A szívinfarktusért felelős ér prognosztikus jelentőségének vizsgálata ST-elevációs szívinfarktusos betegekben

Jánosi, András [Jánosi, András (Kardiológia), author] Gottsegen György Országos Kardiológiai Intézet; Ofner, Péter; Simkovits, Dániel [Simkovits, Dániel (kardiológia), author] Gottsegen György Országos Kardiológiai Intézet; Ferenci, Tamás [Ferenci, Tamás (Biostatisztika), author] Biomatika Intézet (ÓU / NJFCS)

Hungarian Article (Journal Article) Scientific
Published: ORVOSI HETILAP 0030-6002 1788-6120 157 (32) pp. 1282-1288 2016
  • Pszichológiai Tudományos Bizottság: A
  • Demográfiai Osztályközi Állandó Bizottság: A hazai
  • SJR Scopus - Medicine (miscellaneous): Q4
Subjects:
  • Other medical sciences
  • Clinical medicine
Introduction: To the best of the authors' knowledge, very few publications are available which report on the prognostic significance of the culprit vessel in patients with ST elevation myocardial infarction treated with successful primary percutaneous coronary intervention. Aim: The aim of the authors was to obtain data on the significance of the culprit vessel in patients with ST elevation myocardial infarction treated successfully by primary percutaneous coronary intervention. Method: The authors performed a retrospective study in 10,763 patients with ST elevation myocardial infarction who underwent successful primary percutaneous coronary intervention. The culprit vessels were the left main artery, left anterior descendent artery, left circumflex artery, and right coronary artery. The authors constructed univariate survival curves for different culprit vessels and also performed multivariate modelling of time-to-death, controlling for age, sex, and comorbidities. Results: The majority of the culprit lesions were found in the left anterior descendent artery (44.3%), the right coronary artery (40.9%), and the left circumflex artery (13.7%). The culprit vessel was overall a highly significant (p<0.0001) factor of survival, with right coronary artery exhibiting a highly significantly better prognosis (hazard ratio 0.69, 95% CI 0.61-0.79, p<0.0001) and left main artery exhibiting a significantly worse prognosis (hazard ratio 1.56, 95% CI 1.04-2.35, p = 0.0321) than the reference vessel (left anterior descendent artery). Conclusion: These data demonstrate that the culprit vessel has independent prognostic significance.
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2024-02-21 08:44