https://m2.mtmt.hu/ eng 2026-10-25 06:05 JournalArticle 3117036 APPROVED true 0 2018-02-20T16:39:09.000+0000 false 3117036 2026-10-17T21:14:27.247+0000 2022-10-18T09:15:48.284+0000 2016-09-26T12:22:06.000+0000 true 210 Kerti-Szigeti Katalin /api/author/210 Author true 210 2025-03-17T15:26:18.281+0000 2025-04-10T10:11:59.595+0000 2019-02-22T10:03:44.543+0000 true 521 Szuper Admin /api/admin/521 Admin true true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 10000059 Article true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/10000059 Szakcikk SubType 101 true 10000059 true 1 /api/category/1 Category true 1 Kerti-Szigeti, K Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells. true true /api/journal/10031024 REVIEWED true false 10031024 false 10031024 true 2050-084X Journal FOREIGN 5 e18426 e18426 2016 Hippocampal pyramidal cells (PCs) express many GABAAR subunit types and receive GABAergic inputs from distinct interneurons. Previous experiments revealed input-specific differences in alpha1 and alpha2 subunit densities in perisomatic synapses, suggesting distinct IPSC decay kinetics. However, IPSC decays evoked by axo-axonic, parvalbumin- or cholecystokinin-expressing basket cells were found to be similar. Using replica immunogold labeling, here we show that all CA1 PC somatic and AIS synapses contain the alpha1, alpha2, beta1, beta2, beta3 and gamma2 subunits. In CA3 PCs, 90% of the perisomatic synapses are immunopositive for the alpha1 subunit and all synapses are positive for the remaining five subunits. Somatic synapses form unimodal distributions based on their immunoreactivity for these subunits. The alpha2 subunit densities in somatic synapses facing Cav2.1 (i.e. parvalbumin) or Cav2.2 (cholecystokinin) positive presynaptic active zones are comparable. We conclude that perisomatic synapses made by three distinct interneuron types have similar GABAA receptor subunit content. Funding 1992254 /api/funding/1992254 false true true true 2016 298359 true true true false true false GOLD 2026-10-17 true https://doi.org/10.7554/eLife.18426 true 10030885 Bálint Eszter /api/admin/10030885 Admin true 10030885 25 0 25 25 2 25 25 25 24 25 25 25 25 25 0 0 25 25 25 25 0 19 19 Folyóiratcikk Journal Article 24 25 Könyvrészlet Chapter in Book 25 0 Könyv Book 23 0 Egyéb konferenciaközlemény Conference paper 31 0 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 2017 0 6 6 6 6 2018 0 4 4 4 4 2019 0 3 3 3 3 2020 0 0 0 0 0 2021 0 3 3 3 3 2022 0 1 1 1 1 2023 0 3 3 3 3 2024 0 2 2 2 2 2025 0 2 2 2 2 2026 0 1 1 1 1 D1 false false false false 2016-12-25T13:23:33.000+0000 2016-09-26T12:23:33.000+0000 Celluláris Idegélettani Kutatócsoport (HRN KOKI) 2 10 1 2 0 true Language 10002 /api/language/10002 Angol English true 2 true PersonAuthorship 8266213 /api/authorship/8266213 1 0.5 true false Author 210 /api/author/210 Kerti-Szigeti Katalin true 210 true Kerti-Szigeti K true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24804518 true PersonAuthorship 8266214 /api/authorship/8266214 2 0.5 false true true Author 10000499 /api/author/10000499 Nusser Zoltán true 10000499 true Nusser Z true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24804517 true PublicationIdentifier 1129927 /api/publicationidentifier/1129927 PlainSource 6 /api/publicationsource/6 PublicationSourceType 10001 /api/publicationsourcetype/10001 true true true DOI DOI https://doi.org/@@@ true true 6 true GOLD true IDENTICAL 10.7554/eLife.18426 https://doi.org/10.7554/eLife.18426 false 1460033 true PublicationIdentifier 14769246 /api/publicationidentifier/14769246 PlainSource 1 /api/publicationsource/1 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true WoS WoS https://www.webofscience.com/wos/woscc/full-record/@@@ true true 1 true IDENTICAL 000383781000001 https://www.webofscience.com/wos/woscc/full-record/000383781000001 false 13788768 true PublicationIdentifier 1129926 /api/publicationidentifier/1129926 PlainSource 3 /api/publicationsource/3 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true Scopus Scopus http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@ true true 3 true false IDENTICAL 84983085018 http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84983085018 false 1725903 true PublicationIdentifier 1129929 /api/publicationidentifier/1129929 PlainSource 17 /api/publicationsource/17 PublicationSourceType 10003 /api/publicationsourcetype/10003 false true true PubMed PubMed http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract true true 17 true false IDENTICAL 27537197 http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=27537197&dopt=Abstract false 1460034 true Classification 12125 /api/classification/12125 true true Classification 10545 /api/classification/10545 true true Classification 12548 /api/classification/12548 true true Classification 12215 /api/classification/12215 true true SjrRating 10946621 /api/sjrrating/10946621 21 0.0 journal RatingType 10002 /api/ratingtype/10002 sjr true true ClassificationExternal 2701 /api/classificationexternal/2701 true 2701 true D1 DIRECT true true /api/publication/3117036 <div class="JournalArticle Publication long-list"> <div class="authors"> <img title="Forrásközlemény" style="float: left" src="/frontend/resources/grid/publication-core-icon.png"> <img title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" mtid="210"><a href="/gui2/?type=authors&mode=browse&sel=210" target="_blank">Kerti-Szigeti K (<span class="authorship-author-name">Kerti-Szigeti Katalin</span> <span class="authorAux-mtmt"> Celluláris idegélettan</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Cellular Neurophysiology</span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10000499"><a href="/gui2/?type=authors&mode=browse&sel=10000499" target="_blank">Nusser Z ✉ (<span class="authorship-author-name">Nusser Zoltán</span> <span class="authorAux-mtmt"> Celluláris idegélettan</span>) </a> </span> <span class="author-affil"><span title="MTA Kísérleti Orvostudományi Kutatóintézet">IEMHAS</span>/<span title="Department of Cellular and Network Neurobiology">DCNN</span>/Laboratory of Cellular Neurophysiology</span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3117036" target="_blank">Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells.</a></div> <div> <span class="journal-title">ELIFE</span> <span class="journal-issn">( <a target="_blank" href="https://portal.issn.org/resource/ISSN/2050-084X">2050-084X</a>)</span>: <span class="journal-volume">5</span> <span class="page"> Paper e18426. </span> <span class="year">(2016)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Language: English | </span> <span class="identifiers"> <span class="id identifier oa_GOLD" title=" Gold "> <a style="color:blue" title="10.7554/eLife.18426" target="_blank" href="https://doi.org/10.7554/eLife.18426"> DOI </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="000383781000001" target="_blank" href="https://www.webofscience.com/wos/woscc/full-record/000383781000001"> WoS </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="84983085018" target="_blank" href="http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-84983085018"> Scopus </a> </span> <span class="id identifier oa_none" title="none"> <a style="color:blue" title="27537197" target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=27537197&dopt=Abstract"> PubMed </a> </span> </span> <OnlyViewableByAuthor><div class="ratings"> <div class="journal-subject">Journal subject: Scopus - Biochemistry, Genetics and Molecular Biology (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Medicine (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Neuroscience (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;D1</div> <div class="journal-subject">Journal subject: Scopus - Immunology and Microbiology (miscellaneous)&nbsp;&nbsp;&nbsp;Rank:&nbsp;Q1</div> </div></OnlyViewableByAuthor> <div class="publication-citation" style="margin-left: 0.5cm;"> <span title="" class="citingPub-count">Citing papers: 25</span> | Independent citation: 25 | Self citation: 0 | Unknown citation: 0 | Number of citations in WoS: 25 | Number of citations in Scopus:&nbsp;24 | WoS/Scopus assigned:&nbsp;25 | Number of citations with DOI:&nbsp;25 </div> <div class="publication-citation"> <a target="_blank" href="/api/publication?cond=citations.related;eq;3117036&sort=publishedYear,desc&sort=title"> Number of cited publications: 19 </a> </div> <div class="mtid"><span class="long-pub-mtid">Publication: 3117036</span> | <span class="status-data status-APPROVED"> Published </span> <span class="oldId">Old id: 3117036</span> | Core Citing | <span class="type-subtype">Journal Article ( Article ) </span> | <span class="pub-category">Scientific</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="funder"> European Research Council Advanced Grant(293681) </div> <div class="lastModified">Last Modified: 2022.10.18. 11:15 Márta Turek (KOKI admin 4) </div> </div></div>