Cloud-Based Multicenter Data Collection and Epidemiologic Analysis of Bisphosphonate-Related
Osteonecrosis of the Jaws in a Central European Population
Objective: Bisphosphonate-related osteonecrosis of the jaws is considered to be a
rare but severe complication of bisphosphonate therapy. To understand this condition
better, data collection is essential. Although the number of scientific papers about
this subject is large, to date only a few multicenter reports have been published.
Study design: We present a novel cloud-based data collection system for the evaluation
of the risk factors of bisphosphonate-related osteonecrosis of the jaws. Web-based
questionnaire and database have been set up and made available to voluntary researchers
and clinicians in oral and maxillofacial surgery in Hungary and Slovakia. Results:
To date, fifteen colleagues from eight maxillofacial units have joined the study.
Data of 180 patients have been recorded. Collected data were statistically analysed
and evaluated from an epidemiological point of view. Conclusions: Authors consider
cloud-based multicenter data collection a useful tool that allows for real-time collaboration
between users, facilitates fast data entry and analysis, and thus considerably contributes
to widening our knowledge of bisphosphonate-related osteonecrosis of the jaws.