025 Correspondence Address: Merkely, G.; Cartilage Repair Center, United States; email: gmerkely@bwh.harvard.edu Correspondence Address: Merkely, G.; Department of Traumatology, Hungary; email: gmerkely@bwh.harvard.edu</pre> </div></div>