https://m2.mtmt.hu/ hun 2026-05-25 13:49 JournalArticle 3091887 VALIDATED true Geha Mental Health Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Division of Molecular Imaging and Neuropathology, Department of Psychiatry, Columbia University, New York, NY, United States Centre for Suicide Research, University of Oxford, Oxford, United Kingdom National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Karolinska Institute, Stockholm, Sweden Unit for Suicide Research, Ghent University, Ghent, Belgium National Suicide Research Foundation, Department of Epidemiology and Public Health, University College Cork, Cork, Ireland Department of Medicine and Health Science, University of Molise, Via De Santis Campobasso and National Institute for Health, Migration and Poverty, Roma, Italy National Institute of Mental Health, Klecany, Czech Republic Department of Developmental and Clinical Child Psychology, Institute of Psychology, Eotvos Lorand University, Budapest, Hungary Institute of Behavioral Sciences, Semmelweis University Budapest, Budapest, Hungary Université de Lorraine, Pôle de Psychiatrie et Psychologie Clinique, Centre Psychothérapique de Nancy-Laxou, Nancy-Laxou, France Department of Psychiatry, University of Oviedo, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM Oviedo, Spain Department of Community Mental Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel Department of Clinical Psychology, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania Department of Psychiatry and Psychotherapy, University of Leipzig, Leipzig, Germany Psychiatry Department, Sheba Health Center and Sackler School of Medicine, Tel Aviv University, Tel Avis, Israel Cited By :1216 Export Date: 5 March 2025 Correspondence Address: Zalsman, G.; Geha Mental Health Center and Psychiatry Department, Israel; email: zalsman@post.tau.ac.il 0 2016-12-02T12:35:07.000+0000 false 3091887 2026-05-17T10:45:29.750+0000 2019-11-12T11:16:57.239+0000 2016-06-10T11:54:20.000+0000 true 10011527 Balázs Judit /api/author/10011527 Author true 10011527 2025-03-05T10:54:16.988+0000 2016-11-24T12:31:39.000+0000 true 10028855 Klein László /api/admin/10028855 Admin true 10028855 2019-11-12T11:16:57.251+0000 true 10062250 Molnár-Taga Márta /api/admin/10062250 Admin true 10062250 true false true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle true 1134514 Survey paper true 24 24 /api/publicationtype/24 PublicationType 1 true 24 JournalArticle /api/subtype/1134514 Összefoglaló cikk SubType 102 true 1134514 true 1 /api/category/1 Category true 1 Zalsman, G Suicide prevention strategies revisited: 10-year systematic review. true true /api/journal/10038876 REVIEWED true false 10038876 false 10038876 true 2215-0366 2215-0374 Journal FOREIGN 3 7 646 659 646 14 2016 BACKGROUND: Many countries are developing suicide prevention strategies for which up-to-date, high-quality evidence is required. We present updated evidence for the effectiveness of suicide prevention interventions since 2005. METHODS: We searched PubMed and the Cochrane Library using multiple terms related to suicide prevention for studies published between Jan 1, 2005, and Dec 31, 2014. We assessed seven interventions: public and physician education, media strategies, screening, restricting access to suicide means, treatments, and internet or hotline support. Data were extracted on primary outcomes of interest, namely suicidal behaviour (suicide, attempt, or ideation), and intermediate or secondary outcomes (treatment-seeking, identification of at-risk individuals, antidepressant prescription or use rates, or referrals). 18 suicide prevention experts from 13 European countries reviewed all articles and rated the strength of evidence using the Oxford criteria. Because the heterogeneity of populations and methodology did not permit formal meta-analysis, we present a narrative analysis. FINDINGS: We identified 1797 studies, including 23 systematic reviews, 12 meta-analyses, 40 randomised controlled trials (RCTs), 67 cohort trials, and 22 ecological or population-based investigations. Evidence for restricting access to lethal means in prevention of suicide has strengthened since 2005, especially with regard to control of analgesics (overall decrease of 43% since 2005) and hot-spots for suicide by jumping (reduction of 86% since 2005, 79% to 91%). School-based awareness programmes have been shown to reduce suicide attempts (odds ratio [OR] 0.45, 95% CI 0.24-0.85; p=0.014) and suicidal ideation (0.5, 0.27-0.92; p=0.025). The anti-suicidal effects of clozapine and lithium have been substantiated, but might be less specific than previously thought. Effective pharmacological and psychological treatments of depression are important in prevention. Insufficient evidence exists to assess the possible benefits for suicide prevention of screening in primary care, in general public education and media guidelines. Other approaches that need further investigation include gatekeeper training, education of physicians, and internet and helpline support. The paucity of RCTs is a major limitation in the evaluation of preventive interventions. INTERPRETATION: In the quest for effective suicide prevention initiatives, no single strategy clearly stands above the others. Combinations of evidence-based strategies at the individual level and the population level should be assessed with robust research designs. FUNDING: The Expert Platform on Mental Health, Focus on Depression, and the European College of Neuropsychopharmacology. true true 2016 796696 true true true false true false PAY 2026-05-17 false 1431 7 1431 1359 11 1409 1375 1269 1331 1422 1422 1350 1350 1359 72 0 1431 1359 1431 1359 0 8 8 Folyóiratcikk Journal Article 24 1365 Könyvrészlet Chapter in Book 25 51 Könyv Book 23 14 Egyéb konferenciaközlemény Conference paper 31 1 Egyéb konferenciakötet Conference proceedings 32 0 Oltalmi formák Protection forms 26 0 Disszertáció Thesis 28 0 Egyéb Miscellaneous 29 0 Alkotás Achievement 22 0 Kutatási adat Research data 33 0 Folyóiratcikk Journal Article 24 0 0 0 Könyvrészlet Chapter in Book 25 0 0 0 Könyv Book 23 0 0 0 Egyéb konferenciaközlemény Conference paper 31 0 0 0 Egyéb konferenciakötet Conference proceedings 32 0 0 0 Oltalmi formák Protection forms 26 0 0 0 Disszertáció Thesis 28 0 0 0 Egyéb Miscellaneous 29 0 0 0 Alkotás Achievement 22 0 0 0 Kutatási adat Research data 33 0 0 0 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/api/authorship/8103072 9 0.055555556 false false Barzilay R true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491637 true PersonAuthorship 8103073 /api/authorship/8103073 10 0.055555556 false false Author 10011527 /api/author/10011527 Balázs Judit true 10011527 true Balazs J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491636 true PersonAuthorship 8103074 /api/authorship/8103074 11 0.055555556 false false Author 10023077 /api/author/10023077 Purebl György true 10023077 true Purebl G true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491635 true PersonAuthorship 8103075 /api/authorship/8103075 12 0.055555556 false false Kahn JP true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491634 true PersonAuthorship 8103076 /api/authorship/8103076 13 0.055555556 false false Saiz PA true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491633 true PersonAuthorship 8103077 /api/authorship/8103077 14 0.055555556 false false Lipsicas CB true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491632 true PersonAuthorship 8103078 /api/authorship/8103078 15 0.055555556 false false Bobes J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491631 true PersonAuthorship 8103079 /api/authorship/8103079 16 0.055555556 false false Cozman D true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491630 true PersonAuthorship 8103080 /api/authorship/8103080 17 0.055555556 false false Hegerl U true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491629 true PersonAuthorship 8103081 /api/authorship/8103081 18 0.055555556 false true Zohar J true false false AuthorshipType 1 /api/authorshiptype/1 0 true 0 true false 24491628 true PublicationIdentifier 1113036 /api/publicationidentifier/1113036 PlainSource 6 /api/publicationsource/6 PublicationSourceType 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title="Idézőközlemény" style="float: left" src="/frontend/resources/grid/publication-citation-icon.png"> <div class="autype autype0"> <span class="author-name" >Zalsman G ✉ </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hawton K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Wasserman D </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >van Heeringen K </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Arensman E </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Sarchiapone M </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Carli V </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hoschl C </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Barzilay R </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" mtid="10011527"><a href="/gui2/?type=authors&mode=browse&sel=10011527" target="_blank">Balazs J (<span class="authorship-author-name">Balázs Judit</span> <span class="authorAux-mtmt"> Gyermekpszichiátria</span>) </a> </span> <span 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class="author-name" >Cozman D </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Hegerl U </span> ;&nbsp;&nbsp;&nbsp; <span class="author-name" >Zohar J </span> </div> </div> <div class="title"><a href="/gui2/?mode=browse&params=publication;3091887" target="_blank">Suicide prevention strategies revisited: 10-year systematic review.</a></div> <div> <span class="journal-title">LANCET PSYCHIATRY</span> <span class="journal-issn">(<a target="_blank" href="https://portal.issn.org/resource/ISSN/2215-0366">2215-0366</a> <a target="_blank" href="https://portal.issn.org/resource/ISSN/2215-0374">2215-0374</a>)</span>: <span class="journal-volume">3</span> <span class="journal-issue">7</span> <span class="page"> pp 646-659 </span> <span class="year">(2016)</span> </div> <div class="pub-footer"> <span class="language" xmlns="http://www.w3.org/1999/html">Nyelv: Angol | </span> <span class="identifiers"> <span class="id identifier oa_PAY" title=" Fizetős "> <a style="color:blue" 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</span> | <span class="pub-category">Tudományos</span> | <span class="publication-sourceOfData">MEDLINE</span> </div> <div class="lastModified">Utolsó módosítás: 2019.11.12. 12:16 Molnár-Taga Márta (SE 4-es admin) </div> <pre class="comment" style="margin-top: 0; margin-bottom: 0;"><u>Megjegyzés</u>: Geha Mental Health Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel Division of Molecular Imaging and Neuropathology, Department of Psychiatry, Columbia University, New York, NY, United States Centre for Suicide Research, University of Oxford, Oxford, United Kingdom National Centre for Suicide Re...</pre> </div></div>