Selective deposition of peptides from liquid solutions to n- and p-doped silicon has
been demonstrated. The selectivity is governed by peptide/silicon adhesion differences.
A non-invasive, fast characterization of the obtained peptide layers is required to
promote their application for interfacing silicon-based devices with biological material.
In this study we show that spectroscopic ellipsometry - a method increasingly used
for the investigation of bio-interfaces - can provide essential information about
the amount of adsorbed peptide material and the degree of coverage on silicon surfaces.
We observed the formation of peptide multilayers for a strongly binding adhesion peptide
on p-doped silicon. Application of the patterned layer ellipsometric evaluation method
combined with Sellmeier-dispersion led to physically consistent results, which describe
well the optical properties of peptide layers in the visible spectral range. This
evaluation allowed the estimation of surface coverage, which is an important indicator
of adsorption quality. The ellipsometric findings were well supported by atomic force