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The University of Trnava had originally been established in 1635 but the Faculty of Medicine was added only later, in 1769, when the name of the university was also changed to Royal Hungarian University of Sciences. A fresh graduate, Vaclav Trnka from Krovice (1739-1791), was appointed as head of the Department of Anatomy. He was not only an anatomist, but a real polymath of the second half of the eighteenth century practicing medicine as well as becoming the Dean, then the Rector of the University. He has lived and acted within several countries of Central Europe, or rather, the Austrio-Hungarian monarchy during the reign of Empress Maria Theresia, then her son Joseph II. Born in Bohemia (now Czech Republic), studied and graduated in Austria, then finally was appointed as the first Professor of Anatomy of a newly established medical faculty in Upper Hungary (now Slovakia). In 1777, the university was moved first to Buda, then to Pest (now parts of the capital of Hungary), and the Faculty of Medicine was not separated from the rest of the faculties before the end of the Second World War. Following several institutional and name changes, this Medical Faculty is considered as the foundation of the present Semmelweis University. Trnka was a proliferous author, publishing more than 20 monographs covering various branches of clinical medicine, however, no anatomical work may be connected to his activity. 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