Asymptomatic atherosclerosis is a common entity even at young age. Studies have suggested
a strong relationship between increased arterial stiffness and asymptomatic carotid
atherosclerosis (ACA) in general population, particularly in those with high cardiovascular
risk, but no data exist from a younger population free from recognized cardiovascular
disease. Hypothesis. We hypothesized there is an association between ACA and aortic
pulse wave velocity (PWVao) in middle-aged, apparently healthy, normotensive population
to reveal increased cardiovascular risk.We examined the relationship between ACA and
PWVao in 236 apparently healthy, asymptomatic, normotensive, middle-aged subjects
(age 47 ± 8 years; 52% women). PWVao was measured with the oscillometric method (Arteriograph).
ACA was assessed by carotid artery ultrasonography.ACA was present in 51 subjects.
Subjects with ACA were older (p < 0.009), more likely to be smokers (p < 0.009), more
likely to be smokers (p < 0.009), more likely to be smokers (p < 0.009), more likely
to be smokers (p < 0.009), more likely to be smokers (p < 0.009), more likely to be
smokers (p < 0.009), more likely to be smokers (p < 0.009), more likely to be smokers
(.PWVao measured by the Arteriograph proved to be an independent marker of ACA. Our
study may reveal high CV risk, detected as increased PWVao, which according to our
study is related in a very high probability to asymptomatic carotid atherosclerosis
in apparently healthy, young, and middle-aged subjects.
