{ "labelLang" : "hun", "responseDate" : "2024-03-28 21:52", "content" : { "otype" : "JournalArticle", "mtid" : 31074280, "status" : "APPROVED", "published" : true, "comment" : "Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom \n Department of Pharmacy Pharmacology, University of Bath, Bath, United Kingdom \n Systemic Immune-Mediated Diseases Unit, Department of Medicine IV, Fernando Fonseca Hospital, Amadora, Portugal \n Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy \n Internal Medicine and Rheumatology, Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania \n Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy \n Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy \n Scleroderma Program, Division of Rheumatology, University of Michigan, Ann Arbor, MI, United States \n Cited By :2 \n Export Date: 26 August 2021 \n Correspondence Address: Pauling, J.D.; Royal National Hospital for Rheumatic DiseasesUnited Kingdom; email: JohnPauling@nhs.net\nRoyal National Hospital for Rheumatic Diseases, Bath, United Kingdom \n Department of Pharmacy Pharmacology, University of Bath, Bath, United Kingdom \n Systemic Immune-Mediated Diseases Unit, Department of Medicine IV, Fernando Fonseca Hospital, Amadora, Portugal \n Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy \n Internal Medicine and Rheumatology, Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania \n Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Italy \n Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy \n Scleroderma Program, Division of Rheumatology, University of Michigan, Ann Arbor, MI, United States \n Cited By :2 \n Export Date: 31 August 2021 \n Correspondence Address: Pauling, J.D.; Royal National Hospital for Rheumatic DiseasesUnited Kingdom; email: JohnPauling@nhs.net", "unhandledTickets" : 0, "deleted" : false, "lastRefresh" : "2023-07-15T20:20:01.478+0000", "lastModified" : "2022-09-26T10:03:49.045+0000", "created" : "2020-01-09T18:41:43.578+0000", "creator" : { "otype" : "Admin", "mtid" : 565, "link" : "/api/admin/565", "label" : "WoS import (admin)", "familyName" : "WoS", "givenName" : "import", "published" : true, "snippet" : true }, "lastDuplumSearch" : "2023-02-08T21:04:33.876+0000", "core" : false, "citation" : true, "publicationPending" : false, "type" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "subType" : { "otype" : "SubType", "mtid" : 1134514, "link" : "/api/subtype/1134514", "label" : "Összefoglaló cikk (Folyóiratcikk)", "name" : "Összefoglaló cikk", "nameEng" : "Survey paper", "docType" : { "otype" : "PublicationType", "mtid" : 24, "link" : "/api/publicationtype/24", "label" : "Folyóiratcikk", "code" : 24, "otypeName" : "JournalArticle", "listPosition" : 1, "published" : true, "oldId" : 24, "snippet" : true }, "listPosition" : 102, "published" : true, "oldId" : 1134514, "snippet" : true }, "category" : { "otype" : "Category", "mtid" : 1, "link" : "/api/category/1", "label" : "Tudományos", "published" : true, "oldId" : 1, "snippet" : true }, "languages" : [ { "otype" : "Language", "mtid" : 10002, "link" : "/api/language/10002", "label" : "Angol", "name" : "Angol", "nameEng" : "English", "published" : true, "oldId" : 2, "snippet" : true } ], "firstAuthor" : "Pauling, John D.", "authorships" : [ { "otype" : "PersonAuthorship", "mtid" : 90023638, "link" : "/api/authorship/90023638", "label" : "Pauling, John D. ✉", "listPosition" : 1, "share" : 0.0, "first" : true, "last" : false, "corresponding" : true, "familyName" : "Pauling", "givenName" : "John D.", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023639, "link" : "/api/authorship/90023639", "label" : "Caetano, Joana", "listPosition" : 2, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Caetano", "givenName" : "Joana", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023640, "link" : "/api/authorship/90023640", "label" : "Campochiaro, Corrado", "listPosition" : 3, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Campochiaro", "givenName" : "Corrado", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023641, "link" : "/api/authorship/90023641", "label" : "De Luca, Giacomo", "listPosition" : 4, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "De Luca", "givenName" : "Giacomo", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023642, "link" : "/api/authorship/90023642", "label" : "Gheorghiu, Ana Maria", "listPosition" : 5, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Gheorghiu", "givenName" : "Ana Maria", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023643, "link" : "/api/authorship/90023643", "label" : "Lazzaroni, Maria Grazia", "listPosition" : 6, "share" : 0.0, "first" : false, "last" : false, "corresponding" : false, "familyName" : "Lazzaroni", "givenName" : "Maria Grazia", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true }, { "otype" : "PersonAuthorship", "mtid" : 90023644, "link" : "/api/authorship/90023644", "label" : "Khanna, Dinesh", "listPosition" : 7, "share" : 0.0, "first" : false, "last" : true, "corresponding" : false, "familyName" : "Khanna", "givenName" : "Dinesh", "authorTyped" : true, "editorTyped" : false, "otherTyped" : false, "type" : { "otype" : "AuthorshipType", "mtid" : 1, "link" : "/api/authorshiptype/1", "label" : "Szerző", "code" : 0, "published" : true, "oldId" : 0, "snippet" : true }, "published" : false, "snippet" : true } ], "title" : "Patient-reported outcome instruments in clinical trials of systemic sclerosis", "identifiers" : [ { "otype" : "PublicationIdentifier", "mtid" : 16420584, "link" : "/api/publicationidentifier/16420584", "label" : "DOI: 10.1177/2397198319886496", "source" : { "otype" : "PlainSource", "mtid" : 6, "link" : "/api/publicationsource/6", "label" : "DOI", "type" : { "otype" : "PublicationSourceType", "mtid" : 10001, "link" : "/api/publicationsourcetype/10001", "label" : "DOI", "mayHaveOa" : true, "published" : true, "snippet" : true }, "name" : "DOI", "nameEng" : "DOI", "linkPattern" : "https://doi.org/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 6, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "10.1177/2397198319886496", "realUrl" : "https://doi.org/10.1177/2397198319886496", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 16420583, "link" : "/api/publicationidentifier/16420583", "label" : "WoS: 000499298700001", "source" : { "otype" : "PlainSource", "mtid" : 1, "link" : "/api/publicationsource/1", "label" : "WoS", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "WoS", "nameEng" : "WoS", "linkPattern" : "https://www.webofscience.com/wos/woscc/full-record/@@@", "publiclyVisible" : true, "published" : true, "oldId" : 1, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "000499298700001", "realUrl" : "https://www.webofscience.com/wos/woscc/full-record/000499298700001", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 19162384, "link" : "/api/publicationidentifier/19162384", "label" : "Scopus: 85075571764", "source" : { "otype" : "PlainSource", "mtid" : 3, "link" : "/api/publicationsource/3", "label" : "Scopus", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "Scopus", "linkPattern" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-@@@", "publiclyVisible" : true, "published" : true, "oldId" : 3, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "85075571764", "realUrl" : "http://www.scopus.com/record/display.url?origin=inward&eid=2-s2.0-85075571764", "published" : false, "snippet" : true }, { "otype" : "PublicationIdentifier", "mtid" : 21596174, "link" : "/api/publicationidentifier/21596174", "label" : "PubMed: 35382020", "source" : { "otype" : "PlainSource", "mtid" : 17, "link" : "/api/publicationsource/17", "label" : "PubMed", "type" : { "otype" : "PublicationSourceType", "mtid" : 10003, "link" : "/api/publicationsourcetype/10003", "label" : "Indexelő adatbázis", "mayHaveOa" : false, "published" : true, "snippet" : true }, "name" : "PubMed", "nameEng" : "PubMed", "linkPattern" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=@@@&dopt=Abstract", "publiclyVisible" : true, "published" : true, "oldId" : 17, "snippet" : true }, "validState" : "IDENTICAL", "idValue" : "35382020", "realUrl" : "http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=35382020&dopt=Abstract", "published" : false, "snippet" : true } ], "journal" : { "otype" : "Journal", "mtid" : 10073702, "link" : "/api/journal/10073702", "label" : "JOURNAL OF SCLERODERMA AND RELATED DISORDERS 2397-1983 2397-1991", "pIssn" : "2397-1983", "eIssn" : "2397-1991", "reviewType" : "REVIEWED", "noIF" : false, "sciIndexed" : true, "scopusIndexed" : true, "lang" : "FOREIGN", "hungarian" : false, "published" : true, "oldId" : 10073702, "snippet" : true }, "volume" : "5", "issue" : "2", "firstPage" : "90", "lastPage" : "102", "firstPageOrInternalIdForSort" : "90", "pageLength" : 13, "publishedYear" : 2020, "abstractText" : "Patient-reported outcome instruments provide valuable insight into disease-related morbidity known only to the patient and complement more objective outcome tools in the clinical trial setting. They are of particular importance in systemic sclerosis owing to the challenges around defining disease activity, the episodic nature of many disease-specific manifestations and the paucity of validated objective surrogate outcome measures for use in clinical trials. Early clinical trials of systemic sclerosis often incorporated legacy patient-reported outcome instruments, but the last 20 years has witnessed the emergence of several scleroderma-specific instruments that are now being routinely used alongside other outcomes in systemic sclerosis clinical trials. More recently, the value of patient-reported outcomes has been highlighted by their prominence in the American College of Rheumatology Combined Response Index for Systemic Sclerosis that has been utilized as the primary endpoint of recent clinical trials of early diffuse systemic sclerosis. This review considers the role and performance of the various patient-reported outcome instruments utilized in systemic sclerosis clinical trials, the current positioning of patient-reported outcome instruments within clinical trial endpoint models across the range of systemic sclerosis disease manifestations and, where applicable, we shall highlight areas for future research.", "subjects" : [ { "otype" : "Classification", "mtid" : 12215, "link" : "/api/classification/12215", "label" : "Klinikai orvostan", "published" : true, "snippet" : true } ], "keywords" : [ { "otype" : "Keyword", "mtid" : 14471, "link" : "/api/keyword/14471", "label" : "Clinical Trials", "published" : true, "oldId" : 14471, "snippet" : true }, { "otype" : "Keyword", "mtid" : 20166, "link" : "/api/keyword/20166", "label" : "systemic sclerosis", "published" : true, "oldId" : 20166, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1186972, "link" : "/api/keyword/1186972", "label" : "outcome measures", "published" : true, "oldId" : 1186972, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1584169, "link" : "/api/keyword/1584169", "label" : "Raynaud's phenomenon", "published" : true, "snippet" : true }, { "otype" : "Keyword", "mtid" : 1906053, "link" : "/api/keyword/1906053", "label" : "Patient-reported outcome instruments", "published" : true, "snippet" : true } ], "digital" : null, "printed" : null, "sourceYear" : 2020, "foreignEdition" : true, "foreignLanguage" : true, "fullPublication" : true, "conferencePublication" : false, "nationalOrigin" : null, "missingAuthor" : false, "oaType" : "NONE", "oaCheckDate" : "2023-07-15", "oaFree" : false, "citationCount" : 0, "citationCountUnpublished" : 0, "citationCountWoOther" : 0, "independentCitCountWoOther" : 0, "doiCitationCount" : 0, "wosCitationCount" : 0, "scopusCitationCount" : 0, "independentCitationCount" : 0, "unhandledCitationCount" : 0, "citingPubCount" : 0, "independentCitingPubCount" : 0, "unhandledCitingPubCount" : 0, "citedPubCount" : 6, "citedCount" : 6, "ratings" : [ { "otype" : "SjrRating", "mtid" : 10821319, "link" : "/api/sjrrating/10821319", "label" : "sjr:Q1 (2020) Scopus - Immunology and Allergy JOURNAL OF SCLERODERMA AND RELATED DISORDERS 2397-1983 2397-1991", "listPos" : 45, "rankValue" : 0.24, "type" : "journal", "ratingType" : { "otype" : "RatingType", "mtid" : 10002, "link" : "/api/ratingtype/10002", "label" : "sjr", "code" : "sjr", "published" : true, "snippet" : true }, "subject" : { "otype" : "ClassificationExternal", "mtid" : 2723, "link" : "/api/classificationexternal/2723", "label" : "Scopus - Immunology and Allergy", "published" : true, "oldId" : 2723, "snippet" : true }, "ranking" : "Q1", "calculation" : "DIRECT", "published" : true, "snippet" : true } ], "ratingsForSort" : "Q1", "hasCitationDuplums" : false, "userChangeableUntil" : "2022-12-25T11:03:48.812+0000", "directInstitutesForSort" : "", "ownerAuthorCount" : 11, "ownerInstituteCount" : 30, "directInstituteCount" : 0, "authorCount" : 7, "contributorCount" : 0, "hasQualityFactor" : false, "link" : "/api/publication/31074280", "label" : "Pauling John D. et al. Patient-reported outcome instruments in clinical trials of systemic sclerosis. (2020) JOURNAL OF SCLERODERMA AND RELATED DISORDERS 2397-1983 2397-1991 5 2 90-102", "template" : "