https://m2.mtmt.hu/ eng 2026-10-23 18:49 JournalArticle 31185069 VALIDATED true Cartilage Repair Center, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States Department of Traumatology, Semmelweis University, Budapest, Hungary Sports Medicine Center, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States Balgrist University Hospital, Zurich, Switzerland Hospital for Special Surgery, New York, NY, United States Cited By :8 Export Date: 8 January 2025 Correspondence Address: Merkely, G.; Cartilage Repair Center, United States; email: gmerkely@bwh.harvard.edu 0 false 2026-10-20T06:01:42.081+0000 2022-02-02T13:59:18.195+0000 2020-02-19T08:09:13.700+0000 true 10036572 Molnár Lajos /api/admin/10036572 Admin Lajos Molnár (Uzsoki 4-es admin) true 10036572 2025-03-24T08:34:33.775+0000 2022-02-02T13:58:02.585+0000 true 10015546 Berhidi Anna /api/admin/10015546 Admin Anna Berhidi (SE_KK_Admin5_BA, admin) true 10015546 true false true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType Journal Article 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType Article (Journal Article) 101 true 10000059 true 1 /api/category/1 Category Scientific true 1 Merkely, G. true true /api/journal/10020327 REVIEWED CARTILAGE 1947-6035 1947-6043 true false 10020327 false 10020327 true 1947-6035 1947-6043 Journal FOREIGN 13 1_Suppl 1306S 1314S 1306S 9 2021 Objectives. The purpose of this study was to examine whether patients with diagnosed hypertension have an increased risk of graft failure following cartilage repair with either autologous chondrocyte implantation (ACI) or osteochondral allograft transplantation (OCA). We hypothesized that hypertension is related to higher ACI and OCA graft failure. Design. Patients who underwent ACI or OCA transplantation between February 2009 and December 2016 were included in this study. Inclusion criteria were (1) at least 2 years’ follow-up, (2) available information related to the living habits (smoking and medication status), and (3) available information related to the presence of hypertension, diabetes mellitus, or hyperlipidemia. To identify potential independent risk factors of graft failure, univariate screening was performed and factors with significance at a level of P < 0.1 were entered in multivariate logistic regression models. Results. A total of 368 patients (209 ACI and 159 OCA) were included into our study. In the ACI group, 61 patients’ (29.1%) graft failed. Univariate screening identified older age, female gender, defect size, higher prevalence of hypertension, and smoking as a predictor of graft failure. Following, multivariate logistic regression revealed female gender (odds ratio [OR] 1.02, P = 0.048), defect size (OR 1.07, P = 0.035), and hypertension (OR 3.73, P = 0.023) as significant independent risk factors predicting graft failure after ACI. In the OCA group, 29 patients’ (18.2%) graft failed and none of the included factors demonstrated to be a potential risk factor for graft failure. Conclusion. Hypertension, defect size, and female gender seem to predict ACI graft failure but not OCA failure. © The Author(s) 2020. 2020 true true true false true false PAY 2026-10-20 false 9 0 9 4 0 9 9 7 8 9 9 4 4 4 5 0 9 4 9 4 0 1 1 Folyóiratcikk Journal Article 24 8 Könyvrészlet Chapter in Book 25 1 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2020 0 2 0 2 0 2021 0 1 0 1 0 2022 0 2 0 2 0 2023 0 2 2 2 2 2024 0 1 1 1 1 2025 0 1 1 1 1 Q2 false 10051885 false false false 2020-05-19T07:12:23.741+0000 Traumatológiai Tanszék (SE / AOK / K); Uzsoki Utcai Kórház 1 13 2 3 0 true Language 10002 /api/language/10002 English Angol English true 2 true PersonAuthorship 90708785 /api/authorship/90708785 Merkely, G. ✉ [Merkely, Gergő (ortopédia), author] Budapest Uzsoki Street Hospital; Department of Traumatology (SU / FM / C) 1 0.33333334 true false true Author 10051885 /api/author/10051885 Gergő Merkely (ortopédia) Merkely Gergő true 10051885 true Merkely G. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 90708786 /api/authorship/90708786 Ackermann, J. 2 0.33333334 false false false Ackermann J. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PersonAuthorship 90708787 /api/authorship/90708787 Gomoll, A.H. 3 0.33333334 false true false Gomoll A.H. true false false AuthorshipType 1 /api/authorshiptype/1 Author 0 true 0 true false true PublicationIdentifier 16644185 /api/publicationidentifier/16644185 DOI: 10.1177/1947603519900792 PlainSource 6 /api/publicationsource/6 DOI PublicationSourceType 10001 /api/publicationsourcetype/10001 DOI true true true DOI DOI https://doi.org/@@@ true true 6 true PAY IDENTICAL 10.1177/1947603519900792 https://doi.org/10.1177/1947603519900792 false true PublicationIdentifier 16778652 /api/publicationidentifier/16778652 WoS: 000509069900001 PlainSource 1 /api/publicationsource/1 WoS PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000509069900001 https://www.webofscience.com/wos/woscc/full-record/000509069900001 false true PublicationIdentifier 16644184 /api/publicationidentifier/16644184 Scopus: 85078216504 PlainSource 3 /api/publicationsource/3 Scopus PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true IDENTICAL 85078216504 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85078216504 false true PublicationIdentifier 16778653 /api/publicationidentifier/16778653 PubMed: 31965812 PlainSource 17 /api/publicationsource/17 PubMed PublicationSourceType 10003 /api/publicationsourcetype/10003 Indexelő adatbázis false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true IDENTICAL 31965812 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31965812&dopt=Abstract false true Keyword 4807 /api/keyword/4807 HYPERTENSION true 4807 true Keyword 1526025 /api/keyword/1526025 cartilage repair true true Keyword 1657132 /api/keyword/1657132 Autologous chondrocyte implantation (ACI) true true Keyword 1970920 /api/keyword/1970920 osteochondral allograft transplantation (OCA) true true SjrRating 11212773 /api/sjrrating/11212773 sjr:Q2 (2021) Scopus - Biomedical Engineering CARTILAGE 1947-6035 88 0.49 journal RatingType 10002 /api/ratingtype/10002 sjr sjr true true ClassificationExternal 2204 /api/classificationexternal/2204 Scopus - Biomedical Engineering true 2204 true Q2 DIRECT true true Reference 2594996 /api/reference/2594996 1. 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(2021) CARTILAGE 1947-6035 1947-6043 13 1_Suppl 1306S-1314S<div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="10051885"><a href="/gui2/?type=authors&mode=browse&sel=10051885" target="_blank">Merkely G. ✉ (<span class="authorship-author-name">Merkely Gergő</span> <span class="authorAux-mtmt"> ortopédia</span>) </a> </span> <span class="author-affil">Budapest Uzsoki Street Hospital; <span title="Semmelweis University">SU</span>/<span title="Faculty of Medicine">FM</span>/<span title="Clinical">C</span>/Department of Traumatology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Ackermann J. </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Gomoll A.H. </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;31185069" target="_blank">The Role of Hypertension in Cartilage Restoration: Increased Failure Rate After Autologous Chondrocyte Implantation but Not After Osteochondral Allograft Transplantation</a></div> <div> <span class="journal-title">CARTILAGE</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6035">1947-6035</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/1947-6043">1947-6043</a>)</span>: <span class="journal-volume">13</span> <span class="journal-issue">1_Suppl</span> <span class="page"> pp 1306S-1314S </span> <span class="year">(2021)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Pay "> <a style="color:blue" title="10.1177/1947603519900792" target="_blank" href="https://doi.org/10.1177/1947603519900792"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000509069900001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000509069900001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="85078216504" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85078216504"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="31965812" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=31965812&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Biomedical Engineering&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Physical Therapy, Sports Therapy and Rehabilitation&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q2</div> <div class="journal-subject">Journal subject: Scopus - Immunology and Allergy&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q3</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 9</span> | Independent citation: 4 | Self citation: 5 | Unknown citation: 0 | Number of citations in WoS: 7 | Number of citations in Scopus:&nbsp;8 | WoS/Scopus assigned:&nbsp;9 | Number of citations with DOI:&nbsp;9 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;31185069&sort=publishedYear,desc&sort=title"> Number of cited publications: 1 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 31185069</span> | <span class="status-data status-VALIDATED"> Validated </span> Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">Scopus</span> </div> <div class="lastModified">Last Modified: 2022.02.02. 14:59 Anna Berhidi (SE_KK_Admin5_BA, admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Comments</u>: Cartilage Repair Center, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, United States Department of Traumatology, Semmelweis University, Budapest, Hungary Sports Medicine Center, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, United States Balgrist University Hospital, Zuri...</pre> </div></div>