Endoscopic versus microscopic stapes surgery outcomes : A meta-analysis and systematic review

Koukkoullis, Alexandros ✉ [Koukkoullis, Alexandros (Fül-orr-gégészet), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Tóth, István* [Tóth, István (Fül-orr-gégegyógy...), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Gede, Noémi [Gede, Noémi (Egészségtudomány), author] Szentágothai Research Centre (UP); Institute for Translational Medicine (UP / UPMS); Szakács, Zsolt [Szakács, Zsolt (Transzlációs Medi...), author] Institute for Translational Medicine (UP / UPMS); Translational Medicine Research Group (UP / SZRC); Hegyi, Péter [Hegyi, Péter (Gasztroenterológia), author] 1st Department of Internal Medicine (UP / UPMS); First Department of Internal Medicine (SZTE / ASZMS / DIMedicine); MTA-SZTE Momentum Translational Gastroenterolog... (SZTE / ASZMS / DIMedicine...; Institute for Translational Medicine (UP / UPMS); Translational Medicine Research Group (UP / SZRC); Varga, Gábor [Varga, Gábor (Élettan, orálbiol...), author] Department of Oral Biology (SU / FD); Pap, István [Pap, István (Fül-orr-gégegyógy...), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Harmat, Kinga [Harmat, Kinga (Fül-orr-gégészet), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Németh, Adrienn [Németh, Adrienn (Fül-orr-gégészet), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Szanyi, István [Szanyi, István (Fül-orr-gégegyógy...), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Lujber, László [Lujber, László (Fül-orr-gége és f...), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Gerlinger, Imre [Gerlinger, Imre (Fül-orr-gégészet), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS); Révész, Péter [Révész, Péter (PhD Orvostudomány), author] ENT Department (Department of Oto-rhino-laryngo... (UP / UPMS)

English Article (Journal Article) Scientific
Published: LARYNGOSCOPE 0023-852X 1531-4995 130 (8) pp. 2019-2027 2020
  • SJR Scopus - Otorhinolaryngology: D1
Identifiers
Fundings:
  • (3.6.2-16-2017-00002) Funder: EFOP
  • (2.3.2-15-2016-00048) Funder: GINOP
  • EFOP(EFOP-3.6.2-16-2017-00006) Funder: EFOP
Subjects:
  • Meta-analysis
  • Microsurgery
Compare intraoperative and postoperative outcomes of endoscopic and microscopic stapes surgery to provide objective evidence on whether the former is a better alternative than the latter.We performed a systematic review and meta-analysis for studies that compared endoscopic stapes surgery with microscopic stapes surgery. Only studies that met predetermined criteria were selected and assessed for bias and quality. Primary outcomes were postoperative air-bone gap (ABG) and chorda tympani nerve injury. Secondary outcomes were average operating time, tympanic membrane (TM) perforation, and postoperative taste disturbance, pain, and dizziness. We calculated pooled odds ratios (ORs) with 95% confidence intervals (CIs) for dichotomous outcomes and weighted mean difference (WMD) with 95% CI for continuous outcomes. A confidence interval starting above 1.0 was considered as statistically significant. I2 and χ2 tests were used to quantify statistical heterogeneity. We used funnel plots to look for publication bias and performed a sensitivity analysis.Six nonrandomized cohort studies were eligible. The primary outcomes were ABG < 10 dB: OR = 1.80 (95% CI: 0.96 to 3.38), ABG = 11 dB to 20 dB: OR = 1.49 (95% CI: 0.76 to 2.93), ABG > 20 dB: OR = 2.51 (95% CI: 0.77 to 8.22), and chorda tympani injury: OR = 3.51 (95% CI: 1.55 to 7.93). Secondary outcomes were taste: OR = 2.36 (95% CI: 1.01 to 5.51), average operation time: WMD = 0.14 (95% CI: -11.69 to 11.98), TM perforation: OR = 1.70 (95% CI: 0.44 to 6.58); pain: OR = 0.84 (95% CI: 0.36 to 1.96), and dizziness: OR = 2.15 (95% CI: 0.94 to 4.89).Endoscopic stapes surgery is a valid alternative to the microscope.2a Laryngoscope, 2019.
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2025-04-14 06:46